O86034
Gene name |
bdhA (RB1136, SMb21010) |
Protein name |
D-beta-hydroxybutyrate dehydrogenase |
Names |
BDH, 3-hydroxybutyrate dehydrogenase, 3-HBDH |
Species |
Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti) |
KEGG Pathway |
sme:SM_b21010 |
EC number |
1.1.1.30: With NAD(+) or NADP(+) as acceptor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
2 structures for O86034
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 3V2H | X-ray | 300 A | A/B | 1-258 | PDB |
| AF-O86034-F1 | Predicted | AlphaFoldDB |
No variants for O86034
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O86034 | |||||
No associated diseases with O86034
1 regional properties for O86034
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Short-chain dehydrogenase/reductase, conserved site | 140 - 168 | IPR020904 |
Functions
| Description | ||
|---|---|---|
| EC Number | 1.1.1.30 | With NAD(+) or NADP(+) as acceptor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| 3-hydroxybutyrate dehydrogenase activity | Catalysis of the reaction: (R)-3-hydroxybutanoate + NAD(+) = acetoacetate + H(+) + NADH. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTKTAVITGS | TSGIGLAIAR | TLAKAGANIV | LNGFGAPDEI | RTVTDEVAGL | SSGTVLHHPA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| DMTKPSEIAD | MMAMVADRFG | GADILVNNAG | VQFVEKIEDF | PVEQWDRIIA | VNLSSSFHTI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| RGAIPPMKKK | GWGRIINIAS | AHGLVASPFK | SAYVAAKHGI | MGLTKTVALE | VAESGVTVNS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| ICPGYVLTPL | VEKQIPDQAR | TRGITEEQVI | NEVMLKGQPT | KKFITVEQVA | SLALYLAGDD |
| 250 | |||||
| AAQITGTHVS | MDGGWTAQ |