O88834
Gene name |
Shd |
Protein name |
SH2 domain-containing adapter protein D |
Names |
|
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:20420 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O88834
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O88834-F1 | Predicted | AlphaFoldDB |
12 variants for O88834
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs3406894539 | 56 | E>G | No | EVA | |
| rs3389471731 | 75 | V>L | No | EVA | |
| rs3389477818 | 84 | K>M | No | EVA | |
| rs3389430524 | 100 | Y>N | No | EVA | |
| rs3389482366 | 133 | R>S | No | EVA | |
| rs3389473480 | 159 | R>W | No | EVA | |
| rs233500488 | 210 | P>S | No | EVA | |
| rs3389471721 | 225 | W>C | No | EVA | |
| rs3389419801 | 225 | W>R | No | EVA | |
| rs51072388 | 249 | V>I | No | EVA | |
| rs3389438693 | 286 | Q>* | No | EVA | |
| rs212105427 | 306 | L>M | No | EVA |
No associated diseases with O88834
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| phosphotyrosine residue binding | Binding to a phosphorylated tyrosine residue within a protein. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q96IW2 | SHD | SH2 domain-containing adapter protein D | Homo sapiens (Human) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAKWLRDYLN | LGSRRPPPQP | PTPDYTESDI | LRAYREQKDL | DFEDPYEDSN | GRAEPEVTGS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| GDPKYNSPRH | RLIKVEAADM | ARAKALLGSP | GEEPEAETEY | SDPFDAQPQP | PAPNSGYMEP |
| 130 | 140 | 150 | 160 | 170 | 180 |
| YDARSVSSEQ | PSRAVQLYDT | PYEEQATKPE | DGGSSGQSRR | PLEDERPADE | YDQPWEWKKD |
| 190 | 200 | 210 | 220 | 230 | 240 |
| HISRAFAVQF | DGPDWERTPC | STKEPWRPQP | AERVDTALAL | EKQPWFHGPL | SRAEAENLLS |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LCKEGSYLVR | LSETRAQDCI | LSLRSNQGSM | HLKFARTREN | QVVLGQHSGP | FPSIPELVLH |
| 310 | 320 | 330 | 340 | ||
| YSARPLPVQG | AEHLALLYPV | TSSQSSQGPC | TLAAKPERGQ | GDP |