O97157

PR
Gene name
Protein name
Alkyldihydroxyacetonephosphate synthase
Names
Alkyl-DHAP synthase, Alkylglycerone-phosphate synthase
Species
Trypanosoma brucei brucei
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

36-107 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O97157

Entry ID Method Resolution Chain Position Source
AF-O97157-F1 Predicted AlphaFoldDB

No variants for O97157

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O97157

No associated diseases with O97157

3 regional properties for O97157

Type Name Position InterPro Accession
domain FAD-binding oxidoreductase/transferase, type 4, C-terminal 307 - 576 IPR004113
domain FAD linked oxidase, N-terminal 130 - 270 IPR006094
domain FAD-binding domain, PCMH-type 126 - 307 IPR016166

Functions

Description
EC Number
Subcellular Localization
  • Peroxisome
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
peroxisome A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.

2 GO annotations of molecular function

Name Definition
alkylglycerone-phosphate synthase activity Catalysis of the reaction: 1-acyl-glycerone 3-phosphate + a long-chain alcohol = 1-alkyl-glycerone 3-phosphate + a long-chain acid anion.
FAD binding Binding to the oxidized form, FAD, of flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.

1 GO annotations of biological process

Name Definition
ether lipid biosynthetic process The chemical reactions and pathways resulting in the formation of ether lipids, lipids that contain (normally) one lipid alcohol in ether linkage to one of the carbon atoms (normally C-1) of glycerol.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDKRMITDAF EEIKWNGWGD TGVCIKYDEA RQLPIHTNGK PMKHLLKFMK DDVLKVKGEF
70 80 90 100 110 120
KIKPTPGLTK EEAIKRLPPP VVKQPFVDEL RQVLSKDQIR LDAYARLTHI FGKNYRDLWR
130 140 150 160 170 180
VRRGMIDRPP DAVILPNNHD DCVKIMELAQ KHNVVVVPFG GGTNVTGGVE PNPFETRRMV
190 200 210 220 230 240
ISIDMRRMGR MLHIDTESGT AVFEVGVLGP DIDEQLSRYG FMMGHDPDSY AYSTLGGWIA
250 260 270 280 290 300
ARGSGAMSNK YGDIENMILA MRVVTPVGVV ETPLTSRPCG VDLNAMFVGS EGAFGLVTEA
310 320 330 340 350 360
VVKIERLPEV KRYEGWLFPS FEVAFTAFHT CTRKGIHPCT MRLYDEDDTR LSFAASTDSG
370 380 390 400 410 420
LVSTFFSKCF KKYIATVKGW NLSKISLVVV GFEGTKAQTN CQRSELVGVF QAFGATCLGT
430 440 450 460 470 480
KPGNTWQEKK YDLPYLRDFA LAHNFWADVF ETSVLYTDAI HCWRAVKKSF AEVMAENGKN
490 500 510 520 530 540
AWIGCHTAHQ YRFGCCLYFT FIGGQADEND LKIFLQVKKR AMEVMLQHRG NLTHHHGIGY
550 560 570 580 590 600
EHVPWMKRYN GEGGLDAIMK FKKALDPKNI CNPGKLLPSP PSEKETPKAT QARQNREMMF
610
DKMGIPGALQ AHL