Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for O94683

Entry ID Method Resolution Chain Position Source
AF-O94683-F1 Predicted AlphaFoldDB

No variants for O94683

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O94683

No associated diseases with O94683

1 regional properties for O94683

Type Name Position InterPro Accession
domain Ribosomal RNA-processing protein 7, C-terminal domain 124 - 238 IPR024326

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Nucleus, nucleolus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

5 GO annotations of cellular component

Name Definition
CURI complex A protein complex that is involved in the transcription of ribosomal genes. In Saccharomyces this complex consists of Ckb2p, Utp22p, Rrp7p and Ifh1p.
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
UTP-C complex A protein complex that forms a subcomplex of the 90S preribosome. In S. cerevisiae, it is composed of Rrp7p, Utp22p, Ckb1p, Cka1p, Ckb2p and Cka2p.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
ribosomal small subunit assembly The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the small ribosomal subunit.
rRNA processing Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDKLKEKGFV KLEIYLENKK RLHSIFLKED TEDVEKKSLY LINVPITTTE KILKRAISQL
70 80 90 100 110 120
GGRIVNIYPN ISGLLKSGTH LRVKLVEPAE VKQVIKAASK KTTSLPWKFT QHTGLKRYVE
130 140 150 160 170 180
SYDRQFVNPR VLAESVDSYM KRVTKKEIAE KRRLFAMKNQ PDEDGFVTVV RSGRAPVGRP
190 200 210 220 230
QDAERQLEKK KDTGIHKDFY RFQLREKKKK ALLDLAHKFE FDKQRIQQLK EKRQFKPY