P00468

PR
Gene name
nifK (all1440)
Protein name
Nitrogenase molybdenum-iron protein beta chain
Names
Dinitrogenase, Nitrogenase component I
Species
Nostoc sp (strain PCC 7120 / SAG 2582 / UTEX 2576)
KEGG Pathway
ana:all1440
EC number
1.18.6.1: With dinitrogen as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-73 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P00468

Entry ID Method Resolution Chain Position Source
AF-P00468-F1 Predicted AlphaFoldDB

No variants for P00468

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P00468

No associated diseases with P00468

3 regional properties for P00468

Type Name Position InterPro Accession
conserved_site Nitrogenase component 1, conserved site 151 - 165 IPR000318
domain Nitrogenase/oxidoreductase, component 1 70 - 490 IPR000510
domain Nitrogenase molybdenum-iron protein beta chain, N-terminal 1 - 56 IPR024564

Functions

Description
EC Number 1.18.6.1 With dinitrogen as acceptor
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
molybdenum-iron nitrogenase complex An enzyme complex containing a molybdenum-iron cluster found in many species. It is composed of two proteins, dinitrogenase and nitrogenase reductase; dinitrogenase, the molybdenum-iron protein, is tetrameric with an alpha2-beta2 structure, and nitrogenase reductase is a homodimer.

5 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
carbonyl sulfide nitrogenase activity Catalysis of the reaction: carbonyl sulfide + 2 H+ + 2 e- = hydrogen sulfide + carbon monoxide.
iron-sulfur cluster binding Binding to an iron-sulfur cluster, a combination of iron and sulfur atoms.
metal ion binding Binding to a metal ion.
nitrogenase activity Catalysis of the reaction: 8 reduced ferredoxin + 8 H+ + N2 + 16 ATP + 16 H2O = 8 oxidized ferredoxin + 2 NH3 + 16 ADP + 16 phosphate.

1 GO annotations of biological process

Name Definition
nitrogen fixation The process in which nitrogen is taken from its relatively inert molecular form (N2) in the atmosphere and converted into nitrogen compounds useful for other chemical processes, such as ammonia, nitrate and nitrogen dioxide.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPQNPERTVD HVDLFKQPEY TELFENKRKN FEGAHPPEEV ERVSEWTKSW DYREKNFARE
70 80 90 100 110 120
ALTVNPAKGC QPVGAMFAAL GFEGTLPFVQ GSQGCVAYFR THLSRHYKEP CSAVSSSMTE
130 140 150 160 170 180
DAAVFGGLNN MIEGMQVSYQ LYKPKMIAVC TTCMAEVIGD DLGAFITNSK NAGSIPQDFP
190 200 210 220 230 240
VPFAHTPSFV GSHITGYDNM MKGILSNLTE GKKKATSNGK INFIPGFDTY VGNNRELKRM
250 260 270 280 290 300
MGVMGVDYTI LSDSSDYFDS PNMGEYEMYP GGTKLEDAAD SINAKATVAL QAYTTPKTRE
310 320 330 340 350 360
YIKTQWKQET QVLRPFGVKG TDEFLTAVSE LTGKAIPEEL EIERGRLVDA ITDSYAWIHG
370 380 390 400 410 420
KKFAIYGDPD LIISITSFLL EMGAEPVHIL CNNGDDTFKK EMEAILAASP FGKEAKVWIQ
430 440 450 460 470 480
KDLWHFRSLL FTEPVDFFIG NSYGKYLWRD TSIPMVRIGY PLFDRHHLHR YSTLGYQGGL
490 500 510
NILNWVVNTL LDEMDRSTNI TGKTDISFDL IR