P00531
Gene name |
V-MIL (V-MHT) |
Protein name |
Serine/threonine-protein kinase-transforming protein mil |
Names |
|
Species |
Avian retrovirus MH2 |
KEGG Pathway |
|
EC number |
2.7.11.1: Protein-serine/threonine kinases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
0 structures for P00531
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|
No variants for P00531
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P00531 | |||||
No associated diseases with P00531
4 regional properties for P00531
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Protein kinase domain | 82 - 341 | IPR000719 |
| domain | Serine-threonine/tyrosine-protein kinase, catalytic domain | 84 - 338 | IPR001245 |
| active_site | Serine/threonine-protein kinase, active site | 197 - 209 | IPR008271 |
| binding_site | Protein kinase, ATP binding site | 88 - 108 | IPR017441 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.7.11.1 | Protein-serine/threonine kinases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| protein serine kinase activity | Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate. |
| protein serine/threonine kinase activity | Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| protein phosphorylation | The process of introducing a phosphate group on to a protein. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| PTMPVDSRII | EDAIRNHSES | ASPSASSGSP | NNMSPTGWSQ | PKTPVPAQRE | RAPGTNTQEK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| NKIRPRGQRD | SSYYWEIEAS | EVLLSTRIGS | GSFGTVYKGK | WHGDVAVKIL | KVVDPTPEQF |
| 130 | 140 | 150 | 160 | 170 | 180 |
| QAFRNEVAVL | RKTRHVNILL | FMGYMTKDNL | AIVTQWCEGS | SLYKHLHVQE | TKFQMFQLID |
| 190 | 200 | 210 | 220 | 230 | 240 |
| IARQTAQGMD | YLHAKNIIHR | DMKSNNIFLH | GGLTVKIGDF | GLATVKSRWS | GSQQVEQPTG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SILWMAPEVI | RMQDSNPFSF | QSDVYSYGIV | LYELMTGELP | YSHINNRDQI | IFMVGRGYAS |
| 310 | 320 | 330 | 340 | 350 | 360 |
| PDLSKLYKNC | PKAMKRLVAD | CLKKVREERP | LFPQILSSIA | LLQHSLPKIN | RSASEPSLHR |
| 370 | |||||
| ASHTEDINSC | TLTSTRLPVF |