O93654
Gene name |
trf2 (Ta0301) |
Protein name |
Tricorn protease-interacting factor F2 |
Names |
|
Species |
Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165) |
KEGG Pathway |
tac:Ta0301 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O93654
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O93654-F1 | Predicted | AlphaFoldDB |
No variants for O93654
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O93654 | |||||
No associated diseases with O93654
2 regional properties for O93654
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Glycoside hydrolase, family 37, conserved site | 157 - 170 | IPR018232-1 |
| conserved_site | Glycoside hydrolase, family 37, conserved site | 453 - 462 | IPR018232-2 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| aminopeptidase activity | Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain. |
| metallopeptidase activity | Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions. |
| zinc ion binding | Binding to a zinc ion (Zn). |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| proteolysis | The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MNPGIEKYEI | RFDFDLKDFT | YTSHERIHLA | GDWKDIKLDA | VRLSVDKVTC | NGQPMRFETG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| QDTVTVKGSF | HDKDVIDIDF | HAKVSDTLMG | LYLSRTKEGT | MITTQFESNG | ARMAFPCVDH |
| 130 | 140 | 150 | 160 | 170 | 180 |
| PAYKAVFAIT | VVIDKDYDAI | SNMPPKRIEV | SERKIVEFQD | TPKMSTYLLY | IGVGKFKYAT |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DKYRDIDLIL | VSLKDIKSKY | PLEIARKSIE | FYESYFGIPY | ALPKMHLISV | PEFGAGAMEN |
| 250 | 260 | 270 | 280 | 290 | 300 |
| WGAITFREVA | LMATENSGSI | MKQNAAITIA | HEIAHQWFGD | LVTMKWWNDL | WLNESFATFM |
| 310 | 320 | 330 | 340 | 350 | 360 |
| SYKTVDSFSK | QWDVFADFIR | SETGGALRSD | SLKNTHPIEV | DVKDPDEISQ | IFDEISYGKG |
| 370 | 380 | 390 | 400 | 410 | 420 |
| ASILRMIEDY | AGYEEFRKGI | SKYLNDHRYG | NAEGSDLWTA | IEDVSGKPVK | RVMEYWIKNP |
| 430 | 440 | 450 | 460 | 470 | 480 |
| GYPVVSVVKS | GNKFRLTQEQ | FFLDGTRGQG | KWPIPLTVMT | KSGKKAMLME | ESAEIEDMVK |
| 490 | 500 | 510 | 520 | 530 | 540 |
| VNVNSSGFYR | VSYDGESFET | VMKNYSKLSN | LDRWGLISDL | YAFLISGRVS | VDDYLARIKG |
| 550 | 560 | 570 | 580 | 590 | 600 |
| FFEDSDHLIV | EEIASQLTGL | YLLKPDSNRI | RETAASYLSR | QVVALGDKQK | GEDDKISKIR |
| 610 | 620 | 630 | 640 | 650 | 660 |
| GIVTQDLAMV | DDHFASDLAR | KFSTLAEDPD | LALAKSIAAA | KAYGISELAS | AADKYTDDEI |
| 670 | 680 | 690 | 700 | 710 | 720 |
| RVRIIAAMGW | CSPSDLKSVF | ELIDKGTIRK | QDMLYVFSNM | PANPKGRDFF | FSNIDRIVAL |
| 730 | 740 | 750 | 760 | 770 | 780 |
| MEHAFEGTGY | TSRILETAIP | YLGLARYEDV | KKKAEQIRKP | SYNVGINKGL | ETLEIVRKLY |
| NKL |