O80562

PR
Gene name
HOL2 (At2g43920, F6E13.5)
Protein name
Probable thiol methyltransferase 1
Names
Protein HARMLESS TO OZONE LAYER 2, AtHOL2
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT2G43920
EC number
2.1.1.9: Methyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-53 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O80562

Entry ID Method Resolution Chain Position Source
AF-O80562-F1 Predicted AlphaFoldDB

15 variants for O80562

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_2_18191233_G_C 6 Q>E No 1000Genomes
ENSVATH05713249 8 S>L No 1000Genomes
ENSVATH13631976 21 E>K No 1000Genomes
ENSVATH14613253 41 E>K No 1000Genomes
tmp_2_18190324_G_A 83 A>V No 1000Genomes
ENSVATH00273763 102 N>K No 1000Genomes
ENSVATH05713214 109 G>V No 1000Genomes
tmp_2_18190072_T_A 130 N>Y No 1000Genomes
ENSVATH01985513 135 L>F No 1000Genomes
tmp_2_18189951_G_C 144 A>G No 1000Genomes
tmp_2_18189952_C_T 144 A>T No 1000Genomes
tmp_2_18189934_T_A 150 R>* No 1000Genomes
ENSVATH13631921 179 G>D No 1000Genomes
ENSVATH05713204 186 A>S No 1000Genomes
tmp_2_18189341_G_A 221 A>V No 1000Genomes

No associated diseases with O80562

No regional properties for O80562

Type Name Position InterPro Accession
No domain, repeats, and functional sites for O80562

Functions

Description
EC Number 2.1.1.9 Methyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

1 GO annotations of molecular function

Name Definition
thiol S-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + a thiol = S-adenosyl-L-homocysteine + a thioether.

1 GO annotations of biological process

Name Definition
methylation The process in which a methyl group is covalently attached to a molecule.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAEEQQNSSY SIGGNILPTP EEAATFQPQV VAEGGWDKCW EDGVTPWDQG RATPLILHLL
70 80 90 100 110 120
DSSALPLGRT LVPGCGGGHD VVAMASPERF VVGLDISDKA LNKANETYGS SPKAEYFSFV
130 140 150 160 170 180
KEDVFTWRPN ELFDLIFDYV FFCAIEPEMR PAWGKSMHEL LKPDGELITL MYPMTDHEGG
190 200 210 220
APYKVALSSY EDVLVPVGFK AVSVEENPDS IPTRKGKEKL ARWKKIN