O84789

PR
Gene name
rnpA
Protein name
Ribonuclease P protein component
Names
RNase P protein, RNaseP protein, Protein C5
Species
Chlamydia trachomatis (strain D/UW-3/Cx)
KEGG Pathway
ctr:CT_784
EC number
3.1.26.5: Endoribonucleases producing 5'-phosphomonoesters
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

73-120 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O84789

Entry ID Method Resolution Chain Position Source
AF-O84789-F1 Predicted AlphaFoldDB

No variants for O84789

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O84789

No associated diseases with O84789

1 regional properties for O84789

Type Name Position InterPro Accession
conserved_site Ribonuclease P, conserved site 56 - 70 IPR020539

Functions

Description
EC Number 3.1.26.5 Endoribonucleases producing 5'-phosphomonoesters
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
ribonuclease P complex A ribonucleoprotein complex that catalyzes cleavage of the leader sequence of precursor tRNAs (pre-tRNAs), generating the mature 5' end of tRNAs.

3 GO annotations of molecular function

Name Definition
3'-tRNA processing endoribonuclease activity Catalysis of the endonucleolytic cleavage of RNA, removing extra 3' nucleotides from tRNA precursor, generating 3' termini of tRNAs. A 3'-hydroxy group is left at the tRNA terminus and a 5'-phosphoryl group is left at the trailer molecule.
ribonuclease P activity Catalysis of the endonucleolytic cleavage of RNA, removing 5' extra nucleotides from tRNA precursor.
tRNA binding Binding to a transfer RNA.

2 GO annotations of biological process

Name Definition
tRNA 3'-trailer cleavage, endonucleolytic Endonucleolytic cleavage of the 3'-end of the pre-tRNA as part of the process of generating the mature 3'-end of the tRNA.
tRNA 5'-leader removal Generation of the mature 5'-end of the tRNA, usually via an endonucleolytic cleavage by RNase P.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSRLTLPKNA RLLKRKQFVY VQRNGRCCRA DQVTLRVVPS RHSNTRKVGI TVSKKFGKAH
70 80 90 100 110
QRNRFKRIVR EAFRHVRPNL PGCQVVISPR GNSQPDFLKL SEELLQRIPE ALPLASSSRC