Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O84905
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O84905-F1 | Predicted | AlphaFoldDB |
No variants for O84905
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O84905 | |||||
No associated diseases with O84905
15 regional properties for O84905
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Immunodeficiency lentiviral matrix, N-terminal | 2 - 127 | IPR000071 |
| domain | Reverse transcriptase domain | 631 - 821 | IPR000477 |
| domain | Integrase, C-terminal, retroviral | 1370 - 1417 | IPR001037 |
| domain | Integrase, catalytic core | 1201 - 1351 | IPR001584 |
| domain | Zinc finger, CCHC-type | 392 - 408 | IPR001878-1 |
| domain | Zinc finger, CCHC-type | 413 - 429 | IPR001878-2 |
| active_site | Aspartic peptidase, active site | 510 - 521 | IPR001969 |
| domain | Peptidase A2A, retrovirus, catalytic | 508 - 577 | IPR001995 |
| domain | Ribonuclease H domain | 1021 - 1144 | IPR002156 |
| domain | Integrase, N-terminal zinc-binding domain | 1150 - 1191 | IPR003308 |
| domain | Reverse transcriptase connection | 905 - 1006 | IPR010659 |
| domain | Reverse transcriptase thumb | 829 - 890 | IPR010661 |
| domain | Retropepsins | 494 - 585 | IPR018061 |
| domain | Retropepsin-like catalytic domain | 499 - 579 | IPR034170 |
| domain | Retroviral nucleocapsid Gag protein p24, C-terminal domain | 277 - 349 | IPR045345 |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| galactose metabolic process | The chemical reactions and pathways involving galactose, the aldohexose galacto-hexose. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose. |
| regulation of DNA-templated transcription | Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTTITDIAKA | AGVSIATVSR | ILNYDTTLAV | TPETRQRVLK | TAEKLAYKPR | RRKRVSPQTT |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VALIQWRSEQ | EELNDLYYLQ | IQYAIEARAA | SAGYHLQSLH | LEQLAAETTQ | NVQGVIALGK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| YDAGEVATIK | ALAQPVVFVD | QNMLAFDCDS | VTSDYAGPIE | QIIHHFQSVG | INDIGFLGGV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| ETSRSGREQF | QDVRTAAFDR | VMHAENLMQP | AFRFIGAFTP | DSGYELMKQA | ITKLGDTLPH |
| 250 | 260 | 270 | 280 | 290 | 300 |
| GFIVANDTMA | VGALRALNEA | KIEVPQRVSV | ISFNDVAVAK | FTTPPLSTVH | AATDQMGQTA |
| 310 | 320 | 330 | |||
| VELLQARIKD | PKRIPRQVNF | KSELIMRASS | L |