O94524

PR
Gene name
gto2 (SPCC1281.07c)
Protein name
Glutathione S-transferase omega-like 2
Names
Glutathione-dependent dehydroascorbate reductase
Species
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
KEGG Pathway
spo:SPCC1281.07c
EC number
1.8.5.1: With a quinone or similar compound as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-56 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O94524

Entry ID Method Resolution Chain Position Source
AF-O94524-F1 Predicted AlphaFoldDB

No variants for O94524

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O94524

No associated diseases with O94524

4 regional properties for O94524

Type Name Position InterPro Accession
domain Protein kinase domain 36 - 291 IPR000719
domain Serine-threonine/tyrosine-protein kinase, catalytic domain 36 - 283 IPR001245
active_site Serine/threonine-protein kinase, active site 152 - 164 IPR008271
binding_site Protein kinase, ATP binding site 42 - 63 IPR017441

Functions

Description
EC Number 1.8.5.1 With a quinone or similar compound as acceptor
Subcellular Localization
  • Cytoplasm
  • Nucleus
  • Golgi apparatus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
Golgi apparatus A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

2 GO annotations of molecular function

Name Definition
glutathione dehydrogenase (ascorbate) activity Catalysis of the reaction: dehydroascorbate + 2 glutathione = L-ascorbate + glutathione disulfide.
glutathione transferase activity Catalysis of the reaction: R-X + glutathione = H-X + R-S-glutathione. R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group.

2 GO annotations of biological process

Name Definition
cell wall organization A process that results in the assembly, arrangement of constituent parts, or disassembly of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.
cellular oxidant detoxification Any process carried out at the cellular level that reduces or removes the toxicity superoxide radicals or hydrogen peroxide.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSNTHITDWS SKDGEFRRQV SSFRERISPE HKYFQPEKDR YHLYVSYACP WAHRTLIVRK
70 80 90 100 110 120
LKGLENVIPV HVVGWLMGPN GWNFDKENDS TGDPLYNSPY LRNLYFRADP NYNMRFTVPV
130 140 150 160 170 180
LWDSKYNTIV NNESAEIIRM FNDAFNEVIE DEEKRVVDLY PSSLRTKIDE LNDYFYDTVN
190 200 210 220 230 240
NGVYKTGFAT TAEAYEKNVR VVFQGLDRLE QVLKESKGPF LLGDHLTETD VRLYTTIVRF
250 260 270 280 290 300
DPVYVQHFKC NIGTIRHNYP HINQWLKRLY WKHPAFHETT DFKHIKCHYT QSHTQINPLG
310
ITPLGPIPNV EYF