O80467
Gene name |
SDT |
Protein name |
Spermidine sinapoyl-CoA acyltransferase |
Names |
AtSDT, Spermidine disinapoyl transferase |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT2G23510 |
EC number |
2.3.1.248: Transferring groups other than amino-acyl groups |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
2 structures for O80467
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 6LPW | X-ray | 240 A | A/B | 1-451 | PDB |
| AF-O80467-F1 | Predicted | AlphaFoldDB |
61 variants for O80467
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH13353126 | 2 | P>R | No | 1000Genomes | |
| tmp_2_10013511_G_A | 8 | S>L | No | 1000Genomes | |
| ENSVATH05567621 | 12 | M>V | No | 1000Genomes | |
| ENSVATH00243649 | 16 | M>L | No | 1000Genomes | |
| ENSVATH05567620 | 18 | T>S | No | 1000Genomes | |
| ENSVATH05567619 | 23 | P>S | No | 1000Genomes | |
| tmp_2_10013408_G_C | 42 | Y>* | No | 1000Genomes | |
| ENSVATH13353125 | 61 | D>Y | No | 1000Genomes | |
| tmp_2_10013323_C_T | 71 | E>K | No | 1000Genomes | |
| tmp_2_10013311_C_A | 75 | D>Y | No | 1000Genomes | |
| ENSVATH05567618 | 85 | G>W | No | 1000Genomes | |
| ENSVATH05567617 | 86 | S>T | No | 1000Genomes | |
| ENSVATH14538292 | 89 | R>P | No | 1000Genomes | |
| ENSVATH13353123 | 91 | E>K | No | 1000Genomes | |
| tmp_2_10013235_C_T | 100 | C>Y | No | 1000Genomes | |
| tmp_2_10013183_C_A | 117 | E>D | No | 1000Genomes | |
| ENSVATH14538291 | 123 | N>D | No | 1000Genomes | |
| tmp_2_10013135_C_G | 133 | L>F | No | 1000Genomes | |
| tmp_2_10013132_A_T | 134 | N>K | No | 1000Genomes | |
| tmp_2_10013122_C_A | 138 | V>L | No | 1000Genomes | |
| tmp_2_10013112_A_C | 141 | V>G | No | 1000Genomes | |
| ENSVATH14538290 | 143 | I>N | No | 1000Genomes | |
| ENSVATH13353120 | 144 | D>Y | No | 1000Genomes | |
| ENSVATH13353098 | 156 | F>V | No | 1000Genomes | |
| tmp_2_10012489_C_G | 164 | G>R | No | 1000Genomes | |
| tmp_2_10012437_A_C | 181 | M>R | No | 1000Genomes | |
| tmp_2_10012363_C_A | 206 | V>L | No | 1000Genomes | |
| ENSVATH05567601 | 209 | P>A | No | 1000Genomes | |
| ENSVATH05567601 | 209 | P>T | No | 1000Genomes | |
| tmp_2_10012288_C_T | 231 | D>N | No | 1000Genomes | |
| ENSVATH00243644 | 232 | D>G | No | 1000Genomes | |
| ENSVATH05567597 | 236 | E>D | No | 1000Genomes | |
| ENSVATH01875509 | 239 | T>N | No | 1000Genomes | |
| tmp_2_10012136_C_T | 246 | R>K | No | 1000Genomes | |
| ENSVATH13353074 | 256 | Y>C | No | 1000Genomes | |
| tmp_2_10012088_G_A | 262 | T>I | No | 1000Genomes | |
| tmp_2_10012071_C_A | 268 | V>F | No | 1000Genomes | |
| tmp_2_10012070_A_C | 268 | V>G | No | 1000Genomes | |
| tmp_2_10012068_T_C | 269 | I>V | No | 1000Genomes | |
| tmp_2_10011975_C_A | 300 | V>F | No | 1000Genomes | |
| ENSVATH05567594 | 305 | L>F | No | 1000Genomes | |
| ENSVATH09376583 | 311 | G>S | No | 1000Genomes | |
| ENSVATH13353073 | 319 | V>A | No | 1000Genomes | |
| ENSVATH00243642 | 321 | L>V | No | 1000Genomes | |
| tmp_2_10011897_C_A | 326 | V>L | No | 1000Genomes | |
| ENSVATH13353072 | 327 | E>D | No | 1000Genomes | |
| tmp_2_10011876_C_T | 333 | D>N | No | 1000Genomes | |
| ENSVATH01875501 | 339 | K>E | No | 1000Genomes | |
| tmp_2_10011846_T_C | 343 | R>G | No | 1000Genomes | |
| ENSVATH05567593 | 343 | R>T | No | 1000Genomes | |
| ENSVATH14538278 | 350 | Y>F | No | 1000Genomes | |
| ENSVATH14538279 | 350 | Y>H | No | 1000Genomes | |
| ENSVATH00243640 | 406 | S>L | No | 1000Genomes | |
| ENSVATH13353071 | 416 | M>I | No | 1000Genomes | |
| ENSVATH00243639 | 420 | R>K | No | 1000Genomes | |
| ENSVATH05567592 | 425 | M>V | No | 1000Genomes | |
| tmp_2_10011579_C_G | 432 | V>L | No | 1000Genomes | |
| ENSVATH00243638 | 437 | R>G | No | 1000Genomes | |
| ENSVATH13353069 | 443 | F>L | No | 1000Genomes | |
| tmp_2_10011543_T_G | 444 | K>Q | No | 1000Genomes | |
| ENSVATH01875500 | 451 | E>K | No | 1000Genomes |
No associated diseases with O80467
No regional properties for O80467
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for O80467 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 2.3.1.248 | Transferring groups other than amino-acyl groups |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| N-acyltransferase activity | Catalysis of the transfer of an acyl group to a nitrogen atom on the acceptor molecule. |
| sinapoyl spermidine:sinapoyl CoA N-acyltransferase activity | Catalysis of the transfer of a sinapoyl group to a nitrogen atom on a sinapoyl spermidine molecule resulting in the formation of a disinapoyl spermidine derivative. |
| spermidine:sinapoyl CoA N-acyltransferase activity | Catalysis of the transfer of a sinapoyl group to a nitrogen atom on the spermidine molecule. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| polyamine biosynthetic process | The chemical reactions and pathways resulting in the formation of polyamines, any organic compound containing two or more amino groups. |
| spermidine metabolic process | The chemical reactions and pathways involving spermidine, N-(3-aminopropyl)-1,4-diaminobutane. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MPIHIGSSIP | LMVEKMLTEM | VKPSKHIPQQ | TLNLSTLDND | PYNEVIYKAC | YVFKAKNVAD |
| 70 | 80 | 90 | 100 | 110 | 120 |
| DDNRPEALLR | EALSDLLGYY | YPLSGSLKRQ | ESDRKLQLSC | GGDGGGVPFT | VATANVELSS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LKNLENIDSD | TALNFLPVLH | VDIDGYRPFA | LQVTKFECGG | FILGMAMSHA | MCDGYGEGHI |
| 190 | 200 | 210 | 220 | 230 | 240 |
| MCALTDLAGG | KKKPMVTPIW | ERERLVGKPE | DDQPPFVPGD | DTAASPYLPT | DDWVTEKITI |
| 250 | 260 | 270 | 280 | 290 | 300 |
| RADSIRRLKE | ATLKEYDFSN | ETITTFEVIG | AYLWKSRVKA | LNLDRDGVTV | LGLSVGIRNV |
| 310 | 320 | 330 | 340 | 350 | 360 |
| VDPPLPDGYY | GNAYIDMYVP | LTAREVEEFT | ISDIVKLIKE | AKRNAHDKDY | LQEELANTEK |
| 370 | 380 | 390 | 400 | 410 | 420 |
| IIKMNLTIKG | KKDGLFCLTD | WRNIGIFGSM | DFGWDEPVNI | VPVVPSETAR | TVNMFMRPSR |
| 430 | 440 | 450 | |||
| LESDMVGGVQ | IVVTLPRIAM | VKFKEEMEAL | E |