O94168

PR
Gene name
SNF1
Protein name
Carbon catabolite-derepressing protein kinase
Names
Species
Candida tropicalis (Yeast)
KEGG Pathway
EC number
2.7.11.1: Protein-serine/threonine kinases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-78 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

191-213 (Activation loop from InterPro)

Target domain

52-303 (Protein kinase domain)

Relief mechanism

Assay

References

Autoinhibited structure

Activated structure

1 structures for O94168

Entry ID Method Resolution Chain Position Source
AF-O94168-F1 Predicted AlphaFoldDB

No variants for O94168

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O94168

No associated diseases with O94168

5 regional properties for O94168

Type Name Position InterPro Accession
domain Protein kinase domain 52 - 303 IPR000719
active_site Serine/threonine-protein kinase, active site 170 - 182 IPR008271
domain Carbon catabolite-derepressing protein kinase, ubiquitin-associated domain 326 - 389 IPR013896
binding_site Protein kinase, ATP binding site 58 - 81 IPR017441
domain AMPK, C-terminal adenylate sensor domain 486 - 612 IPR032270

Functions

Description
EC Number 2.7.11.1 Protein-serine/threonine kinases
Subcellular Localization
  • Nucleus membrane ; Peripheral membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nuclear membrane Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
protein serine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate.
protein serine/threonine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.

2 GO annotations of biological process

Name Definition
carbohydrate metabolic process The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
protein phosphorylation The process of introducing a phosphate group on to a protein.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSEQNQGQPD QQHSGDHQHH HHHHHHHHHS QQPAQPIPID PNVNPANRIG RYQIIKTLGE
70 80 90 100 110 120
GSFGKVKLAQ HVGTGQKVAL KIINRKTLAK SDMQGRVERE ISYLRLLRHP HIIKLYDVIK
130 140 150 160 170 180
SKDEIIMVIE FAGKELFDYI VQRGKMPEDE ARRFFQQIIA AVEYCHRHKI VHRDLKPENL
190 200 210 220 230 240
LLDDQLNVKI ADFGLSNIMT DGNFLKTSCG SPNYAAPEVI SGKLYAGPEV DVWSSGVILY
250 260 270 280 290 300
VMLCGRLPFD DEFIPALFKK ISNGVYTLPN YLSPGAKHLL TRMLVVNPLN RITIHEIMED
310 320 330 340 350 360
EWFKQDMPDY LLPPDLSKIK TSKIDIDEDV ISALSVTMGY DRDEIISVIE KANREAAAGG
370 380 390 400 410 420
ATPTNQSKST NEVLDAYLLM KENHTLVKDL KKSKSENIES FLSLSPPPSS SFPNPGSTSS
430 440 450 460 470 480
APGVQQSLTY QTLATVPDLS TLPNSTIAIL PTSLPSIHRA YMMETKVNDP QQQIPAPQPT
490 500 510 520 530 540
KKLKTRWHFG IRSRSYPLDV MGEIYRALKN LGAEWAKPTE EELWTIRVRW KYDSTPQLRV
550 560 570 580 590 600
WQRTNLMKMQ IQLFQLEPNN YLVDFKFDGW EQTSDESKND ASLDYKQQDL DEVGSFSAYP
610
FLHLATRLIM ELAVNSQSG