O88668
Gene name |
Creg1 (Creg) |
Protein name |
Protein CREG1 |
Names |
Cellular repressor of E1A-stimulated genes 1 |
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:433375 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O88668
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O88668-F1 | Predicted | AlphaFoldDB |
13 variants for O88668
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs3390930114 | 25 | L>V | No | EVA | |
| rs3388513887 | 44 | R>K | No | EVA | |
| rs3388513487 | 45 | R>* | No | EVA | |
| rs3388513469 | 54 | D>Y | No | EVA | |
| rs230930233 | 98 | E>K | No | EVA | |
| rs3388513346 | 127 | M>T | No | EVA | |
| rs3388514089 | 142 | P>S | No | EVA | |
| rs3388514107 | 145 | P>S | No | EVA | |
| rs257530234 | 148 | V>A | No | EVA | |
| rs222648181 | 168 | R>K | No | EVA | |
| rs3388508934 | 203 | F>L | No | EVA | |
| rs3388513604 | 210 | T>R | No | EVA | |
| rs3388514457 | 220 | Q>* | No | EVA |
No associated diseases with O88668
No regional properties for O88668
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for O88668 | |||
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| extracellular space | That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. |
| transcription regulator complex | A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| regulation of DNA-templated transcription | Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAARAPELAR | SLLAALLAPA | LVALLVSPAS | GRGGRDHGDW | DVDRRLPPLP | PREDGPRVAR |
| 70 | 80 | 90 | 100 | 110 | 120 |
| FVTHVSDWGS | LATISTIKEV | RGWPFADIIS | ISDGPPGEGT | GEPYMYLSPL | QQAVSDLQEN |
| 130 | 140 | 150 | 160 | 170 | 180 |
| PEATLTMSLA | QTVYCRNHGF | DPQSPLCVHI | MMSGTVTKVN | KTEEDYARDS | LFVRHPEMKH |
| 190 | 200 | 210 | |||
| WPSSHNWFFA | KLKISRIWVL | DYFGGPKVVT | PEEYFNVTLQ |