O94659

PR
Gene name
nog1 (SPBC651.01c, SPBC725.18c)
Protein name
Probable nucleolar GTP-binding protein 1
Names
Species
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

465-642 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

11 structures for O94659

Entry ID Method Resolution Chain Position Source
8ESQ EM 280 A b 1-642 PDB
8ESR EM 320 A b 1-642 PDB
8ETC EM 310 A b 1-642 PDB
8ETG EM 340 A b 1-642 PDB
8ETH EM 380 A b 1-642 PDB
8ETI EM 370 A b 1-642 PDB
8ETJ EM 320 A b 1-642 PDB
8EUP EM 310 A b 1-642 PDB
8EUY EM 300 A b 1-642 PDB
8EV3 EM 300 A b 1-642 PDB
AF-O94659-F1 Predicted AlphaFoldDB

No variants for O94659

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O94659

No associated diseases with O94659

No regional properties for O94659

Type Name Position InterPro Accession
No domain, repeats, and functional sites for O94659

Functions

Description
EC Number
Subcellular Localization
  • Nucleus, nucleolus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
mitotic spindle A spindle that forms as part of mitosis. Mitotic and meiotic spindles contain distinctive complements of proteins associated with microtubules.
nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
RNA binding Binding to an RNA molecule or a portion thereof.

2 GO annotations of biological process

Name Definition
ribosomal large subunit biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a large ribosomal subunit; includes transport to the sites of protein synthesis.
ribosomal subunit export from nucleus The directed movement of a ribosomal subunit from the nucleus into the cytoplasm.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MATAVFKNIT PIPDVNTFLD VVLSRTQRKT PTVIRSGFKI SRIRGFYGRK VKFTQDTITE
70 80 90 100 110 120
KLDSILQEFP KLNDIHPFHA DLLNILYDRD HLKIALSQLS TAKHLVENVA RDYIRLLKYG
130 140 150 160 170 180
DSLYRCKQLK RAALGRMATI IKRQKSSLEF LEQVRQHLSR LPAIDPNTRT LLVCGYPNVG
190 200 210 220 230 240
KSSFMNKVTR AQVDVQPYAF TTKSLFVGHF DYKYLRWQVI DTPGILDHPL EQMNTIEMQS
250 260 270 280 290 300
ITAMAHLRSA VLYFMDLSEM CGYSVAAQVK LYHSIKPLFA NKVTILVLNK IDAMRPEDLD
310 320 330 340 350 360
QKNQELLQTI IDDGNVKVVQ TSCVQDIGVM DVRTTACEAL LAARVEQKLK GSRVNNVLNR
370 380 390 400 410 420
IHLAEPAARD EVARPACIPD SVKTRRAYDA NDPNRRILAR DIEAANGGAG VYNVELRDKY
430 440 450 460 470 480
ILQDPSWKYD RMPELLDGKN VADFVDPEIE AKLLALDEEE ERLEREGYYD SDQEIEDADE
490 500 510 520 530 540
EEVLEKASRI REKNKLTMLA ARQKKIKNRP VLPRTAGIRT LDELQSSLQS AGLPSDSIEE
550 560 570 580 590 600
RARSRARTAA ANEMADGSGV DLLMNEGEEI RSKSIAPRSQ SNRRESGVHA EGARSYADRL
610 620 630 640
ARVKQIHRNR MARASESDRH VIAAKPKHLL SGKRGNGKTQ RR