O80885
Gene name |
ARASP |
Protein name |
Membrane metalloprotease ARASP, chloroplastic |
Names |
|
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT2G32480 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O80885
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O80885-F1 | Predicted | AlphaFoldDB |
31 variants for O80885
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH01939241 | 6 | S>P | No | 1000Genomes | |
| tmp_2_13789980_G_C | 15 | P>A | No | 1000Genomes | |
| ENSVATH01939240 | 22 | N>S | No | 1000Genomes | |
| tmp_2_13789925_T_G | 33 | K>T | No | 1000Genomes | |
| tmp_2_13789920_G_A | 35 | H>Y | No | 1000Genomes | |
| tmp_2_13789905_G_A | 40 | H>Y | No | 1000Genomes | |
| ENSVATH05644086 | 42 | F>L | No | 1000Genomes | |
| ENSVATH14578450 | 42 | F>S | No | 1000Genomes | |
| tmp_2_13789896_G_T | 43 | P>T | No | 1000Genomes | |
| tmp_2_13789868_C_T | 52 | S>N | No | 1000Genomes | |
| ENSVATH01939237 | 63 | R>S | No | 1000Genomes | |
| tmp_2_13789770_A_C | 85 | F>V | No | 1000Genomes | |
| tmp_2_13789697_G_A | 109 | A>V | No | 1000Genomes | |
| ENSVATH05644084 | 121 | A>G | No | 1000Genomes | |
| ENSVATH14578448 | 131 | F>V | No | 1000Genomes | |
| tmp_2_13789505_G_A | 173 | T>I | No | 1000Genomes | |
| ENSVATH01939235 | 176 | R>K | No | 1000Genomes | |
| ENSVATH14578446 | 199 | V>M | No | 1000Genomes | |
| ENSVATH01939232 | 221 | F>V | No | 1000Genomes | |
| ENSVATH05644083 | 221 | F>Y | No | 1000Genomes | |
| ENSVATH05644082 | 234 | V>I | No | 1000Genomes | |
| ENSVATH05644080 | 275 | E>G | No | 1000Genomes | |
| ENSVATH14578444 | 275 | E>K | No | 1000Genomes | |
| tmp_2_13789191_C_T | 278 | D>N | No | 1000Genomes | |
| ENSVATH05644079 | 290 | T>M | No | 1000Genomes | |
| tmp_2_13789092_T_C | 311 | I>V | No | 1000Genomes | |
| tmp_2_13789082_G_C | 314 | T>R | No | 1000Genomes | |
| tmp_2_13789043_G_T | 327 | S>Y | No | 1000Genomes | |
| ENSVATH13506690 | 355 | A>V | No | 1000Genomes | |
| tmp_2_13788920_A_C | 368 | L>R | No | 1000Genomes | |
| ENSVATH05644078 | 402 | A>T | No | 1000Genomes |
No associated diseases with O80885
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| chloroplast | A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. |
| chloroplast inner membrane | The inner, i.e. lumen-facing, lipid bilayer of the chloroplast envelope; also faces the chloroplast stroma. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| metal ion binding | Binding to a metal ion. |
| metalloendopeptidase activity | Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| chloroplast organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the chloroplast. |
| proteolysis | The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MLLNISSSPI | SHRNPHFLSN | FNNPISYFPR | RSKTHLSKSH | FFPKFTPLSN | QSLKNRVLFG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| NKRYPDGERF | DFRSRAISGI | DLGSFESVLE | AIAVLTTIIV | VHESGHFLAA | SLQGIHVSKF |
| 130 | 140 | 150 | 160 | 170 | 180 |
| AIGFGPILAK | FDYNNVEYSL | RAFPLGGFVG | FPDNDPDSEI | PIDDENLLKN | RPTLDRSIVV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SAGIIANVIF | AYAIIFVQVL | SVGLPVQEAF | PGVLVPEVKT | FSAASRDGLL | SGDVILAVDG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| TELSKTGPDA | VSKIVDIVKR | NPKSNVVFRI | ERGGEDFDIR | VTPDKNFDGT | GKIGVQLSPN |
| 310 | 320 | 330 | 340 | 350 | 360 |
| VRITKVRPRN | IPETFRFVGR | EFMGLSSNVL | DGLKQTFFNF | SQTASKVAGP | VAIIAVGAEV |
| 370 | 380 | 390 | 400 | 410 | 420 |
| ARSNIDGLYQ | FAALLNINLA | VINLLPLPAL | DGGTLALILL | EAVRGGKKLP | VEVEQGIMSS |
| 430 | 440 | ||||
| GIMLVIFLGL | FLIVKDTLSL | DFIKEML |