O94417
Gene name |
cwf26 (SPCC1620.10) |
Protein name |
Pre-mRNA-splicing factor cwf26 |
Names |
Complexed with cdc5 protein 26 |
Species |
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
KEGG Pathway |
spo:SPCC1620.10 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O94417
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O94417-F1 | Predicted | AlphaFoldDB |
No variants for O94417
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O94417 | |||||
No associated diseases with O94417
No regional properties for O94417
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for O94417 | |||
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| RES complex | A protein complex that is required for efficient splicing, and prevents leakage of unspliced pre-mRNAs from the nucleus (named for pre-mRNA REtention and Splicing). In Saccharomyces, the complex consists of Ist3p, Bud13p, and Pml1p. |
| U2-type spliceosomal complex | Any spliceosomal complex that forms during the splicing of a messenger RNA primary transcript to excise an intron that has canonical consensus sequences near the 5' and 3' ends. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| mRNA cis splicing, via spliceosome | The joining together, after removal of an intervening sequence composed of one or more introns, of two segments of the same RNA molecule via spliceosomal catalysis to produce an mRNA composed only of exon sequences that all came from the same primary transcript. |
| mRNA splicing, via spliceosome | The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MHSAHMSNAD | YIAKKYLRKD | QGKKKKKKEK | DFVEIQDEDV | AGWDDDNSFS | LVNRELTSLH |
| 70 | 80 | 90 | 100 | 110 | 120 |
| DAPTIVANES | LKDRDIDAIY | QNIEKTTNKP | AQLWKAVGND | EVVESEQQDS | HDAESIPQFG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LLTGKQVTFK | AEERRKREEK | SSNLDEEELR | KSRETVYRDA | TGRRIDLVLA | RKEAKRKLKE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KEEEARRQKE | QQQGVVQVRQ | QKEYLKELER | QKTVPLARYE | DDPEYNKELK | ERSRWNDPAA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SFLTNKPVSS | KATYQGYAPP | NRFNIRPGHR | WDGIIRGNGF | ENKWFQRQNE | RKAQEHEAHM |
| WAIEDM |