P00489

PR
Gene name
PYGM
Protein name
Glycogen phosphorylase, muscle form
Names
Myophosphorylase
Species
Oryctolagus cuniculus (Rabbit)
KEGG Pathway
ocu:100008972
EC number
2.4.1.1: Hexosyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-50 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

226 structures for P00489

Entry ID Method Resolution Chain Position Source
1A8I X-ray 178 A A 2-843 PDB
1ABB X-ray 280 A A/B/C/D 11-838 PDB
1AXR X-ray 230 A A 2-843 PDB
1B4D X-ray 200 A A 2-843 PDB
1BX3 X-ray 230 A A 2-843 PDB
1C50 X-ray 230 A A 14-843 PDB
1C8K X-ray 176 A A 2-843 PDB
1C8L X-ray 230 A A 2-843 PDB
1E1Y X-ray 223 A A 2-843 PDB
1FS4 X-ray 238 A A 2-843 PDB
1FTQ X-ray 235 A A 2-843 PDB
1FTW X-ray 236 A A 2-843 PDB
1FTY X-ray 238 A A 2-843 PDB
1FU4 X-ray 236 A A 2-843 PDB
1FU7 X-ray 236 A A 2-843 PDB
1FU8 X-ray 235 A A 2-843 PDB
1GFZ X-ray 230 A A 2-843 PDB
1GG8 X-ray 231 A A 2-843 PDB
1GGN X-ray 236 A A 2-843 PDB
1GPA X-ray 290 A A/B/C/D 2-843 PDB
1GPB X-ray 190 A A 2-843 PDB
1GPY X-ray 240 A A 2-843 PDB
1H5U X-ray 176 A A 2-843 PDB
1HLF X-ray 226 A A 2-843 PDB
1K06 X-ray 180 A A 2-843 PDB
1K08 X-ray 226 A A 2-843 PDB
1KTI X-ray 197 A A 2-843 PDB
1LWN X-ray 200 A A 2-843 PDB
1LWO X-ray 200 A A 2-843 PDB
1NOI X-ray 250 A A/B/C/D 2-843 PDB
1NOJ X-ray 240 A A 2-843 PDB
1NOK X-ray 240 A A 2-843 PDB
1P29 X-ray 220 A A 2-843 PDB
1P2B X-ray 220 A A 2-843 PDB
1P2D X-ray 194 A A 2-843 PDB
1P2G X-ray 230 A A 2-843 PDB
1P4G X-ray 210 A A 2-843 PDB
1P4H X-ray 206 A A 2-843 PDB
1P4J X-ray 200 A A 2-843 PDB
1PYG X-ray 287 A A/B/C/D 2-843 PDB
1UZU X-ray 230 A A 2-843 PDB
1WUT X-ray 226 A A 2-843 PDB
1WUY X-ray 226 A A 2-843 PDB
1WV0 X-ray 226 A A 2-843 PDB
1WV1 X-ray 226 A A 2-843 PDB
1WW2 X-ray 190 A A 2-843 PDB
1WW3 X-ray 180 A A 2-843 PDB
1XC7 X-ray 183 A A 2-843 PDB
1XKX X-ray 193 A A 2-843 PDB
1XL0 X-ray 192 A A 2-843 PDB
1XL1 X-ray 210 A A 2-843 PDB
1Z62 X-ray 190 A A 2-843 PDB
1Z6P X-ray 240 A A 2-843 PDB
1Z6Q X-ray 203 A A 2-843 PDB
2AMV X-ray 230 A A 2-843 PDB
2F3P X-ray 194 A A 2-843 PDB
2F3Q X-ray 196 A A 2-843 PDB
2F3S X-ray 196 A A 2-843 PDB
2F3U X-ray 193 A A 2-843 PDB
2FET X-ray 203 A A 2-843 PDB
2FF5 X-ray 203 A A 2-843 PDB
2FFR X-ray 203 A A 13-837 PDB
2G9Q X-ray 250 A A 2-843 PDB
2G9R X-ray 207 A A 2-843 PDB
2G9U X-ray 215 A A 2-843 PDB
2G9V X-ray 215 A A 2-843 PDB
2GJ4 X-ray 160 A A 13-836 PDB
2GM9 X-ray 230 A A 13-837 PDB
2GPA X-ray 200 A A 2-843 PDB
2GPB X-ray 230 A A 2-843 PDB
2GPN X-ray 199 A A 2-843 PDB
2IEG X-ray 190 A A/B 2-843 PDB
2IEI X-ray 191 A A/B 2-843 PDB
2OFF X-ray 220 A A 2-843 PDB
2PRI X-ray 230 A A 2-843 PDB
2PRJ X-ray 230 A A 2-843 PDB
2PYD X-ray 193 A A 1-843 PDB
2PYI X-ray 188 A A 1-843 PDB
2QLM X-ray 210 A A 2-843 PDB
2QLN X-ray 215 A A 2-843 PDB
2QN1 X-ray 240 A A 2-843 PDB
2QN2 X-ray 270 A A 2-843 PDB
2QN3 X-ray 196 A A 2-843 PDB
2QN7 X-ray 183 A A 2-843 PDB
2QN8 X-ray 190 A A 2-843 PDB
2QN9 X-ray 200 A A 2-843 PDB
2QNB X-ray 180 A A 2-843 PDB
2QRG X-ray 185 A A 2-843 PDB
2QRH X-ray 183 A A 2-843 PDB
2QRM X-ray 190 A A 2-843 PDB
2QRP X-ray 186 A A 2-843 PDB
2QRQ X-ray 180 A A 2-843 PDB
2SKC X-ray 240 A A 2-843 PDB
2SKD X-ray 240 A A 2-843 PDB
2SKE X-ray 246 A A 2-843 PDB
3AMV X-ray 210 A A 2-843 PDB
3BCR X-ray 214 A A 2-843 PDB
3BCS X-ray 200 A A 2-843 PDB
3BCU X-ray 203 A A 2-843 PDB
3BD6 X-ray 200 A A 2-843 PDB
3BD7 X-ray 190 A A 2-843 PDB
3BD8 X-ray 210 A A 2-843 PDB
3BDA X-ray 200 A A 2-843 PDB
3CUT X-ray 230 A A 2-843 PDB
3CUU X-ray 230 A A 2-843 PDB
3CUV X-ray 193 A A 2-843 PDB
3CUW X-ray 200 A A 2-843 PDB
3E3L X-ray 259 A A/B/C/D 2-843 PDB
3E3N X-ray 270 A A/B/C/D/E/F/G/H 2-843 PDB
3E3O X-ray 260 A A/B/C/D 2-843 PDB
3EBO X-ray 190 A A 2-843 PDB
3EBP X-ray 200 A A 2-843 PDB
3G2H X-ray 203 A A 2-843 PDB
3G2I X-ray 200 A A 2-843 PDB
3G2J X-ray 214 A A 2-843 PDB
3G2K X-ray 200 A A 2-843 PDB
3G2L X-ray 230 A A 2-843 PDB
3G2N X-ray 210 A A 2-843 PDB
3GPB X-ray 230 A A 2-843 PDB
3L79 X-ray 186 A A 1-843 PDB
3L7A X-ray 190 A A 1-843 PDB
3L7B X-ray 200 A A 1-843 PDB
3L7C X-ray 193 A A 1-843 PDB
3L7D X-ray 200 A A 1-843 PDB
3MQF X-ray 195 A A 2-843 PDB
3MRT X-ray 198 A A 2-843 PDB
3MRV X-ray 194 A A 2-843 PDB
3MRX X-ray 195 A A 2-843 PDB
3MS2 X-ray 210 A A 2-843 PDB
3MS4 X-ray 207 A A 2-843 PDB
3MS7 X-ray 195 A A 2-843 PDB
3MSC X-ray 195 A A 2-843 PDB
3MT7 X-ray 200 A A 2-843 PDB
3MT8 X-ray 200 A A 2-843 PDB
3MT9 X-ray 205 A A 2-843 PDB
3MTA X-ray 223 A A 2-843 PDB
3MTB X-ray 195 A A 2-843 PDB
3MTD X-ray 210 A A 2-843 PDB
3NC4 X-ray 207 A A 3-843 PDB
3NP7 X-ray 205 A A 2-843 PDB
3NP9 X-ray 200 A A 2-843 PDB
3NPA X-ray 197 A A 2-843 PDB
3S0J X-ray 200 A A 2-843 PDB
3SYM X-ray 240 A A 2-843 PDB
3SYR X-ray 240 A A 2-843 PDB
3T3D X-ray 250 A A 2-843 PDB
3T3E X-ray 215 A A 2-843 PDB
3T3G X-ray 240 A A 2-843 PDB
3T3H X-ray 260 A A 2-843 PDB
3T3I X-ray 265 A A 2-843 PDB
3ZCP X-ray 183 A A 1-843 PDB
3ZCQ X-ray 215 A A 1-843 PDB
3ZCR X-ray 207 A A 1-843 PDB
3ZCS X-ray 203 A A 1-843 PDB
3ZCT X-ray 200 A A 1-843 PDB
3ZCU X-ray 205 A A 1-843 PDB
3ZCV X-ray 183 A A 1-843 PDB
4CTM X-ray 195 A A 1-843 PDB
4CTN X-ray 210 A A 1-843 PDB
4CTO X-ray 190 A A 1-843 PDB
4EJ2 X-ray 265 A A 13-837 PDB
4EKE X-ray 260 A A 13-837 PDB
4EKY X-ray 245 A A 13-837 PDB
4EL0 X-ray 240 A A 13-837 PDB
4EL5 X-ray 200 A A 13-837 PDB
4GPB X-ray 230 A A 2-843 PDB
4MHO X-ray 200 A A 13-837 PDB
4MHS X-ray 200 A A 13-837 PDB
4MI3 X-ray 215 A A 13-837 PDB
4MI6 X-ray 190 A A 13-837 PDB
4MI9 X-ray 185 A A 13-837 PDB
4MIC X-ray 245 A A 13-837 PDB
4MRA X-ray 234 A A 13-837 PDB
4YI3 X-ray 180 A A 1-843 PDB
4YI5 X-ray 180 A A 1-843 PDB
4YUA X-ray 200 A A 13-837 PDB
4Z5X X-ray 210 A A 1-843 PDB
5GPB X-ray 230 A A 2-843 PDB
5JTT X-ray 185 A A 1-843 PDB
5JTU X-ray 185 A A 1-843 PDB
5LRC X-ray 200 A A 2-843 PDB
5LRD X-ray 180 A A 1-843 PDB
5LRE X-ray 180 A A 2-843 PDB
5LRF X-ray 175 A A 2-843 PDB
5MCB X-ray 195 A A 13-837 PDB
5MEM X-ray 178 A A 1-843 PDB
5O50 X-ray 190 A A 2-843 PDB
5O52 X-ray 190 A A 1-843 PDB
5O54 X-ray 245 A A 1-843 PDB
5O56 X-ray 245 A A 1-843 PDB
5OWY X-ray 190 A A 1-843 PDB
5OWZ X-ray 185 A A 1-843 PDB
5OX0 X-ray 190 A A 1-843 PDB
5OX1 X-ray 185 A A 1-843 PDB
5OX3 X-ray 190 A A 1-843 PDB
5OX4 X-ray 180 A A 1-843 PDB
6F3J X-ray 220 A A 1-843 PDB
6F3L X-ray 190 A A 1-843 PDB
6F3R X-ray 190 A A 1-843 PDB
6F3S X-ray 190 A A 1-843 PDB
6F3U X-ray 220 A A 1-843 PDB
6GPB X-ray 286 A A 2-843 PDB
6QA6 X-ray 240 A A 1-843 PDB
6QA7 X-ray 236 A A 1-843 PDB
6QA8 X-ray 235 A A 1-843 PDB
6R0H X-ray 250 A A 1-843 PDB
6R0I X-ray 240 A A 1-843 PDB
6S4H X-ray 245 A A 1-843 PDB
6S4K X-ray 243 A A 1-843 PDB
6S4O X-ray 235 A A 1-843 PDB
6S4P X-ray 237 A A 1-843 PDB
6S4R X-ray 230 A A 1-843 PDB
6S51 X-ray 237 A A 1-843 PDB
6S52 X-ray 237 A A 1-843 PDB
6Y55 X-ray 238 A A 1-843 PDB
6Y5C X-ray 240 A A 2-843 PDB
6Y5O X-ray 233 A A 2-843 PDB
6YVE X-ray 210 A AAA 1-843 PDB
7GPB X-ray 290 A A/B/C/D 2-843 PDB
7ONF X-ray 160 A A 13-837 PDB
7P7D X-ray 145 A A 8-837 PDB
7Q5I X-ray 180 A AAA 1-843 PDB
8BZS X-ray 225 A A 1-843 PDB
8GPB X-ray 220 A A 2-843 PDB
9GPB X-ray 290 A A/B/C/D 2-843 PDB
AF-P00489-F1 Predicted AlphaFoldDB

No variants for P00489

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P00489

No associated diseases with P00489

1 regional properties for P00489

Type Name Position InterPro Accession
conserved_site Phosphorylase pyridoxal-phosphate attachment site 673 - 685 IPR035090

Functions

Description
EC Number 2.4.1.1 Hexosyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
skeletal muscle myofibril A myofibril of a skeletal muscle fiber.

5 GO annotations of molecular function

Name Definition
glycogen phosphorylase activity Catalysis of the reaction: glycogen + phosphate = maltodextrin + alpha-D-glucose 1-phosphate.
linear malto-oligosaccharide phosphorylase activity Catalysis of the reaction: hydrogenphosphate + a linear malto-oligosaccharide = alpha-D-glucose 1-phosphate + a linear malto-oligosaccharide.
nucleotide binding Binding to a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose.
pyridoxal phosphate binding Binding to pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.
SHG alpha-glucan phosphorylase activity Catalysis of the reaction: hydrogenphosphate + a plant soluble heteroglycan = alpha-D-glucose 1-phosphate + a plant soluble heteroglycan.

1 GO annotations of biological process

Name Definition
glycogen catabolic process The chemical reactions and pathways resulting in the breakdown of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSRPLSDQEK RKQISVRGLA GVENVTELKK NFNRHLHFTL VKDRNVATPR DYYFALAHTV
70 80 90 100 110 120
RDHLVGRWIR TQQHYYEKDP KRIYYLSLEF YMGRTLQNTM VNLALENACD EATYQLGLDM
130 140 150 160 170 180
EELEEIEEDA GLGNGGLGRL AACFLDSMAT LGLAAYGYGI RYEFGIFNQK ICGGWQMEEA
190 200 210 220 230 240
DDWLRYGNPW EKARPEFTLP VHFYGRVEHT SQGAKWVDTQ VVLAMPYDTP VPGYRNNVVN
250 260 270 280 290 300
TMRLWSAKAP NDFNLKDFNV GGYIQAVLDR NLAENISRVL YPNDNFFEGK ELRLKQEYFV
310 320 330 340 350 360
VAATLQDIIR RFKSSKFGCR DPVRTNFDAF PDKVAIQLND THPSLAIPEL MRVLVDLERL
370 380 390 400 410 420
DWDKAWEVTV KTCAYTNHTV LPEALERWPV HLLETLLPRH LQIIYEINQR FLNRVAAAFP
430 440 450 460 470 480
GDVDRLRRMS LVEEGAVKRI NMAHLCIAGS HAVNGVARIH SEILKKTIFK DFYELEPHKF
490 500 510 520 530 540
QNKTNGITPR RWLVLCNPGL AEIIAERIGE EYISDLDQLR KLLSYVDDEA FIRDVAKVKQ
550 560 570 580 590 600
ENKLKFAAYL EREYKVHINP NSLFDVQVKR IHEYKRQLLN CLHVITLYNR IKKEPNKFVV
610 620 630 640 650 660
PRTVMIGGKA APGYHMAKMI IKLITAIGDV VNHDPVVGDR LRVIFLENYR VSLAEKVIPA
670 680 690 700 710 720
ADLSEQISTA GTEASGTGNM KFMLNGALTI GTMDGANVEM AEEAGEENFF IFGMRVEDVD
730 740 750 760 770 780
RLDQRGYNAQ EYYDRIPELR QIIEQLSSGF FSPKQPDLFK DIVNMLMHHD RFKVFADYEE
790 800 810 820 830 840
YVKCQERVSA LYKNPREWTR MVIRNIATSG KFSSDRTIAQ YAREIWGVEP SRQRLPAPDE
KIP