Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for O94478

Entry ID Method Resolution Chain Position Source
AF-O94478-F1 Predicted AlphaFoldDB

No variants for O94478

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O94478

No associated diseases with O94478

2 regional properties for O94478

Type Name Position InterPro Accession
domain SH3 domain 279 - 345 IPR001452
domain BAR domain 2 - 232 IPR004148

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Nucleus
  • Localizes at the barrier septum
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
cell division site The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles.
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
ESCRT-0 complex A protein complex required for the recycling of Golgi proteins, formation of lumenal membranes and sorting of ubiquitinated proteins into those membranes. This complex includes Vps1p and Hse1p in yeast and the Hrs and STAM proteins in mammals.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

1 GO annotations of molecular function

Name Definition
lipid binding Binding to a lipid.

3 GO annotations of biological process

Name Definition
endocytosis A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.
meiotic cell cycle Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions.
protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway The process of directing proteins towards the vacuole that contributes to protein catabolism via the multivesicular body (MVB) pathway.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MVSRFFSWTN EKPLGDQRAH LPDSFLELEQ EIAIREEGLS KLFQATTIWI DSILKKVDGE
70 80 90 100 110 120
DKEKCLACEN LGKVMINHSK ELPQDSSYGI TLSQLGKANL KIGEHQTSLA YKARVCYLDF
130 140 150 160 170 180
LKRYLVQAKD FHSARKKLES RRQAYESLLQ KSFKEKKEDS RLEEDIRLAL YKFEESTEQV
190 200 210 220 230 240
KNRMIALKDV EADQYQQLTE LIVYELNFFK ESTGILNTIF NSQNSLTPQK KIQSSERSVE
250 260 270 280 290 300
NEFLASPMDP SLSKLFTKTT NTEKISPTPF STPKRKSKKE TVFVKAIYSF TGRNEKELDL
310 320 330 340 350 360
HTGDVIQVSE QLGPDWYMGE KVNSKAEKLG NSGMFPVNYC TRIYDLHVQK SHETRSLERA
370 380 390 400 410
RSIRRIVSDD PRDYCSPIKQ SPIQNLKFLD SDNSLLSSQN VEASSQPIKI RKPLPEIPNK