O86028
Gene name |
bhbA |
Protein name |
Methylmalonyl-CoA mutase |
Names |
MCM |
Species |
Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti) |
KEGG Pathway |
sme:SM_b20757 |
EC number |
5.4.99.2: Transferring other groups |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O86028
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O86028-F1 | Predicted | AlphaFoldDB |
No variants for O86028
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O86028 | |||||
No associated diseases with O86028
4 regional properties for O86028
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Methylmalonyl-CoA mutase, alpha chain, catalytic | 26 - 544 | IPR006098 |
| domain | Methylmalonyl-CoA mutase, alpha/beta chain, catalytic | 28 - 540 | IPR006099 |
| domain | Cobalamin (vitamin B12)-binding domain | 580 - 712 | IPR006158 |
| domain | Methylmalonyl-CoA mutase, C-terminal | 580 - 707 | IPR006159 |
Functions
| Description | ||
|---|---|---|
| EC Number | 5.4.99.2 | Transferring other groups |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| cobalamin binding | Binding to cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom. |
| metal ion binding | Binding to a metal ion. |
| methylmalonyl-CoA mutase activity | Catalysis of the reaction: (R)-methylmalonyl-CoA = succinyl-CoA. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTEKTIKDWE | ALAEKELRVS | PEGLVWHTPE | GIDVKPLYTS | DDMSGIGHLN | SLPGFEPFVR |
| 70 | 80 | 90 | 100 | 110 | 120 |
| GPRATMYAGR | PWTVRQYAGF | STAEASNAFY | RRNLAAGQQG | VSVAFDLATH | RGYDSDHPRV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| QGDVGKAGVA | IDSVEDMKIL | FDGIPLDRIS | VSMTMNGAVI | PILASFIVAG | EEQGVSRDKL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SGTIQNDILK | EFMVRNTYIY | PPEPSMRIVA | DIIEYTAKEM | PKFNSISISG | YHMQEAGATL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VQELAFTLAD | GREYVRAALA | KGLNVDDFAG | RLSFFFAIGM | NFFMEAAKLR | AARLLWTRIM |
| 310 | 320 | 330 | 340 | 350 | 360 |
| QEFKPEKASS | LMLRTHCQTS | GVSLQEQDPY | NNIVRTAFEA | MSAVLGGTQS | LHTNSFDEAM |
| 370 | 380 | 390 | 400 | 410 | 420 |
| ALPTDFSARI | ARNTQLILQH | ETGVTKVVDP | LAGSYYVESL | TNELAEKAWG | LIEEVEALGG |
| 430 | 440 | 450 | 460 | 470 | 480 |
| MTKAVNAGLP | KRLIEEAATR | RQAAVDRAEE | VIVGVNKYRL | ENEQPIDILQ | IDNAAVRTAQ |
| 490 | 500 | 510 | 520 | 530 | 540 |
| VKRIEETRRR | RDSQKMKQAL | DALADVARSG | KGNLLAAAVE | AARARATVGE | ITDAMREAFG |
| 550 | 560 | 570 | 580 | 590 | 600 |
| DYTAIPEVVT | DIYGKAYEGD | PELGVLAGRL | GEATKRLGHK | PKIMVAKLGQ | DGHDRGAKVI |
| 610 | 620 | 630 | 640 | 650 | 660 |
| ASAFGDIGFD | VVAGPLFQTP | EEAADLALAE | EVTVIGVSSL | AAGHRTLMPQ | LAEALKKRGG |
| 670 | 680 | 690 | 700 | 710 | |
| EDIIVVCGGV | IPRQDYDYLM | ENGVAAVFGP | GTQVLDAARA | VLDLIEGKRR | NV |