O96759

PR
Gene name
eapA (DDB_G0286183)
Protein name
Alkyldihydroxyacetonephosphate synthase
Names
Alkyl-DHAP synthase, Alkylglycerone-phosphate synthase
Species
Dictyostelium discoideum (Slime mold)
KEGG Pathway
ddi:DDB_G0286183
EC number
2.5.1.26: Transferring alkyl or aryl groups, other than methyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

19-114 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

3 structures for O96759

Entry ID Method Resolution Chain Position Source
2UUU X-ray 195 A A/B/C/D 9-587 PDB
2UUV X-ray 199 A A/B/C/D 9-587 PDB
AF-O96759-F1 Predicted AlphaFoldDB

No variants for O96759

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O96759

No associated diseases with O96759

3 regional properties for O96759

Type Name Position InterPro Accession
domain FAD-binding oxidoreductase/transferase, type 4, C-terminal 318 - 586 IPR004113
domain FAD linked oxidase, N-terminal 141 - 279 IPR006094
domain FAD-binding domain, PCMH-type 137 - 317 IPR016166

Functions

Description
EC Number 2.5.1.26 Transferring alkyl or aryl groups, other than methyl groups
Subcellular Localization
  • Peroxisome
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
peroxisome A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.

5 GO annotations of molecular function

Name Definition
alcohol binding Binding to an alcohol, any of a class of alkyl compounds containing a hydroxyl group.
alkylglycerone-phosphate synthase activity Catalysis of the reaction: 1-acyl-glycerone 3-phosphate + a long-chain alcohol = 1-alkyl-glycerone 3-phosphate + a long-chain acid anion.
FAD binding Binding to the oxidized form, FAD, of flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.
flavin adenine dinucleotide binding Binding to FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2.
identical protein binding Binding to an identical protein or proteins.

1 GO annotations of biological process

Name Definition
ether lipid biosynthetic process The chemical reactions and pathways resulting in the formation of ether lipids, lipids that contain (normally) one lipid alcohol in ether linkage to one of the carbon atoms (normally C-1) of glycerol.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSGEKKEYPK EHIDLYQQIK WNGWGDTRKF LHQLKPSGTI AMTTPEVSSV PLPSLRGFIK
70 80 90 100 110 120
KELTLPGEED KPFVLDETPA LQIENIHVDP PKQYPEFVRE LKAFFLPDQL KDDKLARITH
130 140 150 160 170 180
TFGKSLRDLI RVRIGQVKNA PDLIVLPHSH EEVERLVQLA HKYNVVIIPM GGGSNIVGAI
190 200 210 220 230 240
EPVSNERFTV SIDMRRMNKV LWVDRREMTA CIQVGIMGPE LEKQLHKQGV SLGHDPDSFE
250 260 270 280 290 300
FSTLGGWLAT CSSGHQSDKY GDIEDMAVSF RTVTPTGTLE LRNGARSGAG INYKHIILGS
310 320 330 340 350 360
EGTLGIITEA VMKVHAVPQA VEYYGFLFPT FAHAVSALQQ IRSSEVIPTM IRVYDPEETQ
370 380 390 400 410 420
LSFAWKPSKG AVSEFTSAMV KKYLHYIRSF DFKNVCLSII GFEGPKKVVD FHRTSVFDIL
430 440 450 460 470 480
SKNAAFGLGS APGKTWAEKR YDLPYIRDFL LDHNMWVDVA ETTVSYANLQ TLWKDAKQTF
490 500 510 520 530 540
VKHFKDQGIP AWICAHISHT YTNGVCLYFI FASKQNENKD MAQYIEAKKL MTDIIFKYGG
550 560 570 580 590 600
SLSHHHGVGY EHVPWMTRYA TRGWINVYRS LKETIDPKDI CNPRKLIPTI KEENNKEPFL
610
FDVVNVKYPK L