O94447
Gene name |
slm1 (SPAC637.13c) |
Protein name |
Cytoskeletal signaling protein slm1 |
Names |
|
Species |
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
KEGG Pathway |
spo:SPAC637.13c |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O94447
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O94447-F1 | Predicted | AlphaFoldDB |
2 variants for O94447
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| I_4564697_C_T | 232 | V>I | No | Jeffares_SNPs | |
| I_4564119_G_C | 424 | D>E | No | Jeffares_SNPs |
No associated diseases with O94447
5 regional properties for O94447
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | IPT domain | 255 - 339 | IPR002909 |
| conserved_site | Transcription factor COE, conserved site | 162 - 171 | IPR018350 |
| domain | Transcription factor COE, DNA-binding domain | 22 - 248 | IPR032200 |
| domain | Transcription factor COE, helix-loop-helix domain | 341 - 384 | IPR032201 |
| domain | Transcription factor COE, IPT domain | 256 - 340 | IPR038006 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| cell cortex of cell tip | The region directly beneath the plasma membrane at the cell tip. The cell tip is the region at either end of the longest axis of a cylindrical or elongated cell. |
| eisosome | A cell part that is composed of the eisosome membrane or MCC domain, a furrow-like plasma membrane sub-domain and associated integral transmembrane proteins, and the proteins (eisosome filaments) that form a scaffolding lattice on the cytoplasmic face. Eisosomes broadly affect overall plasma membrane organization. |
| mating projection membrane | The portion of the plasma membrane surrounding a mating projection, the projection formed by unicellular fungi in response to mating pheromone. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| phosphatidylinositol binding | Binding to an inositol-containing glycerophospholipid, i.e. phosphatidylinositol (PtdIns) and its phosphorylated derivatives. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| actin fusion focus assembly | The aggregation, arrangement and bonding together of a set of components to form an actin fusion focus. |
| cell-cell fusion | A cellular process in which two or more cells combine together, their plasma membrane fusing, producing a single cell. In some cases, nuclei fuse, producing a polyploid cell, while in other cases, nuclei remain separate, producing a syncytium. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MELSGKSEFP | TRTEIPNQAS | NGDAVPNTDA | YMGLCNSLTY | RFEGWRHLVE | NLIAFFKQLE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| STSKNNAKEY | MKLSKVIVHP | YKDANVFEEH | GIQDIFAALR | DQTAAIASDS | EQISIQLPGT |
| 130 | 140 | 150 | 160 | 170 | 180 |
| IINILELLRE | DLREHCKKIA | AEGTKGVKVV | EKQRAETQKY | LSLLDRALLP | WRASSPPTVN |
| 190 | 200 | 210 | 220 | 230 | 240 |
| IKNDPFIVDR | QVLNCLARQV | QEENNHSVAV | AQLQEFSFRF | EQNLIAKIKD | TVKQFEGMMN |
| 250 | 260 | 270 | 280 | 290 | 300 |
| QTHVKAINHL | QEVVRVSEAQ | TLAGEWTGYA | KREPEFIHGS | VPPRSVDAIK | YPGKNDQPTV |
| 310 | 320 | 330 | 340 | 350 | 360 |
| PIMAGYLIRK | TSFLKKKQRG | FYAFTHSGYL | YEFKSSDSLQ | DPEPEFALYI | PDCLIGRPSE |
| 370 | 380 | 390 | 400 | 410 | 420 |
| KKPKFKITGK | DATKKIFGAR | NDYAFRASNN | TELMRWWEAL | NTHIANVNYI | QPLSNANGPS |
| 430 | 440 | 450 | 460 | 470 | 480 |
| AVSDSDDDDD | DPNDFRPAVE | RQSSTMNTRM | SQPSSAVNTN | RSYGSEQIPS | YADSQGNSGA |
| 490 | |||||
| NNNFIYNASA | TGHNAWNV |