O93796
Gene name |
TEF3 (CAGL0B03487g) |
Protein name |
Elongation factor 3 |
Names |
EF-3 |
Species |
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata) |
KEGG Pathway |
cgr:CAGL0B03487g |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O93796
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O93796-F1 | Predicted | AlphaFoldDB |
No variants for O93796
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O93796 | |||||
No associated diseases with O93796
10 regional properties for O93796
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | ABC transporter-like, ATP-binding domain | 426 - 641 | IPR003439-1 |
| domain | ABC transporter-like, ATP-binding domain | 667 - 993 | IPR003439-2 |
| domain | AAA+ ATPase domain | 455 - 616 | IPR003593-1 |
| domain | AAA+ ATPase domain | 693 - 970 | IPR003593-2 |
| domain | Elongation Factor 3, ABC2 domain, chromodomain-like insertion | 794 - 861 | IPR015688 |
| conserved_site | ABC transporter-like, conserved site | 544 - 558 | IPR017871-1 |
| conserved_site | ABC transporter-like, conserved site | 897 - 911 | IPR017871-2 |
| repeat | HEAT, type 2 | 91 - 129 | IPR021133-1 |
| repeat | HEAT, type 2 | 171 - 209 | IPR021133-2 |
| domain | Elongation factor 3, four helical bundle domain | 336 - 411 | IPR040533 |
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasmic stress granule | A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress. |
| cytosolic ribosome | A ribosome located in the cytosol. |
| fungal biofilm matrix | An extracellular matrix lying external to fungal cells. The fungal biofilm matrix consists of polysaccharides, proteins, lipids, and nucleic acids. Fungal biofilms mediate adherence to host tissues, and provide protection from host immune defenses. |
| polysomal ribosome | A ribosome bound to mRNA that forms part of a polysome. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATP hydrolysis activity | Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. |
| RNA binding | Binding to an RNA molecule or a portion thereof. |
| translation elongation factor activity | Functions in chain elongation during polypeptide synthesis at the ribosome. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| cytoplasmic translation | The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein. |
| negative regulation of protein kinase activity | Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase activity. |
| translational termination | The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code). |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTDSDQSLKV | LEELFKNLSV | ATADNRVEAA | QEVASFLNGN | IIEHDIPEKF | FEELAKAVKD |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KKTSANFLEA | VAHIANEANL | SPSVEPFVIT | LVPEICAKAG | DKDKDVQAVA | SKTLVAISKA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| INPVAIKAYL | PHLTKSLETT | NKWQEKVSVL | AAISALVDAA | KEQVALRMPE | LIPVLSETMW |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DTKKEVKEAA | TATMTKATET | VDNKDIERFI | PQLISCIADP | KQVPETVHLL | GATTFVAEVT |
| 250 | 260 | 270 | 280 | 290 | 300 |
| PATLSIMVPL | LSRGLAERET | SIKRKAAVII | DNMCKLVEDP | QVVAPFLDKL | LPGLKNNYAT |
| 310 | 320 | 330 | 340 | 350 | 360 |
| IADPEAREVT | LRGLKTLRRV | GNVTEDDVLP | EISHAGDIET | TLGVINELLK | GENVAPRFKI |
| 370 | 380 | 390 | 400 | 410 | 420 |
| VVEYIAAMAG | DLIDERVIDQ | QAWFTHITPY | MTIFMHERNA | KDVLDEFRKR | AVDNIPVGPN |
| 430 | 440 | 450 | 460 | 470 | 480 |
| FDDEEDEGED | LCNCEFSLAY | GAKILLNKTQ | LRLKRGRRYG | LCGPNGAGKS | TLMRAIANGQ |
| 490 | 500 | 510 | 520 | 530 | 540 |
| VDGFPTPEEC | MTVYVEHDID | GTHADTSVLD | FVVSSEVGTK | EAITAKLVEF | GFTEEMINMP |
| 550 | 560 | 570 | 580 | 590 | 600 |
| ISSLSGGWKM | KLALARAVLK | NADILLLDEP | TNHLDTVNVA | WLVNYLNTCG | ITSVIVSHDS |
| 610 | 620 | 630 | 640 | 650 | 660 |
| GFLDNVCQYI | IHYEGLKLRK | YKGNLSEFVK | KCPTAQSYYE | LGASDLEFKF | PEPGYLEGVK |
| 670 | 680 | 690 | 700 | 710 | 720 |
| TKQKAIVKVS | NMTFQYPGTS | KPQISDISFQ | CSLSSRIAVI | GPNGAGKSTL | INVLTGELLP |
| 730 | 740 | 750 | 760 | 770 | 780 |
| TSGEVYTHEN | CRIAYIKQHA | FAHIESHLDK | TPSEYIQWRF | QTGEDRETMD | RANRQINEND |
| 790 | 800 | 810 | 820 | 830 | 840 |
| AEAMNKIFKI | EGTPRRIAGI | HARRKFKNTY | EYECSFLLGE | NIGMKSERWV | PMMSVDNAWI |
| 850 | 860 | 870 | 880 | 890 | 900 |
| PRGELVESHS | KMVAEVDMKE | ALASGQFRPL | TRKEIEEHCA | MLGLDAELVS | HSRIRGLSGG |
| 910 | 920 | 930 | 940 | 950 | 960 |
| QKVKLVLAAC | SWQRPHLIVL | DEPTNYLDRD | SLGALSKALK | AFEGGVIIIT | HSAEFTKNLT |
| 970 | 980 | 990 | 1000 | 1010 | 1020 |
| EEVWAVKDGK | MTPSGHNWVS | GQGAGPRIEK | KEDEEDKFDA | MGNKIAGGKK | KKKLSSAELR |
| 1030 | 1040 | ||||
| KKKKERMKKK | KELGDAYVSS | DDEDF |