O88101

PR
Gene name
argH
Protein name
Argininosuccinate lyase
Names
ASAL, Arginosuccinase
Species
Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025)
KEGG Pathway
cgl:Cgl1401
EC number
4.3.2.1: Lyases acting on amides, amidines, etc
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

425-477 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O88101

Entry ID Method Resolution Chain Position Source
AF-O88101-F1 Predicted AlphaFoldDB

No variants for O88101

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O88101

No associated diseases with O88101

3 regional properties for O88101

Type Name Position InterPro Accession
conserved_site Fumarate lyase, conserved site 283 - 292 IPR020557
domain Fumarate lyase, N-terminal 15 - 308 IPR022761
domain Argininosuccinate lyase, C-terminal 371 - 443 IPR029419

Functions

Description
EC Number 4.3.2.1 Lyases acting on amides, amidines, etc
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
argininosuccinate lyase activity Catalysis of the reaction: N-(L-arginino)succinate = fumarate + L-arginine.

1 GO annotations of biological process

Name Definition
arginine biosynthetic process via ornithine The chemical reactions and pathways resulting in the formation of arginine (2-amino-5-guanidinopentanoic acid) via the intermediate compound ornithine.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MEQHGTNEGA LWGGRFSGGP SEAMFALSVS THFDWVLAPY DVLASKAHAK VLHQADLLSD
70 80 90 100 110 120
EDLATMLAGL DQLGKDVADG TFGPLPSDED VHGAMERGLI DRVGPEVGGR LRAGRSRNDQ
130 140 150 160 170 180
VATLFRMWVR DAVRDIALGT TELVDALSAQ AKAHAGAIMP GKTHFQAAQP VLLAHQLLAH
190 200 210 220 230 240
AQPLLRDIDR IRDLDKRLAV SPYGSGALAG SSLKLNPEAI AEELGFDSAA DNSIDATSSR
250 260 270 280 290 300
DFASETAFVL AQLAVDMSRL AEEIIAWCTP EFGYITLSDS WSTGSSIMPQ KKNPDVAELT
310 320 330 340 350 360
RGKSGRLIGN LTGLLATLKA QPLAYNRDLQ EDKEPIVDSV AQLNLLLPAM TGLVSTLTFN
370 380 390 400 410 420
TERMRELAPA GFTLATDLAE WMVRQGVPFR EAHEASGACV RIAESRGVDL IDLTDEELSG
430 440 450 460 470
VDARLTPEVR EVLTIDGAVA SRATRGGTAG VRVAEQRARV DAASTAHAEW ARAGVRR