O94683
Gene name |
rrp7 (SPBC776.17) |
Protein name |
Ribosomal RNA-processing protein 7 |
Names |
|
Species |
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
KEGG Pathway |
spo:SPBC776.17 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O94683
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O94683-F1 | Predicted | AlphaFoldDB |
No variants for O94683
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O94683 | |||||
No associated diseases with O94683
1 regional properties for O94683
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Ribosomal RNA-processing protein 7, C-terminal domain | 124 - 238 | IPR024326 |
5 GO annotations of cellular component
| Name | Definition |
|---|---|
| CURI complex | A protein complex that is involved in the transcription of ribosomal genes. In Saccharomyces this complex consists of Ckb2p, Utp22p, Rrp7p and Ifh1p. |
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| nucleolus | A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| UTP-C complex | A protein complex that forms a subcomplex of the 90S preribosome. In S. cerevisiae, it is composed of Rrp7p, Utp22p, Ckb1p, Cka1p, Ckb2p and Cka2p. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| ribosomal small subunit assembly | The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the small ribosomal subunit. |
| rRNA processing | Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MDKLKEKGFV | KLEIYLENKK | RLHSIFLKED | TEDVEKKSLY | LINVPITTTE | KILKRAISQL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| GGRIVNIYPN | ISGLLKSGTH | LRVKLVEPAE | VKQVIKAASK | KTTSLPWKFT | QHTGLKRYVE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SYDRQFVNPR | VLAESVDSYM | KRVTKKEIAE | KRRLFAMKNQ | PDEDGFVTVV | RSGRAPVGRP |
| 190 | 200 | 210 | 220 | 230 | |
| QDAERQLEKK | KDTGIHKDFY | RFQLREKKKK | ALLDLAHKFE | FDKQRIQQLK | EKRQFKPY |