O94533
Gene name |
elp2 (SPCC895.06) |
Protein name |
Elongator complex protein 2 |
Names |
|
Species |
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
KEGG Pathway |
spo:SPCC895.06 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O94533
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O94533-F1 | Predicted | AlphaFoldDB |
No variants for O94533
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O94533 | |||||
No associated diseases with O94533
14 regional properties for O94533
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| repeat | WD40 repeat | 39 - 84 | IPR001680-1 |
| repeat | WD40 repeat | 89 - 125 | IPR001680-2 |
| repeat | WD40 repeat | 180 - 224 | IPR001680-3 |
| repeat | WD40 repeat | 257 - 296 | IPR001680-4 |
| repeat | WD40 repeat | 315 - 354 | IPR001680-5 |
| repeat | WD40 repeat | 359 - 398 | IPR001680-6 |
| repeat | WD40 repeat | 520 - 564 | IPR001680-7 |
| repeat | WD40 repeat | 567 - 606 | IPR001680-8 |
| repeat | WD40 repeat | 613 - 663 | IPR001680-9 |
| repeat | WD40 repeat | 660 - 702 | IPR001680-10 |
| conserved_site | WD40 repeat, conserved site | 209 - 223 | IPR019775 |
| repeat | G-protein beta WD-40 repeat | 71 - 85 | IPR020472-1 |
| repeat | G-protein beta WD-40 repeat | 209 - 223 | IPR020472-2 |
| repeat | G-protein beta WD-40 repeat | 641 - 655 | IPR020472-3 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| elongator holoenzyme complex | A heterohexameric protein complex composed two discrete heterotrimeric subcomplexes that is involved in modification of wobble nucleosides in tRNA. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| protein transport | The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| tRNA wobble uridine modification | The process in which a uridine in position 34 of a tRNA is post-transcriptionally modified. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MFQYEALHVG | CNRIPTAATW | SSNLGLIYGA | ERLIAVADPF | KEINYLMAGH | SGRINCVCEL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ATNSEYRSPF | ILSGASDKTL | RLWQLEEEYF | TCIKTIELEA | TVNCLCVNEN | LVVCGCSNSS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| CIVYSWNAEQ | RNLTEISRFT | CSEIIPLEFA | IVKLDHGIIL | TVCGSSKKIM | VYGSDSAISS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| FKLKAVLRGH | LDWVRTLSFK | KTSGSTATLA | SGSQDRYIRL | WNISLWGSED | EKVSEEFFES |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VLSNKPVRFT | LGKIDLKIVF | DALLMGHEDW | VMSVDWHPTK | EMILSSSADS | SMIVWEPDTN |
| 310 | 320 | 330 | 340 | 350 | 360 |
| TGIWVVTGRM | GEMASSHGST | TATGSAGGFW | GGLWNPNGNC | VVCWGRTGGW | RLWKQDAGQW |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LQLPSISGHT | KSVKGVAWDP | EGKFYLSAGT | DQTTRLFARF | KKDNAWHEMA | RPQIHGYDLT |
| 430 | 440 | 450 | 460 | 470 | 480 |
| SISCMPSRIG | FLSCADEKVS | RVFKFPKTIV | RLLYRLCDTN | IGEESLPDAA | NVPLLGLSNK |
| 490 | 500 | 510 | 520 | 530 | 540 |
| ATTASETGTV | NAEEVQTPVA | DVIGSLNHPP | FEEHLQRLLL | FPEVEKLFGH | GYEVYACAIS |
| 550 | 560 | 570 | 580 | 590 | 600 |
| NNGNIAATSC | KSQTPEHAVI | RLYETQSWNQ | QQVLKGHSLT | VTTIKFSPDD | RYILSAGRDR |
| 610 | 620 | 630 | 640 | 650 | 660 |
| LVCLHEQAEN | LLDYNNFASI | KAHSRIIWDA | SWAPKEMGYF | FATASRDKFV | KFWKINDNKK |
| 670 | 680 | 690 | 700 | 710 | 720 |
| ICDVAALQFS | DAVTAVDFAP | FFHNDELLLA | VGTEAGKIFI | WRCPRENLTK | WYPTRLPDHM |
| 730 | 740 | 750 | |||
| APMESINQIL | WKPTFETMGL | YSLLIAGEDT | SVRLLNVTLG |