O94756
Gene name |
meu14 (SPBC1347.03) |
Protein name |
Meiotic expression up-regulated protein 14 |
Names |
|
Species |
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
KEGG Pathway |
spo:SPBC1347.03 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O94756
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O94756-F1 | Predicted | AlphaFoldDB |
No variants for O94756
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O94756 | |||||
No associated diseases with O94756
No regional properties for O94756
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for O94756 | |||
Functions
6 GO annotations of cellular component
| Name | Definition |
|---|---|
| eisosome filament | A filamentous cortical structure formed, in S. pombe, by the eisosome component Pil1. |
| meiotic spindle pole body | The microtubule organizing center that forms as part of the meiotic cell cycle; functionally homologous to the animal cell centrosome. |
| nuclear membrane | Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
| prospore membrane leading edge | The region of the prospore membrane that extends to surround the spore nucleus; coated with specific proteins that are thought to play a role in prospore membrane organization. |
| prospore membrane spindle pole body attachment site | The region of the prospore membrane to which the spindle pole body (SPB) is anchored; the prospore membrane extends from the SPB attachment site to surround the spore nucleus. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| lipid binding | Binding to a lipid. |
5 GO annotations of biological process
| Name | Definition |
|---|---|
| ascospore-type prospore-specific spindle pole body remodeling | A spindle pole body (SPB) organization process that takes place during the second meiotic division during ascospore formation and results in the structural reorganization of the SPB; includes the recruitment of sporulation-specific proteins to the outer plaque to form the meiotic outer plaque (MOP). |
| eisosome assembly | The aggregation, arrangement and bonding together of a set of components to form an eisosome, a cell part that is composed of the eisosome membrane and eisosome filaments. The eisosome membrane, also called the MCC domain, is a furrow-like plasma membrane sub-domain with associated integral transmembrane proteins. The eisosome filaments form a scaffolding lattice on the cytoplasmic face of the membrane. |
| endocytosis | A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle. |
| lipid droplet localization to prospore membrane leading edge | Any process in which a lipid droplet is transported to, or maintained to the prospore membrane leading edge. |
| negative regulation of protein kinase activity | Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase activity. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MPKSSNLKMQ | RKGSLRENGL | VKGLNKNKFS | ISKLKELSHA | DDSRKSHRII | RSGKSSGEAY |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KQAGKGLMNL | GNHLSDWGAK | SSNLSLNDIS | DKIGVLVSEL | GETEIEFVKA | FNENRIKFKA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| IRAMEDSIAP | SRAHRQRLIS | SIEREEERDP | LSPKLTDLQN | QLVRTEAENL | VGEMQLDNTS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| REVFKSSFQG | LMDAFQLRAQ | KQMTLSYYAS | QLAELINDEV | AYPGDNPAAY | SQKYATQIMH |
| 250 | 260 | 270 | 280 | 290 | 300 |
| QCVESMARLL | APVTSETTEH | VGSDCEFTRK | SSSSVEFSDH | SQDSGDPSQQ | NILQVKNVQA |
| 310 | 320 | 330 | |||
| VLSIPEAESY | KAQLLSSIAE | EQKKKELQAK | STVFL |