O94570

PR
Gene name
SPBC1773.13
Protein name
Aromatic amino acid aminotransferase C1773.13
Names
Species
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
KEGG Pathway
spo:SPBC1773.13
EC number
2.6.1.57: Transaminases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-54 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O94570

Entry ID Method Resolution Chain Position Source
AF-O94570-F1 Predicted AlphaFoldDB

No variants for O94570

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O94570

No associated diseases with O94570

1 regional properties for O94570

Type Name Position InterPro Accession
domain Aminotransferase, class I/classII 78 - 448 IPR004839

Functions

Description
EC Number 2.6.1.57 Transaminases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

5 GO annotations of molecular function

Name Definition
2-aminoadipate transaminase activity Catalysis of the reaction: 2-oxoglutarate + L-2-aminoadipate = 2-oxoadipate + L-glutamate.
aromatic-amino-acid:2-oxoglutarate aminotransferase activity Catalysis of the reaction: an aromatic amino acid + 2-oxoglutarate = an aromatic oxo acid + L-glutamate.
L-phenylalanine:2-oxoglutarate aminotransferase activity Catalysis of the reaction: L-phenylalanine + 2-oxoglutarate = phenylpyruvate + L-glutamate.
pyridoxal phosphate binding Binding to pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.
transaminase activity Catalysis of the transfer of an amino group to an acceptor, usually a 2-oxo acid.

4 GO annotations of biological process

Name Definition
alpha-amino acid metabolic process The chemical reactions and pathways involving an alpha-amino acid.
aromatic amino acid family catabolic process The chemical reactions and pathways resulting in the breakdown of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan).
lysine biosynthetic process via aminoadipic acid The chemical reactions and pathways resulting in the formation of lysine by the aminoadipic pathway.
tyrosine biosynthetic process The chemical reactions and pathways resulting in the formation of tyrosine, an aromatic amino acid, 2-amino-3-(4-hydroxyphenyl)propanoic acid.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MIRNSEDFSH HLSRESKARE KGPFQMLGRI KSSTGIDAIS FSSGLPHPNK FAIRELSIKF
70 80 90 100 110 120
PQLGCFKEEN GTYAKEVNVT FNIKADPSEG LLNFSQSLQY GQCQGISELV GFIKEHIRRI
130 140 150 160 170 180
HAPRYENWDI KMSNGNTSGL EYCLRLLVNY GDHVLTEKYT YPAAITAMRA LGVQFVSVDM
190 200 210 220 230 240
DSEGMLPESL EEIMRDWDIS LGPRPHVLYT VPTGQNPTGS TLSLSRRKKL LALARKYDII
250 260 270 280 290 300
IVEDEPYYFL QMEDYNGSLN PAQQKCDGST FLKSLVPSLL SLDTEGRVLR LDSFSKLIAP
310 320 330 340 350 360
GTRLGYITGN SMFIDHITRI AEVCTESPSG ICQSVLYAML HNWGQEGFCA WLQELQYSYT
370 380 390 400 410 420
VRRNAFLNVA NKYLPNSVCI YHVPRAGLFL WVELNLNHYR FSDTKKSVSQ IEMEIFLALV
430 440 450 460 470 480
EKGVKTVCGQ FFMANPERST KIFFRFAYSI ADFEDFEEGI KRFTSVINEH FNVESRVRIC
P