Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for O86459

Entry ID Method Resolution Chain Position Source
AF-O86459-F1 Predicted AlphaFoldDB

No variants for O86459

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O86459

No associated diseases with O86459

3 regional properties for O86459

Type Name Position InterPro Accession
domain Aminoacyl-tRNA synthetase, class II (D/K/N) 113 - 432 IPR004364
domain OB-fold nucleic acid binding domain, AA-tRNA synthetase-type 16 - 94 IPR004365
domain Aminoacyl-tRNA synthetase, class II 131 - 438 IPR006195

Functions

Description
EC Number 2.6.1.1 Transaminases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
glutamate-prephenate aminotransferase activity Catalysis of the reaction: 2-oxoglutarate + L-arogenate = L-glutamate + prephenate.
L-aspartate:2-oxoglutarate aminotransferase activity Catalysis of the reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.
pyridoxal phosphate binding Binding to pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.

2 GO annotations of biological process

Name Definition
alpha-amino acid metabolic process The chemical reactions and pathways involving an alpha-amino acid.
biosynthetic process The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAFLADALSR VKPSATIAVS QKARELKAKG RDVIGLGAGE PDFDTPDNIK KAAIDAINRG
70 80 90 100 110 120
ETKYTPVSGI PELRKAIAAK FKRENGLDYS WEQTIVGTGG KQILFNAFMA TLNPGDEVSI
130 140 150 160 170 180
PAPYWVSYPE MVALCGGTRF FVSATQEHNF KLQAADLEKA ITPKTKWFIF NSPSNPTGAA
190 200 210 220 230 240
YTHDELKALT DVLMKNPQVW VLTDDMYEHL TYGDFKFVTP VEVEPQLYDR TLTMNGVSKA
250 260 270 280 290 300
YAMTGWRIGY AAGPIQLIKA MDMIQGQQTS GATSIAQWAA VEALNGTQDF IPENKKIFEG
310 320 330 340 350 360
RRDLVVSMLN QAKGIVCPVP EGAFYVYPSC KGLIGKTAPS GKVIETDEDF VSELLESEGV
370 380 390
AVVHGSAFGL GPNFRISYAT SEEQLEEACR RIQRFCGACK