O94744

PR
Gene name
git3 (SPCC1753.02c)
Protein name
Glucose receptor protein git3
Names
Glucose-insensitive transcription protein 3
Species
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
KEGG Pathway
spo:SPCC1753.02c
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

190-391 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O94744

Entry ID Method Resolution Chain Position Source
AF-O94744-F1 Predicted AlphaFoldDB

No variants for O94744

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O94744

No associated diseases with O94744

1 regional properties for O94744

Type Name Position InterPro Accession
domain Glucose receptor Git3, N-terminal 29 - 219 IPR023041

Functions

Description
EC Number
Subcellular Localization
  • Membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
G protein-coupled glucose receptor activity Combining with an extracellular glucose molecule and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
G protein-coupled receptor activity Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.

3 GO annotations of biological process

Name Definition
adenylate cyclase-activating G protein-coupled receptor signaling pathway A G protein-coupled receptor signaling pathway in which the signal is transmitted via the activation of adenylyl cyclase activity and a subsequent increase in the intracellular concentration of cyclic AMP (cAMP).
adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway An adenylate cyclase-activating G protein-coupled receptor signaling pathway initiated by glucose binding to its receptor on the surface of the target cell, and ending with the regulation of a downstream cellular process.
negative regulation of induction of conjugation with cellular fusion Any process that stops, prevents, or reduces the frequency or rate of initiation of conjugation with cellular fusion.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLHLDYTFNV SDATSTSSII IVSRRELANL RIMVIIASAI SIVFSLIAIF WRWSRRRTIR
70 80 90 100 110 120
EQFHIALFSV LFIRSIVQMI HPCLALSDPF FWAPKHRCFT IGFFLLVLVR MTDYWIFINI
130 140 150 160 170 180
LHNALLVLFP HVDTERRGLY RFRHTVFTLS FVIPLTIGGL AFTNKRNTFV NLQTRCYLPY
190 200 210 220 230 240
TPVRFMFGLN WSFDYALSIA IIALQTCMFI SIRRKIKRFK KYSHQQTNVF DTLNVIDSYP
250 260 270 280 290 300
TAPDQVALPP FPDTNSTLTY TPSNSQSIYS SQSQPSPYSR PLLSSVHPNL PPGSQSTPAN
310 320 330 340 350 360
LNQSGIHFEQ DFRDSPNRTN GLEDHTSFKL SSPLTSDEDG ASSVLAAYGN DMQDDPLLKQ
370 380 390 400 410 420
RKRILSQSKF LFAYPAIFIF MWILPQIQII VILAQPLHCS GSCKRFAFVA VFADNFVAIF
430 440 450 460
IALSDFIWIC YRGYTYLKER DSSKSYWDQI KELTLKWWRG KFGEEK