O86090

PR
Gene name
ppk
Protein name
Polyphosphate kinase
Names
ATP-polyphosphate phosphotransferase, Polyphosphoric acid kinase
Species
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
KEGG Pathway
stm:STM2501
EC number
2.7.4.1: Phosphotransferases with a phosphate group as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

34-107 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O86090

Entry ID Method Resolution Chain Position Source
AF-O86090-F1 Predicted AlphaFoldDB

No variants for O86090

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O86090

No associated diseases with O86090

5 regional properties for O86090

Type Name Position InterPro Accession
domain Phospholipase D/Transphosphatidylase 430 - 464 IPR001736
domain Polyphosphate kinase middle domain 119 - 321 IPR024953
domain Polyphosphate kinase N-terminal domain 7 - 109 IPR025198
domain Polyphosphate kinase C-terminal domain 2 503 - 674 IPR025200
domain Polyphosphate kinase, C-terminal domain 1 333 - 495 IPR041108

Functions

Description
EC Number 2.7.4.1 Phosphotransferases with a phosphate group as acceptor
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
polyphosphate kinase complex A protein complex that possesses polyphosphate kinase activity.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
metal ion binding Binding to a metal ion.
polyphosphate kinase activity Catalysis of the reaction: ATP + phosphate(n) = ADP + phosphate(n+1).

3 GO annotations of biological process

Name Definition
organophosphate metabolic process The chemical reactions and pathways involving organophosphates, any phosphate-containing organic compound.
phosphorylation The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.
polyphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of a polyphosphate, the anion or salt of polyphosphoric acid.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGQEKLYIEK ELSWLAFNER VLQEAADKSN PLIERMRFLG IYSNNLDEFY KVRFAELKRR
70 80 90 100 110 120
IIISEEQGSN SHSRHLLGKI QSRVLKADQE FDGLYNELLL EMARNQIFLI NERQLSVNQQ
130 140 150 160 170 180
SWLRHYFKHY LRQHITPILI NRETDLVQFL KDDYTYLAVE IIRGDTINYA LLEIPSDKVP
190 200 210 220 230 240
RFVNLPPETP RRRKPMILLD NILRYCLDDI FKGFFDYDAL NAYSMKMTRD AEYDLVHEME
250 260 270 280 290 300
SSLMELMSSS LKQRLTAEPV RFVYQRDMPA ALVDVLREKL TISRYDSIVP GGRYHNFKDF
310 320 330 340 350 360
INFPNVGKAN LVNKPLPRLR HLWFDKEKFR NGFDAIRERD VLLYYPYHTF EHVLELLRQA
370 380 390 400 410 420
SFDPSVLAIK INIYRVAKDS RIIDSMIHAA HNGKKVTVVV ELQARFDEEA NIHWAKRLTE
430 440 450 460 470 480
AGVHVIFSAP GLKIHAKLFL ISRKEGDDVV RYAHIGTGNF NEKTARLYTD YSLLTADARI
490 500 510 520 530 540
TNEVRRVFNF IENPYRPVTF DYLMVSPQNS RRLLYEMIDR EIANAQQGLP SGITLKLNNL
550 560 570 580 590 600
VDKGLVDRLY AASGSGVQVN LLVRGMCSLI PQLEGISDNI RAISIVDRYL EHDRVYIFEN
610 620 630 640 650 660
GGDKQVWLSS ADWMTRNIDY RIEVATPILD PRLKQRVLDI IDILFSDTVK ARFIDKELSN
670 680
RYVPRGNRRK VQAQLAIYDY IKSLEQPD