O94536

PR
Gene name
ucp12 (SPCC895.09c)
Protein name
Putative ATP-dependent RNA helicase ucp12
Names
Species
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
KEGG Pathway
spo:SPCC895.09c
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-63 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O94536

Entry ID Method Resolution Chain Position Source
AF-O94536-F1 Predicted AlphaFoldDB

No variants for O94536

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O94536

No associated diseases with O94536

7 regional properties for O94536

Type Name Position InterPro Accession
domain Helicase, C-terminal 797 - 968 IPR001650
conserved_site DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site 698 - 707 IPR002464
domain RWD domain 402 - 504 IPR006575
domain Helicase-associated domain 1001 - 1087 IPR007502
domain DEAD/DEAH box helicase domain 585 - 742 IPR011545
domain DEAD-box helicase, OB fold 1159 - 1257 IPR011709
domain Helicase superfamily 1/2, ATP-binding domain 575 - 765 IPR014001

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
ribonucleoprotein complex A macromolecular complex that contains both RNA and protein molecules.

5 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
mRNA binding Binding to messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
RNA binding Binding to an RNA molecule or a portion thereof.
RNA helicase activity Unwinding of an RNA helix, driven by ATP hydrolysis.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGSKGKKGKS SEVNLETSKN KEKNIKGKKK NSLDPIEKNK QETAGLQTTS RPTAKQLVGG
70 80 90 100 110 120
SSWTGKIPVV LLNEHCQRSK WEKSDVKVRQ TKSKNYIFTS VVLAKKDPKN PSILDHVSLI
130 140 150 160 170 180
PPKSYYENGY FPEKETLVEA RNVGAVYALH RIMSHKSLQH ALPPEHRNIW FDMEKQKKEE
190 200 210 220 230 240
LKNKHSWLYN EDPFKAAKEL QAARASSAAK PPPKASQKNE KVSLTSIKNT SLSHFSKFNF
250 260 270 280 290 300
KYALPIHMSL ENRRSLENLF RNMNTWDILE DTKNLEPDTS IVNDLISLGF RDIHAKEACQ
310 320 330 340 350 360
YCVSLEDALE WLIIHVPEDD LPTRFLPSDY TTGISVQNLN SANLAIHYNA KRISETGYSF
370 380 390 400 410 420
DLCFSTLQTF ENNIQISSEY LQQHLIGESF DGNISLEPNS TEWDDDVSAL QSILDNKVSK
430 440 450 460 470 480
IENGCRVRID YPTSEFGELF VDFRRPARSY PAHIPLMSLS STKRMASYIK LSILKKMVVY
490 500 510 520 530 540
AMDLRGECML SWLYNHLQEN IEDFLQNIGS LLNISAATIG VSLSSQNKSA PTAKKNNSFK
550 560 570 580 590 600
PKLFRRSREL SEKLCNNWSE RVKSPSYQLK VREREKLPAW ESRRKIMDAI QHSQVVVISG
610 620 630 640 650 660
ETGSGKSTQV VQFILDHYLS SGEKDLQTVV CTQPRRISAI SLAERVAFER DTTVGKEVGY
670 680 690 700 710 720
SVHGEKSISK ETLLEFCTTG LLLRRIQQHG LGFLSTLSCV VVDEVHERSI ENDILLTLLK
730 740 750 760 770 780
LVISRIPNLK VILMSATVNS DTFKYYFGNA GHLHIHGRTF PIKDYYIEDF APKLNEDDDE
790 800 810 820 830 840
EDVPRRKKKE YEIDYHLISR LVSSIDAELG SSSGSILVFL PGVSNIARCI REIKSKDGSK
850 860 870 880 890 900
FEVLPLHASL NTSEQRRCFK TYTKRKIICA TNIAETSITI DDVVAVIDSG RVKQIDYDVE
910 920 930 940 950 960
RDLVTFKETW ASRAACQQRR GRAGRVKKGI CYKLYTRGFE EKGMLGQTPP EVLRTALSQV
970 980 990 1000 1010 1020
CLNVVPLVKR FSSAGNSVNQ GSIKKFMNSL IDPPNDATVD LALKKLIQVG ALTVSEDLTG
1030 1040 1050 1060 1070 1080
LGEYLVSLPI DLKLGKLLVF GSIFGYLEPA LTITAILSTK SPFLGDDEAR EIRSKQSQGW
1090 1100 1110 1120 1130 1140
GDVLADARVY HNWLEILETR GVKKTVQWCE EMHLHYTTLQ QIRQNRNELS EAAQLLELTT
1150 1160 1170 1180 1190 1200
KKLTGNFDWY STENLTVLST LIAAALSPNV VKCVYPDKKF VASFSGSLEM EQEARLTKFY
1210 1220 1230 1240 1250 1260
DQNNQRLFIH PSSTMFVNSP NASRCTFVAY EQKVETTKPF LRNCTPINTY GMILLGANDI
1270 1280 1290 1300 1310 1320
LIDPLGKGLI LDQAYCIKAW PKVVILLKML KRCLDASLHE RLESSSGLNY ESEIHQCIRT
LIAGNGV