O94543

PR
Gene name
SPCC1322.03
Protein name
Uncharacterized membrane protein C1322.03
Names
Species
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
KEGG Pathway
spo:SPCC1322.03
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

603-703 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O94543

Entry ID Method Resolution Chain Position Source
AF-O94543-F1 Predicted AlphaFoldDB

No variants for O94543

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O94543

No associated diseases with O94543

2 regional properties for O94543

Type Name Position InterPro Accession
domain TRP, C-terminal 238 - 565 IPR010308
domain ML-like domain 25 - 184 IPR032800

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Golgi apparatus membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
Golgi apparatus A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways.
Golgi membrane The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
calcium channel activity Enables the facilitated diffusion of a calcium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.

2 GO annotations of biological process

Name Definition
calcium ion import across plasma membrane The directed movement of calcium ions from outside of a cell, across the plasma membrane and into the cytosol.
transmembrane transport The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKPRPYSVFL FLHIVFYSLL SAVNGSPSLD YFETCSNFVP RAGIPTFSPY AVIKNFDEVN
70 80 90 100 110 120
RMYYIQVVGN LSGVITIVGG NGSHIHAASV YSETYALGKL VTSNTTKLCD VVMDPHSFEV
130 140 150 160 170 180
PIKCPWAAGS AAFMVKVPFK STLSDYSKYE LTTLTTRVIV VDGTPEKNVI TCMKFGLSTT
190 200 210 220 230 240
LYYFYPVISY LVVVSLAYVS FSIIYALFLN PWTGSLDPFK SIFNFNMDPD ALRLTSLGFF
250 260 270 280 290 300
DFVQYLQFAV STAQVSVMFP KFYINIMAAL SWGTALFRFP IFSEPAEYQF ADFADLSVAS
310 320 330 340 350 360
SSYADYLPKS YGMYSFLDSI GIGTACWLPF LIVMVIYLFA ALFVALLVIF LKWLMSRIFN
370 380 390 400 410 420
ETIAETRWDT WSFIAGSLIR LYFLTYFPTV AYMSFQFVAP PTGYEIIPVL WFIFFGIFIP
430 440 450 460 470 480
VYLYMNLAFV EPSSKLLEDQ TYLHLFGSIY NSFREERVMF WIFPIAVQFM RGITVGVIGS
490 500 510 520 530 540
SGSAQLAIFF ILEVANVVAY AYVRPHFPQT SMNTLNTFIS TMRLITVILM IPLDPRLKVL
550 560 570 580 590 600
GISRDLLAYA ILFIHIMVCI LFLLLSTQRF MEVSARLLGA KSESKGVPLD RPFGWARVFG
610 620 630 640 650 660
INELRRRRLK DPYSNGNTMM FDHSTYNSNE MSVPLTPVSV CSNSLKKDGE AAPPKLFVQT
670 680 690 700 710 720
NCIPPVTQAS SLVPSKNNTA SSSSLMLDSP VTPSSPYSTS QGYSFYRPPK PKSSVRKRDM
730 740 750 760 770 780
DQLRALQLDF LNNKPNLLRH DVNYAVREAD VYHPHVDTSI DSLSQISSQP FEMRPTAIPP
790 800 810 820 830 840
PPKNAFQRAW QIVQSTAKSI WHSDPPKESE KGFVVLRSRP RPNLQKPLPQ LHIEPSRDEQ
850 860
YSMERKKTDD SLAESAWSIP HP