O94480
Gene name |
bmt5 (SPCC1919.13c) |
Protein name |
25S rRNA (uridine-N(3))-methyltransferase |
Names |
|
Species |
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
KEGG Pathway |
spo:SPCC1919.13c |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O94480
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O94480-F1 | Predicted | AlphaFoldDB |
No variants for O94480
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O94480 | |||||
No associated diseases with O94480
1 regional properties for O94480
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | 25S rRNA (uridine-N(3))-methyltransferase BMT5-like | 61 - 226 | IPR019446 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| nucleolus | A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| rRNA (uridine-N3-)-methyltransferase activity | Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N3-methyluridine. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| rRNA base methylation | The addition of a methyl group to an atom in the nucleoside base portion of a nucleotide residue in an rRNA molecule. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGKKARFKEA | RRLQKRNLNN | AIGSSSINSQ | NSLTNDKIGK | GKNKGPTERY | VLPFEKNNRF |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LLLGEGNFSF | AFSLLLHHVS | SEGFVLATSY | DSKEDLKQKY | PDAAEYISKI | EINGGKVMHE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| IDATKLHLHK | KLKTQKFDTI | FWNFPHSGKG | IKDQDRNILD | NQKMLLAFFK | ASKFLLSEKG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VIVITLAETK | PYTLWNLKGL | AKDAGYTSLM | TEKFDSSFYP | EYSHRRTIGW | IDGISERSPW |
| 250 | 260 | 270 | 280 | ||
| KGELRDSRHY | CFVVNGSNIK | PYNQRKEKRK | RSELSDDSSD | SS |