O81263
Gene name |
TK (Os03g0113100, LOC_Os03g02200, OSJNBa0090O10.3) |
Protein name |
Thymidine kinase |
Names |
|
Species |
Oryza sativa subsp japonica (Rice) |
KEGG Pathway |
|
EC number |
2.7.1.21: Phosphotransferases with an alcohol group as acceptor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O81263
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O81263-F1 | Predicted | AlphaFoldDB |
No variants for O81263
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O81263 | |||||
No associated diseases with O81263
1 regional properties for O81263
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Thymidine kinase, conserved site | 232 - 245 | IPR020633 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.7.1.21 | Phosphotransferases with an alcohol group as acceptor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| metal ion binding | Binding to a metal ion. |
| thymidine kinase activity | Catalysis of the reaction: ATP + thymidine = ADP + thymidine 5'-phosphate. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| DNA biosynthetic process | The biosynthetic process resulting in the formation of DNA. |
| phosphorylation | The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide. |
| thymidine metabolic process | The chemical reactions and pathways involving thymidine, deoxyribosylthymine thymine 2-deoxyriboside, a deoxynucleoside very widely distributed but occurring almost entirely as phosphoric esters in deoxynucleotides and deoxyribonucleic acid, DNA. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MRSLLAASTF | LRSGASPLLR | PLSRPLPSRL | NLSRFGPVRP | VSAAAAAADK | SRGGGGSAME |
| 70 | 80 | 90 | 100 | 110 | 120 |
| AQPSYPGEIH | VIVGPMFAGK | TTALLRRVQV | EAGTGSRNVA | LIKSDKDNRY | GLDSVVTHDG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TKMPCWALPE | LSSFQDKLGT | EAYDKVDVIG | IDEAQFFDDL | HDFCCKAADR | DGKIVVVAGL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DGDYKRNKFG | SVLDIIPLAD | SVTKLTARCE | LCGRRAFFTL | RKTRETKTEL | IGGADVYMPV |
| 250 | 260 | 270 | |||
| CRQHYLDGQI | VIEATRIVLD | LEKSKVIHAF | K |