O94621
Gene name |
usp109 (SPBC1289.12) |
Protein name |
U1 snRNP-associated protein usp109 |
Names |
|
Species |
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
KEGG Pathway |
spo:SPBC1289.12 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O94621
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O94621-F1 | Predicted | AlphaFoldDB |
No variants for O94621
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O94621 | |||||
No associated diseases with O94621
3 regional properties for O94621
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | RNA recognition motif domain | 3 - 79 | IPR000504-1 |
| domain | RNA recognition motif domain | 86 - 162 | IPR000504-2 |
| domain | RNA recognition motif domain | 189 - 259 | IPR000504-3 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| U1 snRNP | A ribonucleoprotein complex that contains small nuclear RNA U1, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U1 snRNP, most of which remain associated with the U1 snRNA both while the U1 snRNP is free or assembled into a series of spliceosomal complexes. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| mRNA binding | Binding to messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| mRNA 5'-splice site recognition | Recognition of the intron 5'-splice site by components of the assembling spliceosome. |
| mRNA splice site selection | Selection of a splice site by components of the assembling spliceosome. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSTSLWLNNL | EEWMNEDYIR | AIFENVRKVN | YYEDGESGAI | LKTCCIEFES | QDAARNALER |
| 70 | 80 | 90 | 100 | 110 | 120 |
| QSTQRLISGN | PISLDVVPEW | QKPSYYMLFI | SNIDPEVSEN | DIKYLFQRYN | FISARVLRCV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DGTSTSIAFI | WLANESDIQN | AQVEMQGAFC | LKRSILVHSV | KSDKNTYLSS | PGFYGTPQPL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| NQFTDPNNTA | VYVHQLPENI | TTQELRSYFL | HFGEILYTQV | NNNSGRIVFA | QRYFAEQAIN |
| 250 | 260 | 270 | 280 | 290 | 300 |
| EMNNFPLHGV | RIQLSWARPP | SMALLPSKQS | TYWPALAAPV | YPSMKDVPNN | PFTPFSPINP |
| 310 | 320 | 330 | 340 | 350 | 360 |
| YYAKSWNHTA | SAPLLPPGLK | NGSDYPYLSV | PPDILNDSYL | AMCEAVNSRL | DAESTMLLPV |
| HYSQA |