Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for O94370

Entry ID Method Resolution Chain Position Source
AF-O94370-F1 Predicted AlphaFoldDB

No variants for O94370

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O94370

No associated diseases with O94370

3 regional properties for O94370

Type Name Position InterPro Accession
repeat Mitochondrial substrate/solute carrier 14 - 96 IPR018108-1
repeat Mitochondrial substrate/solute carrier 102 - 185 IPR018108-2
repeat Mitochondrial substrate/solute carrier 190 - 275 IPR018108-3

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion inner membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of mitochondrial inner membrane The component of the mitochondrial inner membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

1 GO annotations of molecular function

Name Definition
thiamine transmembrane transporter activity Enables the transfer of thiamine from one side of a membrane to the other. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver.

2 GO annotations of biological process

Name Definition
mitochondrial thiamine pyrophosphate transmembrane transport The process in which thiamine pyrophosphate is transported across a mitochondrial membrane, into or out of the mitochondrion.
thiamine pyrophosphate transmembrane transport The process in which thiamine pyrophosphate is transported across a membrane.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGLAKQKDSQ EFAQPVWHYT LAGGISSVIC RFMIAPFDVI KIRMQITQSS LRPVFKETVQ
70 80 90 100 110 120
KEGVRALWRG NVVAELLYLV YGAAEFVAFS KLKHLTENLA MNDHAVNFLC GTSAGIFATL
130 140 150 160 170 180
TSYPLDTMRT KFASYAKTPH MLPATKKIYA EAGIKGFFPG LKFSVIQIGP YAGCFFMFYR
190 200 210 220 230 240
ASEAVLSPLG LALSSTLSGV IAGAGSKAIM FPVDTVVKTL QTFPSNYKSF KDCFLSIYRN
250 260 270 280
SGIKGLYRGL SVSMLKVAPG RAITMLIYEQ TLQGLRTLSS PEA