O75427
PR
Gene name |
LRCH4 (LRN, LRRN1, LRRN4) |
Protein name |
Leucine-rich repeat and calponin homology domain-containing protein 4 |
Names |
Leucine-rich repeat neuronal protein 4, Leucine-rich neuronal protein |
Species |
Homo sapiens (Human) |
KEGG Pathway |
hsa:4034 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O75427
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O75427-F1 | Predicted | AlphaFoldDB |
594 variants for O75427
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
|
rs201008650 CA163283092 |
2 | A>G | No |
ClinGen gnomAD |
|
|
CA368549055 rs1162742401 |
3 | A>G | No |
ClinGen gnomAD |
|
|
CA368549052 rs1162742401 |
3 | A>V | No |
ClinGen gnomAD |
|
|
rs1473162611 CA368549045 |
4 | A>P | No |
ClinGen gnomAD |
|
|
rs1457183045 CA368549024 |
5 | V>A | No |
ClinGen TOPMed gnomAD |
|
|
CA368549029 CA368549026 rs1176674621 |
5 | V>L | No |
ClinGen gnomAD |
|
|
rs1319571981 CA368549008 |
6 | A>E | No |
ClinGen gnomAD |
|
|
rs1319571981 CA368549004 |
6 | A>G | No |
ClinGen gnomAD |
|
|
rs1200254788 CA368549018 |
6 | A>T | No |
ClinGen gnomAD |
|
|
rs776401187 CA4384826 |
7 | A>V | No |
ClinGen ExAC gnomAD |
|
|
CA4384825 rs768841691 |
9 | L>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4384824 rs761102006 |
11 | A>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA368548906 rs1444730682 |
12 | G>R | No |
ClinGen gnomAD |
|
|
rs965954364 CA368548890 |
13 | G>C | No |
ClinGen TOPMed gnomAD |
|
|
rs965954364 CA163283057 |
13 | G>S | No |
ClinGen TOPMed gnomAD |
|
|
rs772586363 CA4384822 |
13 | G>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1416011438 CA368548865 |
15 | E>K | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs866659553 CA163283037 |
16 | A>V | No |
ClinGen gnomAD |
|
|
rs1446914410 CA368548839 |
17 | A>T | No |
ClinGen TOPMed |
|
|
rs1380778082 CA368548823 |
18 | A>T | No |
ClinGen gnomAD |
|
|
rs1180286426 CA368548808 |
18 | A>V | No |
ClinGen gnomAD |
|
|
CA368548806 rs1487382406 |
19 | T>A | No |
ClinGen gnomAD |
|
|
CA4384820 rs771102730 |
22 | V>L | No |
ClinGen ExAC gnomAD |
|
|
CA4384819 rs771102730 |
22 | V>M | No |
ClinGen ExAC gnomAD |
|
|
CA368548730 rs1271053402 |
23 | P>S | No |
ClinGen TOPMed |
|
|
CA368548686 rs377121985 |
25 | S>C | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA4384816 rs377121985 |
25 | S>F | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA368548683 rs377121985 |
25 | S>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA368548670 rs1365896901 |
26 | P>L | No |
ClinGen gnomAD |
|
|
rs1225889952 CA368548672 |
26 | P>S | No |
ClinGen gnomAD |
|
|
CA368548653 rs1437492075 |
27 | G>D | No |
ClinGen gnomAD |
|
|
CA368548629 rs1367632228 |
29 | P>T | No |
ClinGen gnomAD |
|
|
CA368548602 rs1296439470 |
30 | G>E | No |
ClinGen gnomAD |
|
|
rs1364573134 CA368548609 |
30 | G>W | No |
ClinGen TOPMed |
|
|
rs373246308 CA4384814 |
32 | R>C | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1431278475 CA368548550 |
33 | S>N | No |
ClinGen gnomAD |
|
|
CA4384813 rs369514792 |
33 | S>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA368548534 rs1424172376 |
34 | A>T | No |
ClinGen gnomAD |
|
|
rs1191516384 CA368548526 |
34 | A>V | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs764824645 CA4384811 |
36 | R>G | No |
ClinGen ExAC gnomAD |
|
|
CA368548501 rs1260506225 |
36 | R>Q | No |
ClinGen gnomAD |
|
|
rs764824645 CA4384812 |
36 | R>W | No |
ClinGen ExAC gnomAD |
|
|
CA368548493 rs1215344215 |
37 | A>P | No |
ClinGen TOPMed gnomAD |
|
|
CA368548496 rs1215344215 |
37 | A>T | No |
ClinGen TOPMed gnomAD |
|
|
rs1304895039 CA368548481 |
37 | A>V | No |
ClinGen TOPMed |
|
|
rs753362292 CA4384809 |
39 | E>G | No |
ClinGen ExAC gnomAD |
|
|
CA4384810 rs149959065 |
39 | E>K | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs753362292 CA368548448 |
39 | E>V | No |
ClinGen ExAC gnomAD |
|
|
CA163283005 rs909150 |
40 | E>D | No |
ClinGen Ensembl |
|
|
CA368548406 rs1403834616 COSM1446585 |
41 | A>V | large_intestine Variant assessed as Somatic; impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated NCI-TCGA TOPMed |
|
CA4384808 rs763834783 |
43 | A>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA368548377 rs1220122713 |
43 | A>V | No |
ClinGen gnomAD |
|
|
rs139180317 CA4384807 |
44 | T>I | No |
ClinGen ESP ExAC gnomAD |
|
|
rs139180317 CA368548364 |
44 | T>N | No |
ClinGen ESP ExAC gnomAD |
|
|
rs139180317 CA368548361 |
44 | T>S | No |
ClinGen ESP ExAC gnomAD |
|
|
rs377766601 CA4384805 |
45 | G>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA368548323 rs1341186997 |
46 | T>N | No |
ClinGen gnomAD |
|
|
rs1337137343 CA368548333 |
46 | T>P | No |
ClinGen TOPMed |
|
|
rs1026903358 CA163282962 |
48 | N>I | No |
ClinGen TOPMed |
|
|
CA368548262 rs1223796614 |
51 | N>S | No |
ClinGen TOPMed |
|
|
CA4384800 rs777810122 |
52 | R>Q | No |
ClinGen ExAC gnomAD |
|
|
CA4384801 rs749418398 |
52 | R>W | No |
ClinGen ExAC gnomAD |
|
|
CA4384798 rs748420896 |
53 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4384797 rs779990445 |
53 | R>L | No |
ClinGen ExAC gnomAD |
|
|
rs748420896 CA368548223 |
53 | R>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA368548200 rs1179938670 |
54 | L>W | No |
ClinGen TOPMed |
|
|
rs1482572327 CA368548179 |
55 | K>N | No |
ClinGen TOPMed gnomAD |
|
|
rs758324776 CA368548163 |
56 | H>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1326090720 CA368548144 |
58 | P>T | No |
ClinGen gnomAD |
|
|
CA368548132 rs756678338 TCGA novel |
59 | R>G | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen ExAC TOPMed gnomAD NCI-TCGA |
|
CA4384792 rs753407580 |
59 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs756678338 CA4384793 |
59 | R>W | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1378428957 CA368548101 |
62 | A>T | No |
ClinGen gnomAD |
|
|
rs975752731 CA163282885 |
63 | R>C | No |
ClinGen gnomAD |
|
|
rs767815300 CA4384788 |
63 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs767815300 CA163282874 |
63 | R>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs374940211 CA4384786 |
65 | Y>C | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1162099143 CA368548032 |
67 | L>M | No |
ClinGen gnomAD |
|
|
CA368547974 rs1462969296 |
71 | T>A | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs200251319 CA4384783 |
71 | T>I | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA4384782 rs371707535 |
72 | Q>L | No |
ClinGen ESP ExAC gnomAD |
|
|
CA368547932 COSM743727 rs1318893369 |
74 | D>N | lung [Cosmic] | No |
ClinGen cosmic curated gnomAD |
|
CA4384734 rs370331867 |
77 | R>Q | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs773153494 CA4384735 |
77 | R>W | No |
ClinGen ExAC gnomAD |
|
|
rs1584410103 CA368546528 |
78 | N>T | No |
ClinGen Ensembl |
|
|
CA368546504 rs1156743671 |
79 | R>Q | No |
ClinGen TOPMed gnomAD |
|
|
rs1367434984 CA368546511 |
79 | R>W | No |
ClinGen gnomAD |
|
|
CA4384733 rs557058360 |
81 | P>L | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA4384730 rs377324041 |
82 | E>K | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA4384731 rs377324041 |
82 | E>Q | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA368546445 rs1476845029 |
83 | V>M | No |
ClinGen TOPMed gnomAD |
|
|
COSM1312472 CA4384726 rs779466665 |
85 | E>K | Variant assessed as Somatic; 0.0 impact. urinary_tract [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
rs148352509 CA4384725 |
86 | A>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs764215412 CA4384723 |
87 | A>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA368546339 rs1584410047 |
88 | C>G | No |
ClinGen Ensembl |
|
|
rs1282868316 CA368546285 |
90 | L>P | No |
ClinGen gnomAD |
|
| TCGA novel | 94 | E>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs767657708 CA4384720 |
94 | E>K | No |
ClinGen ExAC gnomAD |
|
|
rs1452994805 CA368546206 |
95 | G>D | No |
ClinGen gnomAD |
|
|
CA163280108 rs759852946 |
97 | S>I | No |
ClinGen ExAC gnomAD |
|
|
CA4384719 rs759852946 |
97 | S>N | No |
ClinGen ExAC gnomAD |
|
|
CA4384718 rs772852644 |
98 | L>P | No |
ClinGen ExAC gnomAD |
|
|
rs1412544758 CA368546031 |
102 | C>W | No |
ClinGen gnomAD |
|
|
CA368545989 rs769644731 |
104 | R>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs769644731 CA4384717 COSM743728 |
104 | R>T | lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
rs761724792 CA4384716 |
105 | C>Y | No |
ClinGen ExAC |
|
|
CA368545920 rs1584410005 |
107 | N>T | No |
ClinGen Ensembl |
|
|
rs746531511 CA4384712 |
111 | G>E | No |
ClinGen ExAC gnomAD |
|
|
CA368545726 rs1218452450 |
115 | A>D | No |
ClinGen gnomAD |
|
|
rs1562809156 CA368545735 |
115 | A>T | No |
ClinGen Ensembl |
|
|
CA368545689 rs1584409962 |
117 | T>P | No |
ClinGen Ensembl |
|
|
CA368545655 rs1310783828 |
118 | Y>F | No |
ClinGen gnomAD |
|
|
rs1310783828 CA368545654 |
118 | Y>S | No |
ClinGen gnomAD |
|
|
CA368545588 rs1314970598 |
120 | N>S | No |
ClinGen TOPMed |
|
|
CA4384709 rs745570035 |
121 | L>F | No |
ClinGen ExAC gnomAD |
|
|
CA368545548 rs1296031955 |
122 | S>R | No |
ClinGen TOPMed |
|
|
CA4384692 rs771675049 |
122 | S>R | No |
ClinGen ExAC gnomAD |
|
|
CA4384691 rs745489976 |
123 | R>* | No |
ClinGen ExAC gnomAD |
|
|
CA4384690 rs774155638 |
123 | R>Q | No |
ClinGen ExAC gnomAD |
|
|
rs1469307623 CA368545425 |
124 | N>S | No |
ClinGen TOPMed |
|
|
CA368545373 rs1297227962 |
127 | S>L | No |
ClinGen gnomAD |
|
|
CA163279906 rs1026477805 |
131 | P>L | No |
ClinGen TOPMed |
|
|
CA4384688 rs749694509 |
134 | C>F | No |
ClinGen ExAC gnomAD |
|
|
rs1311024920 CA368545046 |
135 | Q>H | No |
ClinGen gnomAD |
|
|
CA4384687 rs778335117 |
137 | P>S | No |
ClinGen ExAC gnomAD |
|
|
CA368544998 rs1160059095 |
141 | L>F | No |
ClinGen TOPMed |
|
|
CA4384684 rs375555119 |
143 | V>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA368544930 rs1158239136 |
145 | N>K | No |
ClinGen TOPMed |
|
|
CA4384682 rs751713297 |
150 | A>G | No |
ClinGen ExAC gnomAD |
|
|
rs766617482 CA4384681 |
152 | P>L | No |
ClinGen ExAC gnomAD |
|
|
CA4384680 rs756995516 |
153 | P>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs376458621 CA4384678 |
154 | D>G | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA4384677 rs763987791 |
156 | G>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1584409643 CA368544791 |
157 | T>P | No |
ClinGen Ensembl |
|
|
CA368544784 rs1391505302 |
157 | T>S | No |
ClinGen TOPMed |
|
|
CA4384676 rs760520509 |
162 | R>* | No |
ClinGen ExAC gnomAD |
|
|
rs1181461905 CA368544699 COSM1082873 |
162 | R>Q | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA TOPMed gnomAD |
|
rs775551944 CA4384675 |
163 | Q>R | No |
ClinGen ExAC gnomAD |
|
|
rs907271094 CA163279857 |
164 | L>F | No |
ClinGen TOPMed |
|
| rs762682145 | 165 | D>= | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA368544463 rs1469493732 |
166 | V>A | No |
ClinGen gnomAD |
|
|
CA4384651 rs376833789 |
166 | V>M | No |
ClinGen 1000Genomes ESP ExAC gnomAD |
|
|
rs769985518 CA4384650 |
167 | S>N | No |
ClinGen ExAC gnomAD |
|
|
CA368544387 rs1474460131 |
168 | S>R | No |
ClinGen gnomAD |
|
|
CA163279759 rs149222783 |
169 | N>K | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1010541239 CA163279767 |
169 | N>S | No |
ClinGen Ensembl |
|
|
rs1193775558 CA368544284 |
170 | E>* | No |
ClinGen gnomAD |
|
|
rs776954148 CA4384648 |
170 | E>D | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1193775558 CA368544286 |
170 | E>Q | No |
ClinGen gnomAD |
|
|
CA4384646 rs747551194 |
172 | Q>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs541658430 CA163279745 |
175 | P>L | No |
ClinGen 1000Genomes |
|
|
rs577346930 CA4384642 |
176 | S>L | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA368544073 rs1336015034 |
178 | L>R | No |
ClinGen gnomAD |
|
|
CA368544055 rs1428587182 |
179 | C>W | No |
ClinGen TOPMed |
|
|
rs559237662 CA163279744 |
181 | L>P | No |
ClinGen 1000Genomes |
|
|
rs144925164 CA368544008 |
182 | S>C | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs144925164 CA4384640 |
182 | S>F | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA368543955 rs780893020 |
185 | R>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4384639 rs780893020 |
185 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA368543960 rs1367899449 |
185 | R>W | No |
ClinGen TOPMed gnomAD |
|
|
CA4384637 rs751604651 |
186 | D>N | No |
ClinGen ExAC gnomAD |
|
|
CA368543950 rs751604651 |
186 | D>Y | No |
ClinGen ExAC gnomAD |
|
|
rs138523541 CA4384636 |
188 | N>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs750002351 CA4384634 |
189 | V>I | No |
ClinGen ExAC gnomAD |
|
|
CA4384633 rs764962596 |
190 | R>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA368543823 rs1476360883 |
190 | R>W | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA4384632 rs761421119 |
193 | Q>K | No |
ClinGen ExAC gnomAD |
|
|
rs777022450 CA4384631 |
193 | Q>R | No |
ClinGen ExAC gnomAD |
|
|
CA4384630 rs769071548 |
195 | S>G | No |
ClinGen ExAC gnomAD |
|
|
CA4384629 rs369431110 |
195 | S>I | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs769071548 CA368543676 |
195 | S>R | No |
ClinGen ExAC gnomAD |
|
|
rs149828516 CA4384628 |
196 | T>M | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs1245763705 CA368543599 COSM1082872 |
199 | E>K | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA gnomAD |
|
CA368541548 rs1584406359 |
203 | D>A | No |
ClinGen Ensembl |
|
|
rs535627175 CA163277481 |
203 | D>Y | No |
ClinGen TOPMed gnomAD |
|
|
CA4384599 rs146938731 |
204 | L>F | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs183189535 CA163277479 |
205 | P>A | No |
ClinGen 1000Genomes |
|
|
CA4384598 rs368111306 |
205 | P>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA4384597 rs551961361 |
208 | R>C | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs539637465 CA4384595 |
208 | R>H | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs539637465 CA4384596 |
208 | R>L | No |
ClinGen 1000Genomes ExAC gnomAD |
|
| TCGA novel | 211 | F>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 212 | S>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA4384594 rs753461028 |
215 | R>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA368541270 rs1287025294 COSM1082871 |
215 | R>H | Variant assessed as Somatic; 0.0 impact. endometrium stomach [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA TOPMed gnomAD |
|
CA4384592 RCV000881736 rs52833865 |
216 | V>I | No |
ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
CA4384591 rs753031999 |
218 | R>* | No |
ClinGen ExAC gnomAD |
|
|
CA368541216 rs753031999 |
218 | R>G | No |
ClinGen ExAC gnomAD |
|
|
CA368541211 rs767940631 |
218 | R>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4384590 rs767940631 |
218 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 220 | P>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA368541062 rs1176615772 |
225 | R>C | No |
ClinGen TOPMed gnomAD |
|
|
CA4384588 rs372575327 |
225 | R>H | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA368541068 rs1176615772 |
225 | R>S | No |
ClinGen TOPMed gnomAD |
|
|
CA368541034 rs1427911148 |
227 | R>G | No |
ClinGen gnomAD |
|
|
rs1485797471 CA368540965 |
230 | Q>P | No |
ClinGen gnomAD |
|
|
rs762977065 CA4384586 |
231 | V>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs368249205 CA4384583 |
236 | S>G | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA368540840 rs1262735113 |
236 | S>N | No |
ClinGen gnomAD |
|
|
CA4384582 rs775420067 |
236 | S>R | No |
ClinGen ExAC gnomAD |
|
|
rs375534637 CA4384581 |
237 | N>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1402336680 CA368540814 |
238 | P>T | No |
ClinGen TOPMed |
|
|
CA4384578 rs770432048 |
240 | Q>E | No |
ClinGen ExAC gnomAD |
|
|
rs748777489 CA368540780 |
241 | S>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA368540779 rs1450183630 |
241 | S>N | No |
ClinGen gnomAD |
|
|
rs748777489 CA4384577 |
241 | S>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1404979940 CA368540766 |
243 | P>S | No |
ClinGen gnomAD |
|
|
rs777307216 CA4384576 |
244 | A>P | No |
ClinGen ExAC |
|
|
rs1436992966 CA368540758 |
244 | A>V | No |
ClinGen TOPMed gnomAD |
|
|
CA368540644 rs1305822772 |
247 | C>* | No |
ClinGen gnomAD |
|
|
CA4384542 rs764242893 |
254 | I>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA163277340 rs1045292467 |
255 | F>S | No |
ClinGen TOPMed gnomAD |
|
|
rs760999862 CA4384541 |
259 | S>F | No |
ClinGen ExAC gnomAD |
|
|
CA4384540 rs563982959 |
260 | T>I | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs147809975 CA4384539 |
262 | A>T | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA368540277 rs1473010846 |
262 | A>V | No |
ClinGen gnomAD |
|
|
CA4384536 rs769255269 |
263 | G>E | No |
ClinGen ExAC gnomAD |
|
|
CA4384537 rs377254850 |
263 | G>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA4384535 rs747681853 |
265 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs776255264 CA4384534 |
265 | R>H | No |
ClinGen ExAC gnomAD |
|
|
CA368540229 rs776255264 |
265 | R>L | No |
ClinGen ExAC gnomAD |
|
|
CA163277326 rs200374154 |
267 | S>L | No |
ClinGen TOPMed gnomAD |
|
|
CA4384531 rs780267624 |
270 | G>R | No |
ClinGen ExAC gnomAD |
|
|
rs746305510 CA4384529 |
271 | D>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4384530 rs758847147 |
271 | D>N | No |
ClinGen ExAC gnomAD |
|
|
CA368540117 rs779591158 |
272 | L>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs757359484 CA4384527 |
272 | L>R | No |
ClinGen ExAC gnomAD |
|
|
CA4384526 rs753836677 |
274 | P>L | No |
ClinGen ExAC gnomAD |
|
|
CA368540065 rs1383283071 |
275 | S>C | No |
ClinGen gnomAD |
|
|
rs563611987 CA4384524 |
276 | R>Q | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA4384525 rs764303783 |
276 | R>W | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs752980657 CA4384523 |
277 | P>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA368540045 rs752980657 |
277 | P>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs766099566 CA368540019 |
278 | P>L | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs766099566 CA4384522 |
278 | P>Q | No |
ClinGen ExAC gnomAD |
|
|
rs773086125 CA4384520 |
281 | S>R | No |
ClinGen ExAC gnomAD |
|
|
rs765137965 CA4384519 |
282 | P>L | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA368539768 rs1360017754 |
283 | C>* | No |
ClinGen TOPMed |
|
|
CA368539730 rs765082338 |
285 | A>G | No |
ClinGen ExAC gnomAD |
|
|
CA4384500 rs149693391 |
285 | A>P | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA4384499 rs765082338 |
285 | A>V | No |
ClinGen ExAC gnomAD |
|
|
rs1229654658 CA368539691 |
287 | D>V | No |
ClinGen gnomAD |
|
|
rs1313310339 CA368539633 |
290 | P>A | No |
ClinGen gnomAD |
|
|
CA4384497 rs753827515 |
290 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA163277260 rs1025421229 |
292 | H>R | No |
ClinGen TOPMed gnomAD |
|
|
CA4384495 rs573328250 |
292 | H>Y | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA368539556 rs771824805 |
293 | R>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4384493 rs771824805 |
293 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4384494 rs187288824 COSM1082870 |
293 | R>W | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA163277249 rs531826474 |
295 | D>G | No |
ClinGen TOPMed gnomAD |
|
|
rs774845337 CA4384491 |
295 | D>N | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 296 | G>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA4384490 rs771438499 |
296 | G>S | No |
ClinGen ExAC gnomAD |
|
|
rs1012491686 CA163277247 |
296 | G>V | No |
ClinGen TOPMed gnomAD |
|
|
rs749694842 CA4384488 |
298 | L>M | No |
ClinGen ExAC gnomAD |
|
|
CA368539400 rs1179108228 |
299 | D>E | No |
ClinGen TOPMed gnomAD |
|
|
CA368539384 rs1251857396 |
300 | S>L | No |
ClinGen gnomAD |
|
|
CA163277244 rs182581434 |
301 | G>C | No |
ClinGen 1000Genomes |
|
|
rs142600009 CA4384485 |
305 | V>I | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA163277239 rs1026827777 |
306 | D>V | No |
ClinGen Ensembl |
|
|
CA4384483 rs539671273 |
308 | G>D | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs1440171980 CA368539237 |
309 | S>R | No |
ClinGen gnomAD |
|
|
CA368539200 rs1345603203 |
311 | R>K | No |
ClinGen gnomAD |
|
|
rs755191108 CA4384482 |
312 | W>G | No |
ClinGen ExAC gnomAD |
|
|
CA163277232 rs76980489 |
313 | S>A | No |
ClinGen Ensembl |
|
|
rs1308669747 CA368539121 |
314 | G>E | No |
ClinGen gnomAD |
|
| TCGA novel | 316 | E>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA368537580 rs1400423923 |
317 | S>* | No |
ClinGen TOPMed |
|
|
CA4384460 rs777468490 |
318 | T>A | No |
ClinGen ExAC gnomAD |
|
|
rs756072567 CA4384459 |
318 | T>I | No |
ClinGen ExAC gnomAD |
|
|
CA368537547 rs1478618416 |
319 | D>N | No |
ClinGen gnomAD |
|
| TCGA novel | 319 | D>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA368537517 rs1248820136 |
320 | E>K | No |
ClinGen gnomAD |
|
|
rs1466812553 CA368537423 |
322 | S>L | No |
ClinGen TOPMed |
|
|
rs767069957 CA4384457 |
327 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4384458 rs752697341 |
327 | R>W | No |
ClinGen ExAC gnomAD |
|
|
CA368537290 rs1562806219 |
328 | I>F | No |
ClinGen Ensembl |
|
|
CA368537234 rs1268975152 |
329 | S>L | No |
ClinGen gnomAD |
|
| TCGA novel | 331 | L>Q | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
COSM3698050 CA4384455 rs191101243 |
333 | R>Q | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs377002060 CA4384456 |
333 | R>W | Variant assessed as Somatic; 4.624e-05 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA163277142 rs919739720 |
335 | P>A | No |
ClinGen TOPMed gnomAD |
|
|
CA163277149 rs919739720 |
335 | P>S | No |
ClinGen TOPMed gnomAD |
|
|
rs762557450 CA4384454 |
336 | R>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4384453 rs762557450 |
336 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1318708986 CA368537132 |
336 | R>W | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
CA163277140 rs1011889505 |
337 | G>E | No |
ClinGen TOPMed |
|
|
CA4384451 rs765580734 |
337 | G>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4384449 rs77942585 |
338 | P>S | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs386716129 CA163277138 |
338 | P>S | No |
ClinGen Ensembl |
|
|
rs144231638 CA163277134 |
341 | R>C | No |
ClinGen ESP ExAC gnomAD |
|
|
COSM1195561 rs368611886 CA4384447 |
341 | R>H | lung [Cosmic] | No |
ClinGen cosmic curated ESP ExAC gnomAD |
|
rs368611886 CA4384446 |
341 | R>P | No |
ClinGen ESP ExAC gnomAD |
|
|
rs144231638 CA4384448 |
341 | R>S | No |
ClinGen ESP ExAC gnomAD |
|
|
rs954887975 CA163277129 |
342 | K>E | No |
ClinGen Ensembl |
|
| TCGA novel | 342 | K>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA4384443 rs376109684 |
343 | E>K | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA4384444 rs376109684 |
343 | E>Q | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1248985887 CA368536992 |
345 | G>S | No |
ClinGen gnomAD |
|
|
rs1056466447 CA163277106 |
347 | A>V | No |
ClinGen gnomAD |
|
|
rs1220596344 CA368536898 |
348 | D>H | No |
ClinGen TOPMed |
|
|
rs369164222 CA4384426 |
349 | G>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs769664168 CA368536864 |
350 | D>A | No |
ClinGen ExAC gnomAD |
|
|
rs769664168 CA4384425 |
350 | D>G | No |
ClinGen ExAC gnomAD |
|
|
rs781177002 CA4384423 |
351 | P>L | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs747934379 CA4384424 |
351 | P>S | No |
ClinGen ExAC gnomAD |
|
|
rs1276523526 CA368536827 |
353 | Q>K | No |
ClinGen gnomAD |
|
|
CA4384422 rs139516267 |
354 | I>T | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA4384421 rs200805374 |
356 | F>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA4384420 rs779561244 |
357 | I>V | No |
ClinGen ExAC gnomAD |
|
|
rs919710348 CA163277064 |
358 | D>G | No |
ClinGen gnomAD |
|
|
CA4384418 rs750048626 |
358 | D>N | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed |
|
rs778448822 CA4384417 |
359 | S>N | No |
ClinGen ExAC gnomAD |
|
|
CA368536729 rs1478501834 |
359 | S>R | No |
ClinGen TOPMed |
|
| TCGA novel | 360 | H>P | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA4384416 rs756948432 |
360 | H>Y | No |
ClinGen ExAC |
|
|
rs1306803852 CA368536688 |
361 | V>F | No |
ClinGen TOPMed gnomAD |
|
|
CA368536693 rs1306803852 |
361 | V>I | No |
ClinGen TOPMed gnomAD |
|
|
CA368536663 rs1456685413 |
363 | G>A | No |
ClinGen gnomAD |
|
|
CA4384412 rs753151554 |
363 | G>R | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA368536665 rs753151554 |
363 | G>W | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1433321950 CA368536644 |
365 | D>V | No |
ClinGen TOPMed |
|
|
rs767595647 CA4384411 |
368 | R>G | No |
ClinGen ExAC |
|
|
rs759557651 CA4384410 |
368 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs942529635 CA163277021 |
370 | T>I | No |
ClinGen TOPMed gnomAD |
|
|
rs1181470806 CA368536559 |
371 | V>A | No |
ClinGen TOPMed gnomAD |
|
|
CA4384406 rs763337889 |
372 | E>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs770439567 CA4384380 |
374 | Q>L | No |
ClinGen ExAC gnomAD |
|
|
CA368536424 rs1390936558 |
375 | R>* | No |
ClinGen gnomAD |
|
|
CA4384379 rs368166440 |
375 | R>Q | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA368536406 rs1355597327 |
376 | P>S | No |
ClinGen TOPMed |
|
|
rs755840897 CA4384377 |
377 | P>R | No |
ClinGen ExAC gnomAD |
|
|
rs1378130594 CA368536385 |
377 | P>S | No |
ClinGen gnomAD |
|
|
CA163276900 rs1011724577 COSM1662616 |
378 | E>K | kidney Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated NCI-TCGA gnomAD |
|
CA368536207 rs1253476213 |
384 | G>E | No |
ClinGen gnomAD |
|
|
CA368536190 rs1199372438 |
385 | D>G | No |
ClinGen gnomAD |
|
|
CA368536134 rs1237087373 |
387 | E>* | No |
ClinGen gnomAD |
|
|
rs752129086 CA4384373 |
388 | R>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA163276831 rs2686810 |
391 | S>N | No |
ClinGen Ensembl |
|
|
CA368536007 rs1367605632 |
392 | S>N | No |
ClinGen gnomAD |
|
|
CA368535881 rs140761835 |
394 | R>L | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA4384344 rs140761835 |
394 | R>Q | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs748921886 CA4384345 |
394 | R>W | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs762945239 CA4384343 |
395 | E>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4384342 rs762945239 |
395 | E>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4384340 COSM3698049 rs769364186 |
397 | P>L | large_intestine Variant assessed as Somatic; 0.0001621 impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
CA4384341 rs772699164 |
397 | P>S | No |
ClinGen ExAC gnomAD |
|
|
CA368535759 rs1322585764 |
398 | A>V | No |
ClinGen gnomAD |
|
|
CA368535758 rs1405657132 |
399 | G>R | No |
ClinGen gnomAD |
|
|
CA368535727 rs1562805727 |
400 | E>V | No |
ClinGen Ensembl |
|
|
CA368535694 rs1183574932 |
401 | E>D | No |
ClinGen gnomAD |
|
|
rs1456229949 CA368535707 |
401 | E>K | No |
ClinGen gnomAD |
|
|
CA368535699 rs1411997229 |
401 | E>V | No |
ClinGen gnomAD |
|
|
rs768851548 CA4384337 |
402 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA368535678 rs1471403594 |
402 | R>W | No |
ClinGen TOPMed gnomAD |
|
|
rs747353792 CA4384336 |
403 | R>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4384335 rs530626700 |
403 | R>Q | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA368535662 rs747353792 |
403 | R>W | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs373208078 CA4384334 |
404 | R>C | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA4384332 rs369763673 |
404 | R>H | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs369763673 CA4384333 |
404 | R>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA4384330 rs150962857 |
405 | P>L | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs757360489 CA4384331 |
405 | P>S | No |
ClinGen ExAC |
|
|
rs751351053 CA4384327 |
407 | T>A | No |
ClinGen ExAC gnomAD |
|
|
CA368535552 rs1365394446 |
407 | T>I | No |
ClinGen gnomAD |
|
|
rs762823669 CA4384325 |
410 | L>P | No |
ClinGen ExAC gnomAD |
|
|
rs1483787507 CA576713331 |
411 | W>* | No |
ClinGen TOPMed |
|
|
CA368535472 rs1562805671 |
411 | W>* | No |
ClinGen Ensembl |
|
|
CA368535441 rs1318156419 |
412 | Q>* | No |
ClinGen gnomAD |
|
|
CA163276648 rs764615072 |
414 | R>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4384323 rs764615072 |
414 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs201757672 COSM1256678 CA4384324 |
414 | R>W | oesophagus [Cosmic] | No |
ClinGen cosmic curated ESP ExAC TOPMed gnomAD |
|
CA4384321 rs776051139 |
416 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4384322 rs761412341 |
416 | R>W | No |
ClinGen ExAC gnomAD |
|
|
rs760466759 CA4384319 |
417 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs768321694 CA4384320 |
417 | R>W | No |
ClinGen ExAC gnomAD |
|
|
CA4384317 rs772577478 |
418 | Q>* | No |
ClinGen ExAC gnomAD |
|
|
rs1273024188 CA368535375 |
419 | Q>* | No |
ClinGen gnomAD |
|
|
CA368535307 rs1464569051 |
422 | S>N | No |
ClinGen gnomAD |
|
|
CA4384312 rs779503954 |
422 | S>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA368535285 rs1310411318 |
423 | G>E | No |
ClinGen gnomAD |
|
|
CA4384310 rs770865237 |
423 | G>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4384308 rs777783218 |
424 | A>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs749358816 CA4384309 |
424 | A>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA368535272 rs777783218 |
424 | A>V | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs1433918466 CA368535257 |
425 | W>* | No |
ClinGen gnomAD |
|
|
rs752933880 CA368535264 |
425 | W>* | No |
ClinGen ExAC gnomAD |
|
|
rs752933880 CA4384306 |
425 | W>S | No |
ClinGen ExAC gnomAD |
|
|
CA4384305 rs779761204 |
426 | G>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA368535250 rs1213559527 |
426 | G>R | No |
ClinGen TOPMed |
|
|
CA4384303 rs765196008 |
427 | A>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4384302 rs765196008 |
427 | A>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs765196008 CA4384304 |
427 | A>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4384300 rs753379286 |
428 | P>L | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 429 | R>E | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA4384298 rs760345848 |
429 | R>K | No |
ClinGen ExAC gnomAD |
|
|
rs1218005840 CA368535185 |
431 | D>N | No |
ClinGen TOPMed |
|
|
CA4384278 rs752347730 |
433 | L>F | No |
ClinGen ExAC gnomAD |
|
|
rs1204234621 CA368534983 CA368534984 |
437 | G>R | No |
ClinGen gnomAD |
|
| TCGA novel | 438 | L>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA4384276 rs759179156 |
439 | R>S | No |
ClinGen ExAC gnomAD |
|
|
CA368534924 rs1252077932 |
441 | V>I | No |
ClinGen TOPMed |
|
|
CA368534897 rs1320733921 |
443 | G>R | No |
ClinGen TOPMed gnomAD |
|
|
rs867464703 CA163276548 |
445 | A>D | No |
ClinGen Ensembl |
|
|
rs542063588 CA4384272 |
446 | A>T | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA368534836 rs1399585587 |
446 | A>V | No |
ClinGen TOPMed |
|
|
rs1374517050 CA368534828 COSM1082869 |
447 | A>T | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA TOPMed gnomAD |
|
rs1300205385 CA368534820 |
447 | A>V | No |
ClinGen gnomAD |
|
|
rs914538038 CA163276538 |
448 | V>A | No |
ClinGen gnomAD |
|
|
rs769820187 CA4384270 |
448 | V>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1409782510 CA368534770 |
451 | Q>E | No |
ClinGen gnomAD |
|
|
rs574920929 CA4384268 |
451 | Q>H | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs959033026 CA163276533 |
453 | M>K | No |
ClinGen TOPMed gnomAD |
|
|
rs959033026 CA163276535 |
453 | M>T | No |
ClinGen TOPMed gnomAD |
|
|
rs1281746440 CA368534735 |
453 | M>V | No |
ClinGen TOPMed |
|
|
CA163276527 rs747251090 |
454 | H>Q | No |
ClinGen ExAC gnomAD |
|
|
CA368534709 rs1313461826 |
454 | H>R | No |
ClinGen TOPMed |
|
|
rs768856972 CA4384267 |
454 | H>Y | No |
ClinGen ExAC TOPMed gnomAD |
|
| rs199833602 | 455 | N>= | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs776675060 CA4384249 |
456 | G>C | No |
ClinGen ExAC gnomAD |
|
|
CA4384248 rs571081699 |
457 | S>L | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA368533817 rs571081699 |
457 | S>W | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs199982219 CA163276479 |
458 | P>S | No |
ClinGen 1000Genomes TOPMed gnomAD |
|
|
CA163276476 rs971763894 |
459 | K>T | No |
ClinGen TOPMed |
|
|
CA4384245 rs369601562 |
461 | S>I | No |
ClinGen ESP ExAC gnomAD |
|
|
CA4384246 rs369601562 |
461 | S>N | No |
ClinGen ESP ExAC gnomAD |
|
|
rs1024315912 CA163276473 |
461 | S>R | No |
ClinGen TOPMed |
|
|
CA368533715 rs369601562 |
461 | S>T | No |
ClinGen ESP ExAC gnomAD |
|
|
CA4384243 rs777749815 |
462 | A>G | No |
ClinGen ExAC gnomAD |
|
|
rs749068908 CA4384244 |
462 | A>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA368533683 rs749068908 |
462 | A>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA368533655 rs1562805360 |
463 | S>F | No |
ClinGen Ensembl |
|
|
rs1304536664 CA368533591 |
465 | A>V | No |
ClinGen TOPMed gnomAD |
|
|
rs769842767 CA4384242 |
466 | G>R | No |
ClinGen ExAC gnomAD |
|
|
CA4384241 rs748110103 |
466 | G>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs771979965 CA163276469 |
467 | A>G | No |
ClinGen Ensembl |
|
|
rs780784068 CA4384240 |
468 | A>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1416820724 CA368533502 |
468 | A>T | No |
ClinGen gnomAD |
|
|
CA368533497 rs780784068 |
468 | A>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4384238 rs375173199 |
469 | A>E | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA4384239 rs375173199 COSM199493 |
469 | A>V | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA368533421 rs1395473923 |
472 | G>R | No |
ClinGen gnomAD |
|
|
CA368533405 rs1175269908 |
473 | A>G | No |
ClinGen TOPMed gnomAD |
|
|
CA368533401 rs1175269908 |
473 | A>V | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs750778260 CA368533389 |
474 | P>H | No |
ClinGen ExAC gnomAD |
|
|
rs750778260 CA4384235 |
474 | P>L | No |
ClinGen ExAC gnomAD |
|
|
CA163276460 rs370950472 |
475 | A>T | No |
ClinGen ESP gnomAD |
|
|
CA368533362 rs1448246272 |
475 | A>V | No |
ClinGen gnomAD |
|
|
CA368533334 rs1253408021 |
476 | P>L | No |
ClinGen TOPMed gnomAD |
|
|
CA4384230 rs569815074 |
477 | A>T | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA4384229 rs764193242 |
478 | P>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA368533269 rs760691766 |
479 | A>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4384228 rs760691766 |
479 | A>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1269856915 CA368533251 |
479 | A>V | No |
ClinGen TOPMed gnomAD |
|
|
CA4384226 rs775688687 |
481 | Q>R | No |
ClinGen ExAC gnomAD |
|
|
rs772152865 CA4384225 |
482 | E>D | No |
ClinGen ExAC gnomAD |
|
|
CA368533150 rs1314533379 COSM50564 |
483 | P>L | large_intestine [Cosmic] | No |
ClinGen cosmic curated gnomAD |
| TCGA novel | 485 | P>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs773084693 CA4384223 |
486 | I>V | No |
ClinGen ExAC gnomAD |
|
|
rs1476149728 CA368533007 |
488 | G>E | No |
ClinGen TOPMed gnomAD |
|
|
rs1476149728 CA368533002 |
488 | G>V | No |
ClinGen TOPMed gnomAD |
|
|
rs529932552 CA4384221 |
489 | P>R | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs767650564 CA4384204 |
490 | A>V | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs1407858859 CA368532779 |
491 | T>I | No |
ClinGen gnomAD |
|
|
CA368532746 rs1159556813 |
492 | A>V | No |
ClinGen gnomAD |
|
|
CA4384201 rs765077735 |
493 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs76551586 CA4384202 |
493 | P>S | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs1054828804 CA163276409 |
494 | A>V | No |
ClinGen TOPMed |
|
|
CA368532658 rs1193243407 |
495 | P>L | No |
ClinGen gnomAD |
|
|
rs1255026072 CA368532644 |
496 | R>L | No |
ClinGen TOPMed gnomAD |
|
|
CA368532649 rs1255026072 |
496 | R>Q | No |
ClinGen TOPMed gnomAD |
|
|
CA4384200 rs761681238 |
496 | R>W | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs952165220 CA163276404 |
497 | P>Q | No |
ClinGen TOPMed gnomAD |
|
|
rs370077970 CA163276407 |
497 | P>S | No |
ClinGen ESP TOPMed |
|
|
rs1310416965 CA368532617 |
498 | L>F | No |
ClinGen TOPMed gnomAD |
|
|
rs745582986 CA163276399 |
499 | G>D | No |
ClinGen Ensembl |
|
|
CA163276401 rs937359122 |
499 | G>S | No |
ClinGen TOPMed gnomAD |
|
|
CA368532551 rs776533200 |
500 | S>C | No |
ClinGen ExAC gnomAD |
|
|
CA4384199 rs776533200 |
500 | S>F | No |
ClinGen ExAC gnomAD |
|
|
rs768477550 CA4384198 |
501 | I>S | No |
ClinGen ExAC gnomAD |
|
|
CA163276395 rs972522356 |
501 | I>V | No |
ClinGen TOPMed gnomAD |
|
|
CA4384196 rs774801531 |
503 | R>K | No |
ClinGen ExAC gnomAD |
|
|
rs1439965145 CA368532448 |
505 | N>D | No |
ClinGen TOPMed |
|
|
CA368532365 rs1318007149 |
508 | L>F | No |
ClinGen gnomAD |
|
|
CA4384194 rs745480050 |
510 | R>C | No |
ClinGen ExAC gnomAD |
|
|
rs150672994 CA4384193 |
510 | R>H | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA163276390 rs867804306 |
518 | G>C | No |
ClinGen Ensembl |
|
|
CA368531945 rs1367454288 |
518 | G>D | No |
ClinGen TOPMed |
|
|
CA368531921 rs200696855 |
519 | P>H | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA4384170 rs200696855 |
519 | P>L | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA4384171 rs541574425 |
519 | P>S | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA4384169 rs756533087 |
520 | S>F | No |
ClinGen ExAC gnomAD |
|
|
rs748557159 CA4384168 |
521 | S>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs755583792 CA368531831 |
523 | D>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1176406844 CA368531814 |
523 | D>E | No |
ClinGen gnomAD |
|
|
rs781759433 CA4384167 |
523 | D>N | No |
ClinGen ExAC gnomAD |
|
|
CA4384166 rs755583792 |
523 | D>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1234233622 CA368531794 |
524 | S>F | No |
ClinGen gnomAD |
|
|
rs1480777196 CA368531805 |
524 | S>T | No |
ClinGen gnomAD |
|
|
rs1218859743 CA368531768 |
526 | L>V | No |
ClinGen gnomAD |
|
|
rs141934676 CA368531738 |
527 | R>I | No |
ClinGen ESP ExAC gnomAD |
|
|
CA4384165 rs141934676 |
527 | R>K | No |
ClinGen ESP ExAC gnomAD |
|
| TCGA novel | 528 | P>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA163276248 rs376994322 |
529 | R>G | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs35432811 CA163276244 |
529 | R>P | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs35432811 CA4384161 |
529 | R>Q | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA4384162 rs376994322 |
529 | R>W | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs759535697 CA4384157 |
530 | R>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs759535697 CA4384158 |
530 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs752481510 CA4384160 |
530 | R>W | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs577507745 CA163276241 |
531 | Y>H | No |
ClinGen 1000Genomes |
|
|
rs1321922904 CA368531611 |
532 | P>A | No |
ClinGen TOPMed |
|
|
CA368531592 rs1300149499 |
532 | P>L | No |
ClinGen gnomAD |
|
|
CA368531567 rs1393846112 |
533 | Q>H | No |
ClinGen gnomAD |
|
| TCGA novel | 533 | Q>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA163276236 rs893654209 |
534 | V>F | No |
ClinGen Ensembl |
|
|
CA368531480 rs1349668117 |
536 | D>G | No |
ClinGen TOPMed |
|
|
rs770433035 CA368531406 |
538 | K>R | No |
ClinGen ExAC gnomAD |
|
|
rs770433035 CA4384155 |
538 | K>T | No |
ClinGen ExAC gnomAD |
|
|
CA4384154 rs372379699 |
539 | D>N | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1348680156 CA368531331 |
541 | M>V | No |
ClinGen TOPMed |
|
|
CA4384153 rs141807671 |
545 | R>C | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA4384152 rs370008127 |
545 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA368531250 rs370008127 |
545 | R>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs138668883 CA4384151 |
546 | Q>E | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA368531081 rs1375798224 |
548 | L>F | No |
ClinGen TOPMed gnomAD |
|
|
CA368531083 rs1375798224 |
548 | L>V | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 549 | E>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA4384121 rs751406236 |
551 | R>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs548519774 CA4384122 |
551 | R>W | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA4384118 rs376944603 |
554 | R>Q | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA4384119 rs758337211 |
554 | R>W | No |
ClinGen ExAC gnomAD |
|
|
rs1186364680 CA368529845 |
555 | P>A | No |
ClinGen gnomAD |
|
|
rs761495195 CA4384116 |
556 | L>P | No |
ClinGen ExAC gnomAD |
|
|
CA368529796 rs1250869585 |
557 | P>L | No |
ClinGen gnomAD |
|
|
CA368529738 rs1342400508 |
559 | D>E | No |
ClinGen gnomAD |
|
|
rs911722950 CA163275649 |
561 | A>T | No |
ClinGen TOPMed gnomAD |
|
|
CA368529627 rs1222019356 |
562 | E>D | No |
ClinGen Ensembl |
|
|
CA368529641 rs1305391932 |
562 | E>G | No |
ClinGen TOPMed |
|
|
CA4384114 rs764501444 |
562 | E>K | Variant assessed as Somatic; 5.3e-05 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs1314471855 CA368529625 |
563 | A>T | No |
ClinGen TOPMed gnomAD |
|
|
CA368529533 rs1395274844 |
565 | A>P | No |
ClinGen TOPMed gnomAD |
|
|
rs1395274844 CA368529540 |
565 | A>T | No |
ClinGen TOPMed gnomAD |
|
|
rs1168037952 CA368529421 |
567 | G>E | No |
ClinGen gnomAD |
|
|
CA4384113 rs199995742 |
570 | L>M | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs772626877 CA4384111 |
571 | C>Y | No |
ClinGen ExAC gnomAD |
|
|
rs924224314 CA163275627 |
574 | A>D | No |
ClinGen gnomAD |
|
|
CA368529246 rs1190016273 |
574 | A>T | No |
ClinGen gnomAD |
|
|
rs924224314 CA368529230 |
574 | A>V | No |
ClinGen gnomAD |
|
|
rs774431576 CA4384109 |
575 | N>D | No |
ClinGen ExAC gnomAD |
|
|
CA4384110 rs774431576 |
575 | N>H | No |
ClinGen ExAC gnomAD |
|
|
rs749463016 CA4384107 |
576 | Q>H | No |
ClinGen ExAC gnomAD |
|
|
rs770920180 CA4384108 |
576 | Q>R | No |
ClinGen ExAC gnomAD |
|
|
rs953096811 CA163275623 |
577 | L>I | No |
ClinGen TOPMed |
|
|
rs897151194 CA368529151 |
578 | R>L | No |
ClinGen TOPMed gnomAD |
|
|
rs897151194 CA163275618 |
578 | R>Q | No |
ClinGen TOPMed gnomAD |
|
|
CA4384105 rs367912586 |
578 | R>W | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs746804965 CA4384104 |
579 | P>L | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs758301066 CA4384102 |
580 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs750336915 CA4384101 |
580 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA4384098 rs753444990 |
582 | V>M | No |
ClinGen ExAC gnomAD |
|
|
rs1419186655 CA368529082 |
584 | F>L | No |
ClinGen gnomAD |
|
| TCGA novel | 585 | I>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs763806094 CA4384097 |
586 | H>Y | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 588 | P>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1182821672 CA368528967 |
591 | A>T | No |
ClinGen gnomAD |
|
|
rs1246980161 CA368528945 |
592 | V>M | No |
ClinGen Ensembl |
|
|
rs777481880 CA4384079 |
593 | P>A | No |
ClinGen ExAC gnomAD |
|
|
rs777481880 CA368528811 |
593 | P>S | No |
ClinGen ExAC gnomAD |
|
|
CA163275562 rs891784767 |
595 | L>R | No |
ClinGen TOPMed gnomAD |
|
|
CA4384077 rs752295458 |
597 | A>V | No |
ClinGen ExAC gnomAD |
|
|
CA368528642 rs1366487913 |
600 | A>V | No |
ClinGen TOPMed |
|
|
rs767882536 CA368528637 |
601 | R>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1326321525 CA368528633 |
601 | R>Q | No |
ClinGen gnomAD |
|
|
rs767882536 CA4384076 |
601 | R>W | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs751995918 CA4384074 |
606 | S>G | No |
ClinGen ExAC gnomAD |
|
|
CA368528502 rs1173253233 |
606 | S>R | No |
ClinGen gnomAD |
|
|
CA4384073 rs766865065 |
607 | F>L | No |
ClinGen ExAC gnomAD |
|
|
rs1427426579 CA368528468 |
609 | E>K | No |
ClinGen gnomAD |
|
|
rs763507534 CA4384072 |
610 | A>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA368528429 rs1242656221 |
611 | C>F | No |
ClinGen TOPMed gnomAD |
|
|
CA368528439 rs1407946784 |
611 | C>R | No |
ClinGen TOPMed |
|
|
rs375508989 CA4384071 |
612 | R>* | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA4384070 rs769864680 |
612 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4384068 rs776736804 |
613 | K>E | No |
ClinGen ExAC gnomAD |
|
|
CA4384067 rs370210208 |
614 | M>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1584402988 CA368528343 |
616 | V>G | No |
ClinGen Ensembl |
|
|
CA4384065 rs778837614 |
618 | E>K | No |
ClinGen ExAC TOPMed |
|
|
rs3197597 VAR_051135 |
642 | V>M | No |
UniProt dbSNP |
|
| rs748668021 | 644 | R>W | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No | NCI-TCGA |
| rs757069747 | 647 | G>A | Variant assessed as Somatic; 4.982e-05 impact. [NCI-TCGA] | No | NCI-TCGA |
| rs763893611 | 649 | A>V | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No | NCI-TCGA |
| rs377536480 | 663 | V>I | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 669 | L>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
No associated diseases with O75427
8 regional properties for O75427
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| repeat | Leucine-rich repeat | 74 - 136 | IPR001611-1 |
| repeat | Leucine-rich repeat | 138 - 194 | IPR001611-2 |
| domain | Calponin homology domain | 534 - 647 | IPR001715 |
| repeat | Leucine-rich repeat, typical subtype | 90 - 112 | IPR003591-1 |
| repeat | Leucine-rich repeat, typical subtype | 113 - 136 | IPR003591-2 |
| repeat | Leucine-rich repeat, typical subtype | 158 - 180 | IPR003591-3 |
| repeat | Leucine-rich repeat, typical subtype | 181 - 204 | IPR003591-4 |
| repeat | Leucine-rich repeat, typical subtype | 226 - 249 | IPR003591-5 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| PML body | A class of nuclear body; they react against SP100 auto-antibodies (PML, promyelocytic leukemia); cells typically contain 10-30 PML bodies per nucleus; alterations in the localization of PML bodies occurs after viral infection. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| negative regulation of DNA-templated transcription | Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription. |
| nervous system development | The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAAAVAAPLA | AGGEEAAATT | SVPGSPGLPG | RRSAERALEE | AVATGTLNLS | NRRLKHFPRG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| AARSYDLSDI | TQADLSRNRF | PEVPEAACQL | VSLEGLSLYH | NCLRCLNPAL | GNLTALTYLN |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LSRNQLSLLP | PYICQLPLRV | LIVSNNKLGA | LPPDIGTLGS | LRQLDVSSNE | LQSLPSELCG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LSSLRDLNVR | RNQLSTLPEE | LGDLPLVRLD | FSCNRVSRIP | VSFCRLRHLQ | VILLDSNPLQ |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SPPAQVCLKG | KLHIFKYLST | EAGQRGSALG | DLAPSRPPSF | SPCPAEDLFP | GHRYDGGLDS |
| 310 | 320 | 330 | 340 | 350 | 360 |
| GFHSVDSGSK | RWSGNESTDE | FSELSFRISE | LAREPRGPRE | RKEDGSADGD | PVQIDFIDSH |
| 370 | 380 | 390 | 400 | 410 | 420 |
| VPGEDEERGT | VEEQRPPELS | PGAGDRERAP | SSRREEPAGE | ERRRPDTLQL | WQERERRQQQ |
| 430 | 440 | 450 | 460 | 470 | 480 |
| QSGAWGAPRK | DSLLKPGLRA | VVGGAAAVST | QAMHNGSPKS | SASQAGAAAG | QGAPAPAPAS |
| 490 | 500 | 510 | 520 | 530 | 540 |
| QEPLPIAGPA | TAPAPRPLGS | IQRPNSFLFR | SSSQSGSGPS | SPDSVLRPRR | YPQVPDEKDL |
| 550 | 560 | 570 | 580 | 590 | 600 |
| MTQLRQVLES | RLQRPLPEDL | AEALASGVIL | CQLANQLRPR | SVPFIHVPSP | AVPKLSALKA |
| 610 | 620 | 630 | 640 | 650 | 660 |
| RKNVESFLEA | CRKMGVPEAD | LCSPSDLLQG | TARGLRTALE | AVKRVGGKAL | PPLWPPSGLG |
| 670 | 680 | ||||
| GFVVFYVVLM | LLLYVTYTRL | LGS |