AiPD: Autoinhibited Protein Database

O75153

Gene name	CLUH (KIAA0664)
Protein name	Clustered mitochondria protein homolog
Names
Species	Homo sapiens (Human)
KEGG Pathway	hsa:23277
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

615-697 (Predicted disordered autoinhibitory region) PR

Target domain
Relief mechanism
Assay	cis-regPred

AID

615-697 (Predicted disordered autoinhibitory region)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Yeon JH et al. (2016) "Systems-wide Identification of cis-Regulatory Elements in Proteins", Cell Systems, 2, 89-100

Autoinhibited structure

Activated structure

1 structures for O75153

Entry ID	Method	Resolution	Chain	Position	Source
AF-O75153-F1	Predicted				AlphaFoldDB

1231 variants for O75153

Variant ID(s)	Position	Change	Description	Diseaes Association	Provenance
CA8283571 rs201361018 RCV000508604	1183	D>H	Hirschsprung disease, susceptibility to, 1 [ClinVar]	Yes	ClinGen ClinVar ESP ExAC TOPMed dbSNP gnomAD
CA397656704 rs1345704800	2	L>I		No	ClinGen gnomAD
CA397656699 rs1476924166	2	L>R		No	ClinGen TOPMed
rs1304605953 CA397656686	4	N>I		No	ClinGen gnomAD
rs372372818 CA286948330	5	G>R		No	ClinGen ESP TOPMed gnomAD
rs1168061153 CA397656676	6	D>Y		No	ClinGen gnomAD
rs1041341826 CA286948326	8	P>L		No	ClinGen TOPMed gnomAD
CA397656657 rs1041341826	8	P>R		No	ClinGen TOPMed gnomAD
rs1421455673 CA397656645	10	S>N		No	ClinGen gnomAD
CA397656636 rs1169660149	11	L>V		No	ClinGen TOPMed gnomAD
TCGA novel	12	K>Q	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs761532142 CA8285054	15	A>V		No	ClinGen ExAC TOPMed gnomAD
CA286948323 rs953540168	16	A>S		No	ClinGen Ensembl
CA8285053 rs367881781	16	A>V		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs945829721 CA286948315	17	A>S		No	ClinGen TOPMed gnomAD
rs945829721 CA397656576	17	A>T		No	ClinGen TOPMed gnomAD
rs746244540 CA8285051	17	A>V		No	ClinGen ExAC TOPMed gnomAD
rs372091511 CA8285048	19	E>K		No	ClinGen ESP ExAC TOPMed gnomAD
rs777803170 CA8285047	20	P>T		No	ClinGen ExAC gnomAD
rs1015115102 CA286948261	24	N>S		No	ClinGen gnomAD
TCGA novel	26	L>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA397656508 CA8285045 rs781424734	27	D>E		No	ClinGen ExAC TOPMed gnomAD
rs754663425 CA8285043	28	E>D		No	ClinGen ExAC gnomAD
CA286948246 rs1051504426	28	E>K		No	ClinGen TOPMed gnomAD
CA286948218 rs934194853	30	G>D		No	ClinGen TOPMed gnomAD
rs766153587 CA8285041	30	G>S		No	ClinGen ExAC TOPMed gnomAD
CA8285040 rs758323365	31	P>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs758323365 CA397656488	31	P>Q		No	ClinGen ExAC TOPMed gnomAD
rs758323365 CA397656487	31	P>R		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	32	G>E	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA397656468 rs1182567903	34	E>G		No	ClinGen gnomAD
rs370308550 CA8285037	36	T>N		No	ClinGen ESP ExAC TOPMed gnomAD
rs764787924 CA8285038	36	T>S		No	ClinGen ExAC gnomAD
rs377462406 CA8285035	37	G>S		No	ClinGen ESP ExAC TOPMed gnomAD
rs1343817946 CA397656441	39	E>K		No	ClinGen gnomAD
rs983215116 CA286948114	40	V>A		No	ClinGen TOPMed
CA397656429 rs983215116	40	V>G		No	ClinGen TOPMed
CA397656424 rs1350059647	41	I>T		No	ClinGen TOPMed
rs1279806351 CA397656421	42	V>I		No	ClinGen gnomAD
CA397656407 rs1438360627	44	Q>E	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
CA8285034 rs760307515	44	Q>H		No	ClinGen ExAC gnomAD
CA8285033 rs774778650	46	T>A		No	ClinGen ExAC gnomAD
rs771243070 CA8285032	46	T>M		No	ClinGen ExAC TOPMed gnomAD
CA397656387 rs1408268016	47	G>C		No	ClinGen gnomAD
CA397656386 rs1331913267	47	G>D		No	ClinGen gnomAD
CA397656367 rs1401704585	50	V>L		No	ClinGen gnomAD
rs1159379382 CA397656354	52	I>V		No	ClinGen gnomAD
CA397656344 rs1567596671	53	L>H		No	ClinGen Ensembl
rs893485696 CA397656341	54	A>S		No	ClinGen TOPMed gnomAD
COSM2799744 COSM2799745 rs893485696 CA286948047	54	A>T	Variant assessed as Somatic; 0.0 impact. breast [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated NCI-TCGA TOPMed gnomAD
CA397656340 rs1445733349	54	A>V		No	ClinGen gnomAD
rs544102456 CA397656336	55	P>A		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA8285026 rs544102456	55	P>S		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA8285024 rs779874600	57	I>F		No	ClinGen ExAC gnomAD
rs201016965 CA397656321	57	I>M		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA397656325 rs779874600	57	I>V		No	ClinGen ExAC gnomAD
CA8285022 rs750344066	58	E>K		No	ClinGen ExAC gnomAD
CA397656313 rs1351144771	59	P>S		No	ClinGen gnomAD
CA397656312 rs1351144771	59	P>T		No	ClinGen gnomAD
TCGA novel	60	F>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	60	F>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1282388732 CA397656295	61	S>F		No	ClinGen gnomAD
CA8285021 rs557751325	61	S>P		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs768559063 CA286948041	63	Q>R		No	ClinGen Ensembl
CA397656093 rs1435882715	64	V>A		No	ClinGen gnomAD
CA397656095 rs1291840871	64	V>L		No	ClinGen gnomAD
CA8284982 rs371929718	65	S>Y		No	ClinGen ESP ExAC gnomAD
rs1423340901 CA397656081	66	P>L		No	ClinGen gnomAD
rs1207243016 CA397656084	66	P>S		No	ClinGen TOPMed
TCGA novel	67	Q>P	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1177334387	67	Q>R	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	NCI-TCGA
rs367955542 CA8284980	68	E>K		No	ClinGen ESP ExAC TOPMed gnomAD
rs752164477 CA8284979	69	M>I		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	72	E>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1597622027 CA397656007	76	V>G		No	ClinGen Ensembl
CA397655997 rs765536846	78	M>R		No	ClinGen ExAC gnomAD
rs765536846 CA8284975	78	M>T		No	ClinGen ExAC gnomAD
CA8284976 rs751259194	78	M>V		No	ClinGen ExAC TOPMed gnomAD
rs567580688 CA286946951	80	R>G		No	ClinGen gnomAD
CA8284974 rs762114359	80	R>Q		No	ClinGen ExAC TOPMed gnomAD
rs567580688 CA397655985	80	R>W		No	ClinGen gnomAD
CA8284973 rs754301042	83	T>M		No	ClinGen ExAC TOPMed gnomAD
CA397655947 rs1218655695	85	H>Q		No	ClinGen gnomAD
CA397655941 rs1377764355	86	R>H		No	ClinGen gnomAD
CA8284969 rs772321344	89	F>S		No	ClinGen ExAC
rs759812919 CA8284968	92	H>Y		No	ClinGen ExAC gnomAD
CA397655869 rs1419710806	97	V>A		No	ClinGen TOPMed gnomAD
CA397655873 rs1174918205	97	V>M		No	ClinGen TOPMed gnomAD
rs199946016 CA8284964	100	H>Y		No	ClinGen 1000Genomes ExAC gnomAD
CA8284962 rs748184428	102	S>L		No	ClinGen ExAC TOPMed gnomAD
rs754504703 CA8284960	103	E>Q		No	ClinGen ExAC gnomAD
CA8284959 rs746623392	105	R>C		No	ClinGen ExAC TOPMed gnomAD
rs550332953 CA397655792	105	R>H		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs550332953 CA8284958	105	R>L		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA8284957 rs757581358	106	S>G		No	ClinGen ExAC gnomAD
rs371781621 CA8284955	107	V>I		No	ClinGen ESP ExAC TOPMed gnomAD
rs1314104939 CA397655753	108	E>K		No	ClinGen gnomAD
rs753308512 CA8284953	108	E>V		No	ClinGen ExAC gnomAD
TCGA novel	113	G>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs774649116 COSM976805 COSM976806 CA8284950	117	R>H	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
rs1368918508 CA397655615	117	R>S		No	ClinGen gnomAD
rs1422046793 CA397655608	118	V>M		No	ClinGen gnomAD
rs368270746 CA8284936	122	P>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA8284933 rs370845530	124	T>M		No	ClinGen ESP ExAC TOPMed gnomAD
rs750678711 CA8284929	126	R>C		No	ClinGen ExAC gnomAD
rs1389876216 CA397655389	126	R>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA286945220 rs895497307	127	E>D		No	ClinGen TOPMed gnomAD
CA397655348 rs1466937789	129	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs764898710 CA8284928	129	R>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs764898710 CA286945212	129	R>L		No	ClinGen ExAC TOPMed gnomAD
CA8284926 rs776492697	132	V>M		No	ClinGen ExAC TOPMed gnomAD
CA397655273 rs1201024736	134	H>N		No	ClinGen gnomAD
rs760668084 CA8284924	134	H>R		No	ClinGen ExAC TOPMed gnomAD
rs771664686 CA8284922	137	D>H		No	ClinGen ExAC gnomAD
rs1597619909 CA397655193	139	L>P		No	ClinGen Ensembl
CA8284920 rs778662076	140	K>R		No	ClinGen ExAC gnomAD
CA397655131 rs1243958389	143	D>G		No	ClinGen TOPMed
CA397655138 rs1276282162	143	D>H		No	ClinGen gnomAD
CA8284916 rs755538744	146	D>G		No	ClinGen ExAC gnomAD
CA8284917 rs781728255	146	D>N	Variant assessed as Somatic; 4.65e-05 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs752153628 CA8284915	147	A>T		No	ClinGen ExAC gnomAD
rs1330394729 CA397655026	150	G>E		No	ClinGen gnomAD
CA397655034 rs1486212398	150	G>R		No	ClinGen TOPMed
CA397654994 rs1403102524	152	D>E		No	ClinGen gnomAD
rs758534660 CA8284913	152	D>N		No	ClinGen ExAC TOPMed gnomAD
CA8284912 rs750544852	154	N>H		No	ClinGen ExAC gnomAD
CA397654961 rs1464785892	154	N>K		No	ClinGen gnomAD
rs1394556359 CA397654944	156	L>S		No	ClinGen gnomAD
rs1423805796 CA397654895	161	V>A		No	ClinGen TOPMed
rs1423805796 CA397654894	161	V>G		No	ClinGen TOPMed
rs374296887 CA286945097	162	F>L		No	ClinGen ESP
rs1194496270 CA397654889	162	F>V		No	ClinGen TOPMed
CA8284909 rs532628319	164	D>N		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA8284906 rs775523268	165	G>D		No	ClinGen ExAC gnomAD
rs760580215 CA8284907	165	G>S		No	ClinGen ExAC TOPMed gnomAD
CA8284904 rs759094720	166	D>N		No	ClinGen ExAC TOPMed gnomAD
CA8284878 rs75023474	170	S>R		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA397654675 rs1487144055	171	G>E		No	ClinGen gnomAD
CA8284876 rs757349320	171	G>R		No	ClinGen ExAC gnomAD
CA8284874 rs777979457	172	K>N		No	ClinGen ExAC gnomAD
CA8284875 rs749474991	172	K>R		No	ClinGen ExAC gnomAD
CA8284872 rs76563327	173	R>P		No	ClinGen 1000Genomes ExAC gnomAD
rs76563327 CA8284871	173	R>Q		No	ClinGen 1000Genomes ExAC gnomAD
rs755849179 CA8284873	173	R>W		No	ClinGen ExAC TOPMed gnomAD
CA8284868 rs765939683	175	K>R		No	ClinGen ExAC gnomAD
rs1220688360 CA397654594	176	G>V		No	ClinGen gnomAD
rs1269649590 CA397654560 COSM3937293 COSM3937294	178	E>D	oesophagus [Cosmic]	No	ClinGen cosmic curated TOPMed gnomAD
rs1437305395 CA397654543	179	M>I		No	ClinGen gnomAD
rs762554283 CA8284867	180	D>G		No	ClinGen ExAC gnomAD
rs1461434602 CA397654510	181	P>L		No	ClinGen gnomAD
CA397654518 rs1438626769	181	P>S		No	ClinGen TOPMed
CA397654501 rs1292002653	182	I>N		No	ClinGen TOPMed
CA397654508 rs1401480341	182	I>V		No	ClinGen gnomAD
rs201221332 CA8284863	183	D>G		No	ClinGen 1000Genomes ExAC
rs761439519 CA8284864	183	D>N		No	ClinGen ExAC TOPMed gnomAD
rs1418379894 CA397654476	184	C>Y		No	ClinGen gnomAD
rs1290649297 CA397654470	185	T>A		No	ClinGen TOPMed
rs1260253825 CA397654463	186	P>T		No	ClinGen gnomAD
CA397654454 rs1478728234	187	P>L		No	ClinGen gnomAD
rs1228353500 CA397654452	188	E>K		No	ClinGen TOPMed
rs1219561673 CA397654424	192	P>A		No	ClinGen TOPMed gnomAD
rs1219561673 CA397654423	192	P>S		No	ClinGen TOPMed gnomAD
rs1196578727 CA397654401	195	R>Q		No	ClinGen TOPMed gnomAD
rs368488282 CA8284860	195	R>W		No	ClinGen ESP ExAC TOPMed gnomAD
CA397654400 rs1305930757	196	E>K		No	ClinGen gnomAD
rs770933896 CA8284859	197	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs1272595354 CA397654391	197	R>W		No	ClinGen gnomAD
rs1040801274 CA286943214	198	P>Q		No	ClinGen TOPMed
rs1369834342 CA397654388	198	P>S		No	ClinGen gnomAD
CA397654383 rs749387226	199	L>M		No	ClinGen ExAC gnomAD
rs749387226 CA8284858	199	L>V		No	ClinGen ExAC gnomAD
CA397654366 rs1333734628	201	P>L		No	ClinGen gnomAD
CA397654369 rs1378362177	201	P>S		No	ClinGen gnomAD
CA8284855 rs748359247	203	Q>*		No	ClinGen ExAC gnomAD
rs781020122 CA8284854	205	Q>E		No	ClinGen ExAC gnomAD
rs751445378 CA8284852	207	R>C		No	ClinGen ExAC TOPMed gnomAD
rs780152388 CA8284851	207	R>H		No	ClinGen ExAC TOPMed gnomAD
rs1349347656 CA397654319	209	W>R		No	ClinGen TOPMed
CA8284850 rs758466305	210	K>E		No	ClinGen ExAC gnomAD
CA397654308 rs1480187473	210	K>R		No	ClinGen gnomAD
rs1286678912 CA397654287	211	P>L		No	ClinGen gnomAD
rs1279112482 CA397654266	214	C>F		No	ClinGen TOPMed
rs1203968711 CA397654270	214	C>R		No	ClinGen TOPMed
rs773732576 CA8284822	216	K>Q		No	ClinGen ExAC
CA8284821 rs769880098	217	V>I		No	ClinGen ExAC gnomAD
CA397654244 rs1166604144	218	L>F		No	ClinGen gnomAD
rs1007286257 CA286942955	219	T>I		No	ClinGen Ensembl
rs1415881952 CA397654230	220	M>I		No	ClinGen gnomAD
rs761809741 CA8284820	220	M>T		No	ClinGen ExAC TOPMed gnomAD
rs1597618737 CA397654222	221	S>N		No	ClinGen Ensembl
rs1478311187 CA397654219	222	G>R	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA397654192 rs1236770652	225	P>L		No	ClinGen TOPMed
rs1263904990 CA397654196	225	P>S		No	ClinGen gnomAD
CA8284817 rs747274261	227	P>L		No	ClinGen ExAC TOPMed gnomAD
rs1224149204 CA397654179	228	G>R		No	ClinGen gnomAD
CA397654164 rs1173346907	230	R>W		No	ClinGen TOPMed
rs1199536788 CA397654156	231	K>R		No	ClinGen TOPMed gnomAD
rs930045639 CA286942911	232	M>L		No	ClinGen Ensembl
rs1342045707 CA397654136	234	G>R		No	ClinGen gnomAD
CA397654122 rs1292764717	236	L>I		No	ClinGen TOPMed gnomAD
CA8284809 rs777411628	237	M>I		No	ClinGen ExAC gnomAD
rs202243507 CA397654116 CA8284810	237	M>L		No	ClinGen ESP ExAC TOPMed gnomAD
rs900829748 CA286942903	237	M>R		No	ClinGen TOPMed
TCGA novel	238	Y>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1171179895 CA397654095	240	F>V		No	ClinGen gnomAD
CA8284807 rs752396406	242	I>N		No	ClinGen ExAC gnomAD
CA397654079 rs752396406	242	I>T		No	ClinGen ExAC gnomAD
rs1362356177 CA397654072	243	T>I		No	ClinGen TOPMed
rs1427999737 CA397654066	244	A>D		No	ClinGen gnomAD
CA397654067 rs1427999737	244	A>G		No	ClinGen gnomAD
rs1191062948 CA397654071	244	A>T		No	ClinGen gnomAD
CA286942878 COSM705881 COSM705880 rs889303135	245	E>K	lung Variant assessed as Somatic; impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated NCI-TCGA TOPMed
rs750878615 CA8284804	247	R>Q		No	ClinGen ExAC TOPMed gnomAD
rs1196033304 CA397654049	247	R>W		No	ClinGen TOPMed gnomAD
rs762446311 CA8284802	249	V>A		No	ClinGen ExAC gnomAD
rs765646625 CA8284803	249	V>I		No	ClinGen ExAC gnomAD
rs1249271366 CA397654033	250	S>G		No	ClinGen gnomAD
CA397654014 rs1378513701	252	T>I		No	ClinGen gnomAD
rs771924837 CA8284797	253	A>T	Variant assessed as Somatic; 4.787e-05 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA8284796 rs745668813	253	A>V		No	ClinGen ExAC TOPMed gnomAD
rs749288560 CA8284793	255	T>I		No	ClinGen ExAC gnomAD
CA397653993 rs1398823356	257	G>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs755648223 CA8284791	260	L>V		No	ClinGen ExAC TOPMed gnomAD
rs1477249953 CA397653955	262	Q>R		No	ClinGen TOPMed
rs1473331062 CA397653928	264	T>I		No	ClinGen gnomAD
CA397653923 rs1419493121	265	A>G		No	ClinGen gnomAD
rs769712260 CA8284756	267	H>R		No	ClinGen ExAC gnomAD
CA397653877 rs1445159724	269	N>S		No	ClinGen TOPMed gnomAD
CA397653876 rs1445159724	269	N>T		No	ClinGen TOPMed gnomAD
rs1597618089 CA397653847	271	K>N		No	ClinGen Ensembl
CA397653851 rs1283484486	271	K>R		No	ClinGen TOPMed gnomAD
CA397653831 rs1484249442	273	A>G		No	ClinGen TOPMed
CA8284752 rs200340260	273	A>S		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs200340260 CA8284753	273	A>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD
rs1291279785 CA397653821	274	S>I		No	ClinGen gnomAD
CA397653809 rs1355120132	275	P>S		No	ClinGen gnomAD
rs200260191 CA8284750	276	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
COSM1211988 COSM1211987 rs1325127440 CA397653795	276	R>H	Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated NCI-TCGA gnomAD
CA397653802 rs200260191	276	R>S		No	ClinGen ESP ExAC TOPMed gnomAD
rs1318259011 CA397653783	277	F>C		No	ClinGen gnomAD
rs778351446 CA8284748	281	S>C		No	ClinGen ExAC gnomAD
rs778351446 CA397653733	281	S>F		No	ClinGen ExAC gnomAD
rs201192387 CA8284743	287	N>I		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs201192387 CA8284744	287	N>S		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
TCGA novel	288	Q>E	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA8284741 rs190673247	288	Q>H		No	ClinGen 1000Genomes ExAC gnomAD
rs1199486003 CA397653657	288	Q>L		No	ClinGen gnomAD
CA8284740 rs750186200	289	I>F		No	ClinGen ExAC TOPMed gnomAD
CA8284737 rs748663843	291	P>L		No	ClinGen ExAC TOPMed gnomAD
rs748663843 CA286942499	291	P>Q		No	ClinGen ExAC TOPMed gnomAD
CA8284738 rs761686051	291	P>S		No	ClinGen ExAC TOPMed gnomAD
CA397653569 rs1359935327	295	K>R		No	ClinGen gnomAD
rs371156312 CA8284733	298	A>P		No	ClinGen ESP ExAC TOPMed gnomAD
COSM976801 COSM976800 rs371156312 CA8284734	298	A>T	endometrium [Cosmic]	No	ClinGen cosmic curated ESP ExAC TOPMed gnomAD
CA8284732 rs745549139	299	V>A		No	ClinGen ExAC gnomAD
CA397653520 rs1373889510	299	V>L		No	ClinGen gnomAD
rs1440666732 CA397653470	303	K>T		No	ClinGen gnomAD
TCGA novel	304	R>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA397653416 rs1479752009	304	R>S		No	ClinGen gnomAD
COSM976798 CA286942094 rs1042270982 COSM976797	307	R>C	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated NCI-TCGA TOPMed gnomAD
rs1486688798 CA397653382	309	P>L		No	ClinGen gnomAD
CA397653375 rs746019720 CA8284705	310	F>L		No	ClinGen ExAC TOPMed gnomAD
CA397653363 rs1318101839	312	R>T		No	ClinGen gnomAD
rs757533008 CA8284703	314	A>S		No	ClinGen ExAC TOPMed gnomAD
rs757533008 CA397653352	314	A>T		No	ClinGen ExAC TOPMed gnomAD
CA397653342 rs1303896044	315	T>I		No	ClinGen TOPMed
rs1372079320 CA397653341	316	P>T		No	ClinGen gnomAD
rs1379269378 CA397653317	319	V>L		No	ClinGen TOPMed
rs1416301523 CA397653291	322	W>R		No	ClinGen gnomAD
CA8284701 rs763833709	323	T>I		No	ClinGen ExAC gnomAD
CA8284700 rs756058091	324	A>S		No	ClinGen ExAC gnomAD
rs752600034 CA8284699	324	A>V		No	ClinGen ExAC TOPMed gnomAD
rs1418288101 CA397653259	326	Q>E		No	ClinGen TOPMed gnomAD
TCGA novel	326	Q>P	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1418382371	326	Q>R	Variant assessed as Somatic; 0.000118 impact. [NCI-TCGA]	No	NCI-TCGA
CA8284697 rs759122325	327	A>V		No	ClinGen ExAC TOPMed gnomAD
CA397653225 rs1255464194	330	A>T		No	ClinGen gnomAD
rs774092523 CA8284696	331	M>I		No	ClinGen ExAC gnomAD
rs566844565 CA8284694	334	V>L		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs566844565 CA8284693	334	V>M		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA397653183 rs1316679421	335	R>C		No	ClinGen gnomAD
CA286942017 rs553383193	335	R>H		No	ClinGen 1000Genomes TOPMed
CA8284691 rs369945969	338	D>G		No	ClinGen ESP ExAC gnomAD
CA8284689 rs772080746	339	A>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA286941967 rs999073959	341	T>N		No	ClinGen Ensembl
CA397653134 rs1363904039	341	T>S		No	ClinGen gnomAD
TCGA novel	342	S>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA8284687 rs368378574	342	S>W		No	ClinGen ESP ExAC TOPMed gnomAD
rs1295413574 CA397653112	344	L>V		No	ClinGen TOPMed gnomAD
rs749523200 CA8284685	346	Y>C		No	ClinGen ExAC gnomAD
CA286941945 rs901468538	346	Y>N		No	ClinGen Ensembl
rs1463166552 CA397653071	349	H>D		No	ClinGen gnomAD
COSM1302526 rs752614619 COSM1302525 CA8284682	350	I>V	urinary_tract [Cosmic]	No	ClinGen cosmic curated ExAC gnomAD
CA397653054 rs1429216828	351	P>S		No	ClinGen TOPMed gnomAD
CA397653055 rs1429216828	351	P>T		No	ClinGen TOPMed gnomAD
rs1597616631 CA397653017	354	T>P		No	ClinGen Ensembl
rs1162587903 CA397653008	355	R>G		No	ClinGen Ensembl
rs1232072166 CA397653006	355	R>P		No	ClinGen TOPMed gnomAD
rs1232072166 CA397653005	355	R>Q		No	ClinGen TOPMed gnomAD
TCGA novel	359	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA8284655 rs757983008	363	T>M		No	ClinGen ExAC TOPMed gnomAD
COSM976791 rs1392153994 COSM976792 CA397652928	364	T>M	Variant assessed as Somatic; 9.474e-05 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated NCI-TCGA gnomAD
rs761592587 CA8284652	365	R>K		No	ClinGen ExAC gnomAD
CA397652924 rs1480071143	365	R>W		No	ClinGen TOPMed gnomAD
rs767916245 CA286941702	369	R>C		No	ClinGen ExAC TOPMed gnomAD
rs767916245 CA8284650	369	R>G		No	ClinGen ExAC TOPMed gnomAD
rs774872170 CA8284649	369	R>H		No	ClinGen ExAC TOPMed gnomAD
CA8284648 rs774872170	369	R>L		No	ClinGen ExAC TOPMed gnomAD
rs767916245 CA8284651	369	R>S		No	ClinGen ExAC TOPMed gnomAD
CA397652881 rs1377403599	370	K>N		No	ClinGen gnomAD
rs1453162712 CA397652886	370	K>R		No	ClinGen gnomAD
CA397652877 rs1597616540	371	N>T		No	ClinGen Ensembl
rs762956291 CA8284646	373	P>L		No	ClinGen ExAC TOPMed gnomAD
rs373728509 CA8284645	374	E>K		No	ClinGen ESP ExAC TOPMed gnomAD
CA397652838 rs1203745670	375	R>Q		No	ClinGen gnomAD
rs1597616505 CA397652821	376	L>R		No	ClinGen Ensembl
rs1281930358 CA397652812	377	L>V		No	ClinGen gnomAD
CA397652781 rs1208598829	379	E>Q		No	ClinGen gnomAD
rs748445663 CA8284643	380	R>K		No	ClinGen ExAC gnomAD
rs748445663 CA286941632	380	R>T		No	ClinGen ExAC gnomAD
CA8284642 rs776547933	382	I>L		No	ClinGen ExAC gnomAD
CA8284641 rs202115661	382	I>T		No	ClinGen ESP ExAC TOPMed gnomAD
rs776547933 CA397652734	382	I>V		No	ClinGen ExAC gnomAD
CA8284640 rs746873716	383	F>C		No	ClinGen ExAC TOPMed gnomAD
CA397652694 rs1332818542	384	K>R		No	ClinGen gnomAD
rs1332818542 CA397652696	384	K>T		No	ClinGen gnomAD
CA8284610 rs765160567	385	V>M		No	ClinGen ExAC gnomAD
CA8284609 rs761993985	386	H>Y		No	ClinGen ExAC gnomAD
rs1404467638 CA397652404	388	D>E		No	ClinGen gnomAD
rs1162241330 CA397652409	388	D>Y		No	ClinGen gnomAD
rs764403568 CA8284607	391	A>T		No	ClinGen ExAC gnomAD
COSM1381929 CA8284606 rs761016997 COSM1381928	391	A>V	Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA gnomAD
rs376241839 CA286939691	394	T>S		No	ClinGen ESP TOPMed gnomAD
rs1025856941 CA286939678	395	R>G		No	ClinGen TOPMed
rs1469642628 CA397652353	395	R>M		No	ClinGen gnomAD
rs748785564 CA8284600	397	A>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA8284597 rs747849159	398	M>V		No	ClinGen ExAC gnomAD
rs780236660 CA8284596	399	A>T		No	ClinGen ExAC gnomAD
CA397652322 rs1340574569	400	V>I		No	ClinGen TOPMed gnomAD
TCGA novel	401	I>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA8284594 rs147005034	401	I>V		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1373639535 CA397652301	403	G>R		No	ClinGen gnomAD
CA397652302 rs1373639535	403	G>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA397652284 rs1597613169	405	V>G		No	ClinGen Ensembl
CA397652288 rs895833832 CA286939659	405	V>L		No	ClinGen TOPMed gnomAD
rs895833832 CA397652287	405	V>M		No	ClinGen TOPMed gnomAD
CA8284592 rs757903397	406	M>V		No	ClinGen ExAC TOPMed gnomAD
rs753937062 CA8284591	407	A>T		No	ClinGen ExAC gnomAD
CA8284590 rs764317372	410	P>T		No	ClinGen ExAC gnomAD
rs1369464189 CA397652250	411	S>G		No	ClinGen gnomAD
CA397652241 rs1455565845	412	E>K	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA286939632 rs992152787	416	M>L		No	ClinGen TOPMed
rs759389438 CA8284586	416	M>R		No	ClinGen ExAC TOPMed gnomAD
CA8284587 rs759389438	416	M>T		No	ClinGen ExAC TOPMed gnomAD
rs992152787 CA397652211	416	M>V		No	ClinGen TOPMed
CA397652204 rs1233996088	417	Q>*		No	ClinGen TOPMed gnomAD
CA397652202 rs1233666925	417	Q>R		No	ClinGen gnomAD
rs774074883 CA8284585	418	M>V		No	ClinGen ExAC TOPMed gnomAD
rs1264726896 CA397652181	420	I>V		No	ClinGen TOPMed
rs1476585527 CA397652159	422	N>K		No	ClinGen TOPMed
CA8284583 rs762920735	423	N>I		No	ClinGen ExAC gnomAD
CA8284582 rs769320744	424	I>F		No	ClinGen ExAC TOPMed gnomAD
rs769320744 CA8284581	424	I>V		No	ClinGen ExAC TOPMed gnomAD
CA397652146 rs1299594427	425	F>I		No	ClinGen TOPMed gnomAD
rs1373538192	426	F>missing	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	NCI-TCGA
rs201028474 CA8284577	428	L>P		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1357385594 CA397652103	431	D>H		No	ClinGen gnomAD
CA8284575 rs757815512	432	V>I		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	433	R>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1401086451 CA397652089	433	R>Q		No	ClinGen TOPMed gnomAD
CA8284574 rs754416489	434	D>E		No	ClinGen ExAC gnomAD
TCGA novel	434	D>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA8284573 rs777960112	437	K>R		No	ClinGen ExAC TOPMed gnomAD
rs756266614 CA8284572	438	D>H		No	ClinGen ExAC gnomAD
rs756266614 CA397652056	438	D>N		No	ClinGen ExAC gnomAD
CA397652044 rs1275492138	439	F>C		No	ClinGen TOPMed
rs752806033 CA286939579 CA8284571	439	F>L		No	ClinGen ExAC gnomAD
CA8284570 rs767767257	440	G>V		No	ClinGen ExAC TOPMed gnomAD
rs752224729	442	D>G	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	NCI-TCGA
rs752224729	442	D>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	NCI-TCGA
CA8284565 rs762830262	443	V>M		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	444	A>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs369298872 CA286939519	444	A>T		No	ClinGen ESP
rs1246731058 CA397652000	447	V>M		No	ClinGen TOPMed
rs746688846 CA8284559	450	T>I		No	ClinGen ExAC gnomAD
CA397651971 rs771452818	451	N>K		No	ClinGen ExAC TOPMed gnomAD
rs774727415 CA8284558	451	N>S		No	ClinGen ExAC gnomAD
rs1173707778 CA397651970	452	D>N		No	ClinGen gnomAD
rs778439361 CA8284555	456	V>I		No	ClinGen ExAC TOPMed gnomAD
rs756743030 CA8284553	457	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs748257674 CA8284552	457	R>H		No	ClinGen ExAC gnomAD
CA8284550 rs200119825	458	T>K		No	ClinGen ExAC TOPMed gnomAD
rs200119825 CA8284551	458	T>M		No	ClinGen ExAC TOPMed gnomAD
CA8284546 rs750272370	461	A>T		No	ClinGen ExAC gnomAD
CA8284545 rs765150202	461	A>V		No	ClinGen ExAC gnomAD
CA397651893 rs1273436641	464	V>A		No	ClinGen gnomAD
CA286939383 rs541018167	464	V>M		No	ClinGen 1000Genomes
rs760333307 CA8284541	465	E>K		No	ClinGen ExAC TOPMed gnomAD
CA8284542 rs760333307	465	E>Q		No	ClinGen ExAC TOPMed gnomAD
rs775286957 CA8284540	466	G>E		No	ClinGen ExAC TOPMed gnomAD
CA397651866 rs1382687884	469	T>A	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA8284537 rs376230487	469	T>M		No	ClinGen ESP ExAC TOPMed gnomAD
CA8284538 rs376230487	469	T>R		No	ClinGen ESP ExAC TOPMed gnomAD
rs781287655 CA8284534	472	T>M		No	ClinGen ExAC gnomAD
rs1366776360 CA397651839	474	V>L		No	ClinGen TOPMed gnomAD
CA397651833 rs1252032975	475	V>M		No	ClinGen TOPMed
rs1164204703 CA397651825	476	D>G		No	ClinGen gnomAD
rs1597612700 CA397651818	477	Y>S		No	ClinGen Ensembl
rs1429591717 CA397651810	478	R>H		No	ClinGen gnomAD
rs1186998958 CA397651806	479	G>S		No	ClinGen TOPMed gnomAD
rs747191483 CA8284532	480	Y>C		No	ClinGen ExAC TOPMed gnomAD
rs747191483 CA8284533	480	Y>F		No	ClinGen ExAC TOPMed gnomAD
CA397651794 rs1487328493	481	R>Q		No	ClinGen gnomAD
rs868708851 CA286939320	481	R>W		No	ClinGen Ensembl
rs1182801165 CA397651791	482	V>L		No	ClinGen Ensembl
COSM1381927 rs950000630 CA286939304 COSM1381926	483	T>M	Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated NCI-TCGA TOPMed gnomAD
rs1295297995 CA397651780	484	A>T		No	ClinGen gnomAD
rs1371423708 CA397651762	486	S>C		No	ClinGen gnomAD
rs778726369 CA8284528	489	P>S		No	ClinGen ExAC TOPMed gnomAD
rs938041772 CA286939266	490	G>S		No	ClinGen TOPMed gnomAD
rs760115603 CA8284524	493	E>D		No	ClinGen ExAC gnomAD
rs752313367 CA8284523	494	R>Q		No	ClinGen ExAC TOPMed gnomAD
rs1396045346 CA397651716	494	R>W		No	ClinGen TOPMed gnomAD
rs773692220 CA8284520	495	D>E		No	ClinGen ExAC TOPMed gnomAD
rs767276034 CA8284522	495	D>H		No	ClinGen ExAC gnomAD
rs767276034 CA397651712	495	D>N		No	ClinGen ExAC gnomAD
rs756886282 CA286939244	498	Q>H		No	ClinGen Ensembl
CA397651676 rs1271914066	500	V>I		No	ClinGen TOPMed gnomAD
rs770080040 CA8284519	501	I>L		No	ClinGen ExAC gnomAD
rs770080040 CA397651670	501	I>V		No	ClinGen ExAC gnomAD
rs1230803765 CA397651653	503	G>D		No	ClinGen gnomAD
rs926679907 CA286939233	504	S>F		No	ClinGen Ensembl
CA397651644 rs1329507114	505	I>V		No	ClinGen TOPMed gnomAD
CA8284517 rs368267473 COSM50827	506	D>N	breast [Cosmic]	No	ClinGen cosmic curated ESP ExAC TOPMed gnomAD
CA8284515 rs541969235	508	G>R		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs541969235 CA397651623	508	G>S		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1174610097 CA397651607	510	T>I		No	ClinGen gnomAD
CA397651598 rs1377488907	512	V>M		No	ClinGen gnomAD
rs1182046214 CA397651590	513	S>A		No	ClinGen gnomAD
CA8284512 rs746108210	514	H>N		No	ClinGen ExAC TOPMed gnomAD
CA286939155 rs778638092	515	P>L		No	ClinGen ExAC TOPMed gnomAD
CA8284511 rs778638092	515	P>R		No	ClinGen ExAC TOPMed gnomAD
CA397651579 rs1248926263	515	P>S		No	ClinGen gnomAD
rs753750953 CA397651572	516	R>L		No	ClinGen ExAC TOPMed gnomAD
rs753750953 CA8284509	516	R>Q		No	ClinGen ExAC TOPMed gnomAD
CA286939151 rs376492921	517	Y>H		No	ClinGen ESP TOPMed gnomAD
rs1292135683 CA397651554	519	E>A		No	ClinGen TOPMed
CA397651555 rs1292135683	519	E>G		No	ClinGen TOPMed
rs752225113 CA8284506	522	E>G		No	ClinGen ExAC TOPMed gnomAD
CA8284504 rs201123979	523	R>C		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA8284505 rs201123979	523	R>G		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs554152603 CA8284503	523	R>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
CA286939115 rs554152603	523	R>P		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs762101736 CA8284501	525	S>G		No	ClinGen ExAC TOPMed gnomAD
CA397651517 rs769008971	526	R>P		No	ClinGen ExAC TOPMed gnomAD
rs769008971 CA8284499	526	R>Q		No	ClinGen ExAC TOPMed gnomAD
rs777116409 CA8284500	526	R>W	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs1478877401 CA397651514	527	P>S		No	ClinGen TOPMed
rs370078409 CA286939107	528	L>F		No	ClinGen ESP
CA397651492 rs1409320679	530	I>S		No	ClinGen TOPMed gnomAD
CA8284497 rs775496210 COSM1381925 COSM1381924	532	R>Q	Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA gnomAD
COSM976773 CA286939102 COSM976774 rs867623639	532	R>W	Variant assessed as Somatic; 0.0 impact. liver endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated NCI-TCGA gnomAD
CA8284495 rs746021839	533	H>Q		No	ClinGen ExAC gnomAD
CA8284494 rs774449158	534	Q>E		No	ClinGen ExAC TOPMed gnomAD
CA8284493 rs771177971	535	V>L		No	ClinGen ExAC TOPMed gnomAD
rs373340704 CA286939070 COSM705882 COSM705883	537	N>S	lung [Cosmic]	No	ClinGen cosmic curated ESP
rs369972919 CA286939039	538	D>H		No	ClinGen ESP ExAC TOPMed gnomAD
rs369972919 CA8284490	538	D>N		No	ClinGen ESP ExAC TOPMed gnomAD
rs369972919 CA8284491	538	D>Y		No	ClinGen ESP ExAC TOPMed gnomAD
CA397651443 rs1286076754	539	R>C		No	ClinGen gnomAD
CA8284489 rs202134792	539	R>H		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA397651435 rs780812466	540	D>E		No	ClinGen ExAC TOPMed gnomAD
CA286939012 rs926626019	540	D>G		No	ClinGen gnomAD
rs754543242 CA286938993	541	E>*		No	ClinGen ExAC TOPMed gnomAD
CA8284487 rs754543242	541	E>K		No	ClinGen ExAC TOPMed gnomAD
rs1386976308 CA397651405	545	L>V		No	ClinGen gnomAD
CA397651396 rs1461681349	546	C>Y		No	ClinGen gnomAD
rs1160976271 CA397651386	547	S>F		No	ClinGen gnomAD
rs1472404251 CA397651380	548	S>L		No	ClinGen gnomAD
TCGA novel	554	I>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA397651335 rs1247228826	555	I>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA397651319 rs1452429106	557	N>S		No	ClinGen gnomAD
CA8284481 rs761128099	559	G>R		No	ClinGen ExAC TOPMed gnomAD
rs1298969080 CA397651299	560	R>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA8284480 rs775978796	561	H>R		No	ClinGen ExAC TOPMed gnomAD
rs1420895549 CA397651294	561	H>Y		No	ClinGen Ensembl
rs773422187 CA8284478	563	I>L		No	ClinGen ExAC TOPMed gnomAD
rs773422187 CA8284477	563	I>V		No	ClinGen ExAC TOPMed gnomAD
CA397651271 rs1261079884	564	L>H		No	ClinGen TOPMed
TCGA novel	565	D>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs61297645 CA286938919	566	L>M	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs1404259227 CA397651259	566	L>Q		No	ClinGen gnomAD
CA8284472 rs748034531	568	R>C		No	ClinGen ExAC TOPMed gnomAD
rs1447635689 CA397651250	568	R>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs755026813 CA8284470	569	T>I		No	ClinGen ExAC gnomAD
rs554613751 CA397651238	570	F>L		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs955581280 CA286938895	570	F>L		No	ClinGen Ensembl
rs868053601 CA286938884	570	F>S		No	ClinGen TOPMed
rs1052966322 CA286938883	571	P>L		No	ClinGen TOPMed
CA8284467 rs757934910	572	P>A		No	ClinGen ExAC TOPMed gnomAD
rs374090140 CA8284466 COSM294490	572	P>L	large_intestine Variant assessed as Somatic; 0.0001954 impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD
CA286938877 rs374090140	572	P>R		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1207897219 CA397651221	574	L>I		No	ClinGen gnomAD
rs1220183073 CA397651189	578	P>L		No	ClinGen gnomAD
rs1016602885 CA286938824	579	V>G		No	ClinGen TOPMed
CA286938827 rs892760018	579	V>M		No	ClinGen TOPMed gnomAD
rs1350544748 CA397651182	580	P>S		No	ClinGen gnomAD
CA8284459 rs766504135	581	G>S		No	ClinGen ExAC TOPMed gnomAD
rs763046951 CA8284458	582	E>K	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs1176445681 CA397651169	582	E>V		No	ClinGen gnomAD
CA397651161 rs1415946516	583	E>V		No	ClinGen gnomAD
CA397651149 rs761691342	585	P>L		No	ClinGen ExAC TOPMed gnomAD
CA8284455 rs761691342	585	P>R		No	ClinGen ExAC TOPMed gnomAD
rs1252572644 CA397651151	585	P>S		No	ClinGen gnomAD
CA397651148 rs1482323634	586	E>Q		No	ClinGen TOPMed gnomAD
TCGA novel	587	E>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1314305468 CA397651129	588	C>Y		No	ClinGen TOPMed gnomAD
CA397651122 rs779387700	589	A>D		No	ClinGen ExAC gnomAD
rs746985052 CA8284452	589	A>S		No	ClinGen ExAC gnomAD
rs779387700 CA8284451	589	A>V		No	ClinGen ExAC gnomAD
rs771613561 CA8284450	590	R>C		No	ClinGen ExAC TOPMed gnomAD
CA397651120 rs771613561	590	R>G		No	ClinGen ExAC TOPMed gnomAD
CA8284449 COSM976768 rs745452744 COSM976767	590	R>H	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
rs771613561 CA286938734	590	R>S		No	ClinGen ExAC TOPMed gnomAD
rs756970668 CA8284447	591	A>G		No	ClinGen ExAC gnomAD
CA8284448 rs145919520	591	A>T		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs781586263 CA8284445	592	G>S		No	ClinGen ExAC TOPMed gnomAD
CA286938674 rs1055596560	593	F>L		No	ClinGen Ensembl
rs1412983936 CA397651105	593	F>Y		No	ClinGen gnomAD
CA8284443 rs752140443	595	R>C		No	ClinGen ExAC TOPMed gnomAD
CA8284442 rs368591249	595	R>H		No	ClinGen ESP ExAC TOPMed gnomAD
CA397651094 rs752140443	595	R>S		No	ClinGen ExAC TOPMed gnomAD
rs1479897415 CA397651087	596	A>G		No	ClinGen TOPMed
rs1182918433 CA397651090	596	A>T		No	ClinGen gnomAD
CA286938660 rs868569504	597	H>N		No	ClinGen TOPMed
rs1484538412 CA397651081	597	H>R		No	ClinGen gnomAD
CA397651083 rs868569504	597	H>Y		No	ClinGen TOPMed
CA8284439 rs762171639	598	R>P		No	ClinGen ExAC gnomAD
CA8284438 rs762171639	598	R>Q		No	ClinGen ExAC gnomAD
rs750528964 CA8284441	598	R>W		No	ClinGen ExAC TOPMed gnomAD
rs867137301 CA286938637	600	K>N		No	ClinGen gnomAD
CA397651063 rs1269610872	600	K>R		No	ClinGen gnomAD
rs1327829219 CA397651060	601	L>F		No	ClinGen TOPMed gnomAD
rs768600549 CA397651042	603	C>F		No	ClinGen ExAC gnomAD
rs768600549 CA8284436	603	C>Y		No	ClinGen ExAC gnomAD
rs1301977533 CA397651036	604	L>P		No	ClinGen gnomAD
rs1301977533 CA397651035	604	L>Q		No	ClinGen gnomAD
CA397651031 rs1390636043	605	R>H		No	ClinGen gnomAD
rs771960366 CA8284433	606	Q>R		No	ClinGen ExAC TOPMed gnomAD
CA8284432 rs745378304	609	V>L		No	ClinGen ExAC TOPMed gnomAD
rs561955561 CA286938606	611	A>G		No	ClinGen 1000Genomes
CA397650995 rs1426004980	611	A>T		No	ClinGen gnomAD
CA397650981 rs1291521208	613	V>L		No	ClinGen TOPMed
rs1219555130 CA397650972	614	E>G		No	ClinGen gnomAD
CA397650961 rs1354838831	615	H>D		No	ClinGen TOPMed
CA397650956 rs1219316685	615	H>R		No	ClinGen TOPMed
CA397650944 rs1450472987	616	R>K		No	ClinGen TOPMed gnomAD
CA397650602 rs1302237075	616	R>S		No	ClinGen gnomAD
CA397650600 rs1469226618	617	Y>H		No	ClinGen TOPMed gnomAD
CA397650594 rs1597609502	617	Y>S		No	ClinGen Ensembl
rs759449418 CA8284415	618	L>F		No	ClinGen ExAC TOPMed gnomAD
CA397650572 rs773792167	619	L>F		No	ClinGen ExAC TOPMed gnomAD
CA8284414 rs773792167	619	L>V		No	ClinGen ExAC TOPMed gnomAD
rs376055316 CA8284412	621	M>T		No	ClinGen ESP ExAC TOPMed
rs1461787302 CA397650504	624	A>T		No	ClinGen gnomAD
CA8284409 rs747365123	625	A>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA397650481 rs1393769717	626	L>V		No	ClinGen TOPMed
CA8284406 rs746386839	629	M>K		No	ClinGen ExAC gnomAD
CA8284405 rs779099805	630	Q>E		No	ClinGen ExAC TOPMed gnomAD
rs1385259512 CA397650424	630	Q>R		No	ClinGen TOPMed
rs754022152 CA397650388	632	N>K		No	ClinGen ExAC TOPMed gnomAD
rs764348573 CA8284402	633	A>S		No	ClinGen ExAC TOPMed gnomAD
rs764348573 CA397650381	633	A>T		No	ClinGen ExAC TOPMed gnomAD
RCV000832606 VAR_034008 rs11078312 CA8284401	633	A>V		No	ClinGen ClinVar UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
rs767230061 CA8284398	638	T>N		No	ClinGen ExAC gnomAD
CA397650309 rs202041659	639	P>A		No	ClinGen ESP ExAC TOPMed gnomAD
CA397650304 rs1391365129	639	P>R		No	ClinGen gnomAD
CA8284396 rs202041659	639	P>S		No	ClinGen ESP ExAC TOPMed gnomAD
rs769480484 CA8284392	641	S>C		No	ClinGen ExAC TOPMed gnomAD
rs769480484 CA397650279	641	S>F		No	ClinGen ExAC TOPMed gnomAD
CA397650275 rs1428180675	642	L>V		No	ClinGen gnomAD
rs1207121685 CA397650246	644	N>I		No	ClinGen TOPMed
rs1159519474 CA397650242	645	G>R		No	ClinGen gnomAD
CA8284389 rs372787968	646	G>S		No	ClinGen 1000Genomes ESP ExAC gnomAD
CA8284387 rs772357321	647	P>L		No	ClinGen ExAC gnomAD
CA397650230 rs1442952242	647	P>S		No	ClinGen TOPMed gnomAD
rs746331794 CA8284386	648	S>F	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA8284384 rs757881135	651	E>*		No	ClinGen ExAC gnomAD
rs544624679 CA8284383	654	S>F		No	ClinGen 1000Genomes ExAC gnomAD
rs756302003 CA8284381	656	D>E		No	ClinGen ExAC TOPMed gnomAD
rs777773386 CA286936106	656	D>G		No	ClinGen ExAC gnomAD
CA397650152 rs1277908002	656	D>H		No	ClinGen gnomAD
rs777773386 CA8284382	656	D>V		No	ClinGen ExAC gnomAD
rs767303195 CA8284379	657	P>L		No	ClinGen ExAC gnomAD
CA8284380 rs752867461	657	P>T		No	ClinGen ExAC gnomAD
CA397650104 rs1363810257	660	Q>L		No	ClinGen TOPMed
rs754789299 CA8284378	662	A>V		No	ClinGen ExAC TOPMed gnomAD
CA397650068 rs1458531673	663	G>E		No	ClinGen gnomAD
rs1597609117 CA397650047	664	S>R		No	ClinGen Ensembl
rs1444109652 CA397650045	665	E>K		No	ClinGen gnomAD
CA8284376 rs201247106	666	E>K		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1157511677 CA397650004	668	G>S		No	ClinGen gnomAD
CA397649998 rs1597609089	668	G>V		No	ClinGen Ensembl
CA397649995 rs1388536747	669	S>G		No	ClinGen TOPMed
CA286936058 rs553038940	669	S>I		No	ClinGen 1000Genomes gnomAD
TCGA novel	669	S>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA8284373 rs1378741848	671	A>T		No	ClinGen TOPMed gnomAD
rs1331712396 CA397649944	672	S>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
CA397649936 rs1567585541	673	G>A		No	ClinGen Ensembl
CA397649939 rs749931959	673	G>R		No	ClinGen ExAC TOPMed gnomAD
CA8284372 rs749931959	673	G>S		No	ClinGen ExAC TOPMed gnomAD
rs1248458854 CA397649930	674	L>Q		No	ClinGen gnomAD
CA397649909 rs1215976928	676	K>E		No	ClinGen TOPMed
rs1215976928 CA397649911	676	K>Q		No	ClinGen TOPMed
rs1009048443 CA397649905	676	K>R		No	ClinGen TOPMed gnomAD
CA286936032 rs1009048443	676	K>T		No	ClinGen TOPMed gnomAD
rs1597608985 CA397649887	677	V>G		No	ClinGen Ensembl
CA8284371 rs371258450	677	V>M		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA8284370 rs761490405	679	E>K		No	ClinGen ExAC gnomAD
rs1196945381 CA397649838	683	T>I		No	ClinGen TOPMed
rs554951409 CA8284368	684	I>V		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA286936018 rs868410232	685	A>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
CA8284365 rs771552882	686	A>E		No	ClinGen ExAC TOPMed gnomAD
CA397649824 rs1436775008	686	A>S		No	ClinGen TOPMed gnomAD
rs1436775008 CA397649826	686	A>T		No	ClinGen TOPMed gnomAD
rs748351806 CA8284361	689	G>R		No	ClinGen ExAC TOPMed gnomAD
rs748351806 CA8284362	689	G>S		No	ClinGen ExAC TOPMed gnomAD
CA8284360 rs781246965	690	T>I		No	ClinGen ExAC gnomAD
CA397649797 rs781246965	690	T>R		No	ClinGen ExAC gnomAD
rs1597608457 CA397649774	691	D>A		No	ClinGen Ensembl
CA8284359 rs755230147	691	D>Y		No	ClinGen ExAC gnomAD
rs753276441 CA8284334	692	P>L		No	ClinGen ExAC
CA8284332 rs755760596	693	R>P		No	ClinGen ExAC TOPMed gnomAD
rs755760596 CA397649764	693	R>Q		No	ClinGen ExAC TOPMed gnomAD
CA8284333 rs763712121	693	R>W		No	ClinGen ExAC TOPMed gnomAD
CA397649753 rs752429645	695	R>P		No	ClinGen ExAC TOPMed gnomAD
CA8284331 rs752429645	695	R>Q		No	ClinGen ExAC TOPMed gnomAD
rs200794784 CA286935799	695	R>W		No	ClinGen gnomAD
rs371577642 CA397649751	696	E>K		No	ClinGen ESP ExAC gnomAD
rs371577642 COSM1728539 CA8284330 COSM1728540	696	E>Q	liver [Cosmic]	No	ClinGen cosmic curated ESP ExAC gnomAD
CA397649744 rs1480150172	697	V>M		No	ClinGen TOPMed gnomAD
CA8284329 rs763203980	699	R>C		No	ClinGen ExAC TOPMed gnomAD
rs763203980 CA286935794	699	R>G		No	ClinGen ExAC TOPMed gnomAD
rs1184946588 CA397649730	699	R>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs1232626175 CA397649724	700	N>S		No	ClinGen gnomAD
rs373602317 CA8284327	701	A>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
rs865802338 CA286935777	701	A>V		No	ClinGen TOPMed gnomAD
rs776630214 CA8284325	702	C>S		No	ClinGen ExAC gnomAD
CA397649712 rs1289705149	702	C>S		No	ClinGen TOPMed gnomAD
rs530686223 CA8284324	703	K>E		No	ClinGen 1000Genomes ExAC gnomAD
rs775671938 CA8284322	704	A>T		No	ClinGen ExAC gnomAD
CA8284321 rs182611545	704	A>V		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1228439531 CA397649693	705	V>G		No	ClinGen TOPMed
rs745649184 CA8284320	705	V>I		No	ClinGen ExAC gnomAD
CA286935720 rs745874735	706	G>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
CA286935718 rs1036300624	710	S>G		No	ClinGen Ensembl
rs1417782443 CA397649663	710	S>T		No	ClinGen gnomAD
CA397649651 rs1183013515	712	A>T		No	ClinGen gnomAD
CA8284315 rs191289430	712	A>V		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs369055373 CA397649641	713	F>L		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs767245609 CA8284313	714	D>N		No	ClinGen ExAC TOPMed gnomAD
CA397649626 rs1465092735	716	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA397649612 rs1213047620	718	N>H		No	ClinGen gnomAD
rs1315869621 CA397649602	719	P>S		No	ClinGen gnomAD
CA397649597 rs1290497059	720	D>H		No	ClinGen gnomAD
CA286935700 rs1045743170	721	I>V		No	ClinGen TOPMed gnomAD
CA286935699 rs943716413	722	F>I		No	ClinGen TOPMed gnomAD
rs1314142869 CA397649572	723	S>L		No	ClinGen gnomAD
CA286935694 rs770832952	724	P>L		No	ClinGen TOPMed gnomAD
CA8284312 rs754725515	724	P>S		No	ClinGen ExAC gnomAD
rs1198964783 CA397649548	726	V>F		No	ClinGen TOPMed
rs1198964783 CA397649550	726	V>I		No	ClinGen TOPMed
TCGA novel	726	V>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA397649542 rs1378915025	727	R>C		No	ClinGen TOPMed
CA397649541 rs1461116886	727	R>H		No	ClinGen gnomAD
rs1178217326 CA397649525	729	P>L		No	ClinGen gnomAD
CA397649528 rs1289583714	729	P>S		No	ClinGen gnomAD
CA8284293 rs751224802	730	E>D		No	ClinGen ExAC TOPMed gnomAD
CA397649515 rs1171677359	731	S>A		No	ClinGen TOPMed
CA397649508 rs1388886947	732	C>Y		No	ClinGen TOPMed
CA286935532 rs866190364	733	Q>K		No	ClinGen Ensembl
CA8284290 rs754245319	734	D>G		No	ClinGen ExAC TOPMed gnomAD
CA397649492 rs754245319	734	D>V		No	ClinGen ExAC TOPMed gnomAD
rs372428349 CA286935525	737	R>L		No	ClinGen ESP ExAC TOPMed gnomAD
rs372428349 CA8284288	737	R>Q		No	ClinGen ESP ExAC TOPMed gnomAD
rs200722517 CA8284289	737	R>W		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs758857015 CA8284287	738	D>N		No	ClinGen ExAC gnomAD
rs1338059161 CA397649431	744	K>E		No	ClinGen gnomAD
rs944923887 CA397649418	745	D>E		No	ClinGen TOPMed gnomAD
CA397649415 rs550325305	746	A>S		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs550325305 CA8284284	746	A>T		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA286935483 rs1032419736	746	A>V		No	ClinGen TOPMed gnomAD
rs866478571 CA397649411	747	A>P		No	ClinGen TOPMed gnomAD
CA286935471 rs866478571	747	A>S		No	ClinGen TOPMed gnomAD
CA8284282 rs762810140	748	A>G		No	ClinGen ExAC gnomAD
rs953092769 CA286935466	748	A>S		No	ClinGen gnomAD
rs953092769 CA397649406	748	A>T		No	ClinGen gnomAD
CA397649398 rs1361982638	749	F>C		No	ClinGen gnomAD
CA397649395 rs1424141584	750	L>M		No	ClinGen gnomAD
rs1244794141 CA397649388	751	L>F		No	ClinGen gnomAD
CA397649389 rs1244794141	751	L>V		No	ClinGen gnomAD
CA397649355 rs1205810529	756	P>T		No	ClinGen gnomAD
rs1353006641 CA397649348	757	G>S		No	ClinGen gnomAD
rs530626304 CA8284278	758	L>W		No	ClinGen 1000Genomes ExAC gnomAD
CA397649311 rs1260661075	761	D>H		No	ClinGen TOPMed
CA8284264 rs773080711	761	D>V		No	ClinGen ExAC gnomAD
CA397649023 rs1490282163	762	C>*		No	ClinGen gnomAD
CA8284262 rs780717065	763	M>L		No	ClinGen ExAC TOPMed gnomAD
CA8284261 rs776649428	763	M>R		No	ClinGen ExAC gnomAD
CA8284263 rs780717065	763	M>V		No	ClinGen ExAC TOPMed gnomAD
rs1337049426 CA397649006	764	E>K		No	ClinGen gnomAD
CA8284257 rs771657609	766	A>G		No	ClinGen ExAC TOPMed gnomAD
rs201703032 CA397648976	766	A>S		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
COSM1381915 rs201703032 CA8284259 COSM1381916	766	A>T	large_intestine [Cosmic]	No	ClinGen cosmic curated 1000Genomes ESP ExAC TOPMed gnomAD
rs771657609 CA8284258	766	A>V		No	ClinGen ExAC TOPMed gnomAD
CA8284253 CA8284252 rs368772841	770	V>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs368772841 CA8284254	770	V>M		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1167621804 CA397648919	772	G>R		No	ClinGen gnomAD
CA8284250 rs751644085	774	T>A		No	ClinGen ExAC gnomAD
CA8284249 rs374759051	774	T>K		No	ClinGen ESP ExAC TOPMed gnomAD
rs374759051 CA8284248	774	T>M		No	ClinGen ESP ExAC TOPMed gnomAD
rs1271846459 CA397648839	779	M>I		No	ClinGen gnomAD
CA8284245 rs776361105	780	R>C		No	ClinGen ExAC TOPMed gnomAD
CA8284244 rs776361105	780	R>G		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	780	R>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs372747520 CA8284243	780	R>H		No	ClinGen ESP ExAC TOPMed gnomAD
rs894873703 CA286934783	781	Q>H		No	ClinGen gnomAD
rs1280839980 CA397648831	781	Q>K		No	ClinGen gnomAD
CA286934759 rs936484411	782	R>Q		No	ClinGen TOPMed gnomAD
rs367657982 CA286934769	782	R>W		No	ClinGen ESP ExAC TOPMed gnomAD
rs867349762 CA286934756	784	I>V		No	ClinGen Ensembl
rs775001603 CA8284241	785	N>S		No	ClinGen ExAC gnomAD
rs1481387862 CA397648798	786	M>I		No	ClinGen TOPMed
CA397648801 rs1334987551	786	M>T		No	ClinGen gnomAD
rs1439743194 CA397648803	786	M>V		No	ClinGen TOPMed gnomAD
COSM3722264 COSM3722263 CA286934750 rs925101230	787	R>C	upper_aerodigestive_tract Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated NCI-TCGA gnomAD
rs1268969803 COSM1381913 CA397648793 COSM1381914	787	R>H	large_intestine Variant assessed as Somatic; impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated NCI-TCGA TOPMed gnomAD
rs376068167 CA8284240	788	Y>*		No	ClinGen ESP ExAC TOPMed gnomAD
rs200277514 CA8284239	789	L>V		No	ClinGen ESP ExAC TOPMed gnomAD
rs1383287324 CA397648769	791	K>R		No	ClinGen TOPMed
CA8284238 rs773972027	792	V>L		No	ClinGen ExAC gnomAD
CA8284237 rs770611203	794	E>D		No	ClinGen ExAC TOPMed gnomAD
rs1444094093 CA397648754	794	E>Q		No	ClinGen TOPMed
CA8284234 rs369124420 CA8284235	796	V>L		No	ClinGen ESP ExAC TOPMed gnomAD
rs373453394 CA8284232	798	R>Q		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs376707057 CA8284233	798	R>W	Variant assessed as Somatic; 9.331e-05 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
CA8284231 rs199770675	799	S>C		No	ClinGen 1000Genomes ExAC gnomAD
CA397648729 rs750577311	799	S>N		No	ClinGen ExAC gnomAD
CA8284230 rs750577311	799	S>T		No	ClinGen ExAC gnomAD
rs975239141 CA286934690	800	P>L		No	ClinGen TOPMed gnomAD
rs975239141 CA397648722	800	P>Q		No	ClinGen TOPMed gnomAD
CA397648719 rs562629566	801	A>S		No	ClinGen TOPMed gnomAD
CA286934689 rs562629566	801	A>T		No	ClinGen TOPMed gnomAD
CA8284227 rs544644539	801	A>V		No	ClinGen ExAC TOPMed gnomAD
CA8284225 rs377116592	802	R>C		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA8284226 rs377116592	802	R>G		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA8284224 rs570575594	802	R>H		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA397648712 rs886666146	803	H>D		No	ClinGen TOPMed gnomAD
CA286934678 rs886666146	803	H>Y		No	ClinGen TOPMed gnomAD
CA8284221 rs114233864	808	V>I		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA8284220 rs770555752	809	F>S		No	ClinGen ExAC gnomAD
rs370270067 CA8284182	812	G>S		No	ClinGen ESP ExAC TOPMed gnomAD
rs764790223 CA8284181	812	G>V		No	ClinGen ExAC gnomAD
rs775933092 CA8284179	818	T>I		No	ClinGen ExAC gnomAD
rs760076057 CA8284177	819	R>C		No	ClinGen ExAC TOPMed gnomAD
CA286934538 rs764234556	820	S>A		No	ClinGen TOPMed
CA8284176 rs774699615	820	S>L		No	ClinGen ExAC gnomAD
CA397648560 rs1167966578	824	I>T		No	ClinGen gnomAD
rs769848334 COSM1381911 COSM1381912 CA8284172	827	T>M	Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
CA286934513 rs1029911762	830	Q>E		No	ClinGen TOPMed gnomAD
rs912971502 CA286934374	831	G>A		No	ClinGen TOPMed gnomAD
CA397648500 rs912971502	831	G>E		No	ClinGen TOPMed gnomAD
rs763835128 CA8284142	831	G>R		No	ClinGen ExAC gnomAD
rs766769624 CA8284139	834	L>F		No	ClinGen ExAC gnomAD
rs750962337 CA8284137	835	S>T		No	ClinGen ExAC gnomAD
CA397648474 rs1445078084	836	G>S		No	ClinGen TOPMed gnomAD
CA397648460 rs1185700954	838	S>P		No	ClinGen gnomAD
CA8284134 rs776754848	840	A>S		No	ClinGen ExAC TOPMed gnomAD
CA397648450 rs776754848	840	A>T		No	ClinGen ExAC TOPMed gnomAD
CA397648446 rs1245546154	840	A>V		No	ClinGen TOPMed
rs768848817 CA8284133	841	I>V		No	ClinGen ExAC gnomAD
CA8284132 rs760959588	842	S>N		No	ClinGen ExAC gnomAD
rs745704208 CA8284129	848	F>L		No	ClinGen ExAC TOPMed gnomAD
rs748795142 CA397648295	850	S>N		No	ClinGen ExAC TOPMed gnomAD
rs771060137 CA8284127	850	S>R		No	ClinGen ExAC gnomAD
CA8284126 rs748795142	850	S>T		No	ClinGen ExAC TOPMed gnomAD
CA397648290 rs1297575586	851	S>T		No	ClinGen gnomAD
rs755758534 CA8284124	853	P>A		No	ClinGen ExAC gnomAD
rs755758534 CA8284125	853	P>S		No	ClinGen ExAC gnomAD
rs1597604530 CA397648242	854	N>T		No	ClinGen Ensembl
CA8284123 rs752424447	855	P>H		No	ClinGen ExAC gnomAD
CA397648215 rs758768004	856	V>L		No	ClinGen ExAC TOPMed gnomAD
CA8284121 rs758768004	856	V>M		No	ClinGen ExAC TOPMed gnomAD
rs1597604503 CA397648205	857	A>P		No	ClinGen Ensembl
CA397648190 rs1416873505	858	H>D		No	ClinGen TOPMed
rs1597604485 CA397648185	858	H>P		No	ClinGen Ensembl
rs753855649 CA8284117	861	A>D		No	ClinGen ExAC TOPMed gnomAD
rs368569828 CA8284118	861	A>T		No	ClinGen ESP ExAC TOPMed gnomAD
rs1275421188 CA397648130	862	D>A		No	ClinGen Ensembl
rs200041898 CA8284115	862	D>N		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA8284114 rs775762493	863	E>K		No	ClinGen ExAC gnomAD
CA8284113 rs772226566	865	V>F		No	ClinGen ExAC gnomAD
CA8284112 rs759371068	866	S>F		No	ClinGen ExAC TOPMed gnomAD
CA397648031 rs1367163348	869	R>Q		No	ClinGen gnomAD
CA8284110 rs749243306	870	N>K		No	ClinGen ExAC TOPMed gnomAD
CA8284108 rs777376163	871	K>R		No	ClinGen ExAC TOPMed gnomAD
CA397648002 rs777376163	871	K>T		No	ClinGen ExAC TOPMed gnomAD
rs769368085 CA8284107	873	R>K		No	ClinGen ExAC gnomAD
CA8284106 rs529511591	874	K>R		No	ClinGen 1000Genomes ExAC gnomAD
CA397647921 rs1193520130	876	R>Q		No	ClinGen gnomAD
rs899724776 CA286934220	877	P>L		No	ClinGen Ensembl
rs563650432 CA397647918	877	P>S		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA8284105 rs563650432	877	P>T		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs750782828 CA8284103	878	P>L		No	ClinGen ExAC TOPMed gnomAD
CA397647912 rs750782828	878	P>R		No	ClinGen ExAC TOPMed gnomAD
CA8284104 rs754649121	878	P>S		No	ClinGen ExAC gnomAD
CA397647898 rs1273231021	879	G>E		No	ClinGen gnomAD
rs374633371 CA397647894	880	A>S		No	ClinGen ESP ExAC TOPMed gnomAD
CA8284100 rs374633371	880	A>T		No	ClinGen ESP ExAC TOPMed gnomAD
CA286934197 rs941992091	881	A>T		No	ClinGen TOPMed
rs764637954 CA8284099	881	A>V		No	ClinGen ExAC gnomAD
CA397647839 rs371894031	883	N>K		No	ClinGen ESP ExAC TOPMed gnomAD
CA8284097 rs572158133	885	A>P		No	ClinGen ExAC TOPMed gnomAD
CA397647797 rs1336174686	886	W>*		No	ClinGen gnomAD
rs1435496571 CA397647808	886	W>R		No	ClinGen gnomAD
TCGA novel	887	A>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1329769646 CA397647783	887	A>V		No	ClinGen gnomAD
rs368364853 CA8284096	889	M>I		No	ClinGen ESP ExAC TOPMed gnomAD
rs868193862 CA286934187	890	T>A		No	ClinGen Ensembl
rs1567582308 CA397647739	890	T>N		No	ClinGen Ensembl
CA8284095 rs759692447	892	Q>R		No	ClinGen ExAC gnomAD
TCGA novel	892	Q>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA8284094 COSM976753 COSM976752 rs774224207	894	L>I	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA gnomAD
CA397647636 rs766307177	896	K>N		No	ClinGen ExAC gnomAD
rs1233838379 CA397647597	898	I>M		No	ClinGen gnomAD
CA286934159 rs1042776497	903	K>N		No	ClinGen TOPMed gnomAD
rs929376737 CA286934162	903	K>Q		No	ClinGen Ensembl
CA286934158 rs947031516	904	N>I		No	ClinGen TOPMed gnomAD
rs1325154032 CA397647468	907	D>A		No	ClinGen gnomAD
rs773260152 CA397647459	908	F>L		No	ClinGen ExAC gnomAD
rs1597604052 CA397647456	909	D>A		No	ClinGen Ensembl
CA8284089 COSM1211989 rs374551796 COSM1211990	909	D>N	Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD
CA8284090 rs374551796	909	D>Y	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD
rs746666232 CA286934151	911	E>K		No	ClinGen ExAC TOPMed gnomAD
rs746666232 CA8284086	911	E>Q		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	913	E>G	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA397647283 rs78793700	915	V>L		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA8284055 rs78793700	915	V>M		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs780418387 CA8284054	916	D>E		No	ClinGen ExAC gnomAD
rs1477457329 CA397647234	918	A>V		No	ClinGen TOPMed gnomAD
rs1269263782 CA397647227	919	V>M		No	ClinGen TOPMed gnomAD
rs1192695259 CA397647203	920	E>D		No	ClinGen TOPMed gnomAD
rs758747236 CA8284053	921	T>I		No	ClinGen ExAC gnomAD
rs758747236 CA397647195	921	T>N		No	ClinGen ExAC gnomAD
rs1217272212 CA397647161	923	G>D		No	ClinGen gnomAD
rs535658672 CA8284051	923	G>R		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs535658672 CA8284050	923	G>S		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
COSM1194930 rs972796697 COSM1194929 CA286933799	926	K>N	lung [Cosmic]	No	ClinGen cosmic curated TOPMed
rs1388853758 CA397647090	927	I>M		No	ClinGen gnomAD
rs753699065 CA8284049	928	T>M		No	ClinGen ExAC gnomAD
rs1442525924 CA397647072	929	L>F		No	ClinGen gnomAD
CA397647053 rs1464701652	930	L>P		No	ClinGen gnomAD
rs764134004 CA8284048	931	R>L		No	ClinGen ExAC TOPMed
rs764134004 CA397647046	931	R>Q		No	ClinGen ExAC TOPMed
rs1429903193 COSM178387 CA397647049	931	R>W	Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated NCI-TCGA gnomAD
rs1431211551 CA397647025	932	E>D		No	ClinGen gnomAD
rs181923267 CA286933782	933	I>M		No	ClinGen 1000Genomes TOPMed gnomAD
CA397647011 rs1266437901	933	I>S		No	ClinGen gnomAD
rs771659481 CA8284045	934	S>L		No	ClinGen ExAC TOPMed gnomAD
CA8284046 rs775039790	934	S>T		No	ClinGen ExAC gnomAD
rs1317412952 CA397646994	935	L>M		No	ClinGen gnomAD
CA8284043 rs773589149	938	G>V		No	ClinGen ExAC
rs1257073865 CA397646330	940	Q>K		No	ClinGen gnomAD
rs1597602158 CA397646296	941	V>G		No	ClinGen Ensembl
rs546151475 CA8284005	941	V>I		No	ClinGen 1000Genomes ExAC gnomAD
rs772298918 CA8284002	944	K>R		No	ClinGen ExAC gnomAD
CA397646247 rs374987812	948	F>L		No	ClinGen ESP ExAC TOPMed gnomAD
rs779000573 CA8284000	951	R>C		No	ClinGen ExAC gnomAD
CA397646228 rs1425120685	951	R>H		No	ClinGen TOPMed gnomAD
CA397646204 rs1456443570	954	P>R		No	ClinGen gnomAD
rs375997366 CA286933373	955	A>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP NCI-TCGA TOPMed gnomAD
COSM976747 CA8283996 rs756008773 COSM976746	955	A>V	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA gnomAD
rs918414187 CA286933358	958	E>K		No	ClinGen gnomAD
rs1266786328 CA397646172	959	E>D		No	ClinGen TOPMed
CA397646160 rs1258180929	961	V>G		No	ClinGen gnomAD
CA8283991 rs200623081	961	V>M		No	ClinGen ESP ExAC TOPMed gnomAD
CA397646155 rs1220338637	962	L>F		No	ClinGen gnomAD
CA397646121 COSM976743 rs1332669209 COSM976744	967	V>M	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated NCI-TCGA gnomAD
rs1334650747 CA397646091	971	V>A		No	ClinGen Ensembl
CA8283985 rs772775426	971	V>I		No	ClinGen ExAC TOPMed gnomAD
CA286933304 rs1034691708	973	P>A		No	ClinGen Ensembl
CA286933302 rs1002172333	974	K>N		No	ClinGen TOPMed
CA397646064 rs1366869677	975	A>V		No	ClinGen TOPMed
CA397646058 rs1171501346	976	S>L		No	ClinGen TOPMed gnomAD
CA8283983 rs774504607	979	F>L		No	ClinGen ExAC gnomAD
CA8283982 rs770995955	980	H>L		No	ClinGen ExAC
rs770995955 CA286933295	980	H>R		No	ClinGen ExAC
rs1478530025 CA397646005	984	S>G		No	ClinGen gnomAD
rs574404930 CA8283980	984	S>R		No	ClinGen 1000Genomes ExAC gnomAD
CA8283978 rs369927961	987	A>T		No	ClinGen ESP ExAC TOPMed gnomAD
TCGA novel	988	K>Q	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA8283977 rs554292311	989	V>L		No	ClinGen 1000Genomes ExAC gnomAD
CA8283976 rs754996649	991	Q>H		No	ClinGen ExAC gnomAD
rs897288009 CA286933281	992	G>C		No	ClinGen TOPMed gnomAD
rs746999026 CA8283957	992	G>D		No	ClinGen ExAC gnomAD
rs897288009 CA397645951	992	G>R		No	ClinGen TOPMed gnomAD
rs1342153114 COSM3362037 CA397645919 COSM3362036	995	K>R	kidney [Cosmic]	No	ClinGen cosmic curated TOPMed
CA397645913 rs1374714629	996	E>*		No	ClinGen gnomAD
CA397645902 rs1216497584	997	G>V		No	ClinGen TOPMed
rs779381488 CA8283956	998	C>R		No	ClinGen ExAC TOPMed gnomAD
rs1324122612 CA397645898	998	C>Y		No	ClinGen TOPMed
CA397645889 rs1213992537	999	E>V		No	ClinGen gnomAD
CA286933190 rs924462582	1000	L>I		No	ClinGen TOPMed
rs74532258 CA397645870	1002	N>I		No	ClinGen ESP ExAC TOPMed gnomAD
CA8283954 rs74532258	1002	N>S		No	ClinGen ESP ExAC TOPMed gnomAD
rs1332845950 CA397645865	1003	E>K		No	ClinGen gnomAD
CA8283953 rs778697125	1005	L>V		No	ClinGen ExAC gnomAD
rs537415953 CA286933163	1006	N>K		No	ClinGen gnomAD
rs759915226 CA8283949	1011	V>I		No	ClinGen ExAC gnomAD
TCGA novel	1012	Y>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1597601510 CA397645805	1012	Y>S		No	ClinGen Ensembl
rs1435468179 CA397645789	1014	A>V		No	ClinGen TOPMed
CA397645782 rs1488458293	1015	M>I		No	ClinGen gnomAD
rs909528833 CA286933132	1015	M>T		No	ClinGen Ensembl
rs1174566306 CA397645788	1015	M>V		No	ClinGen TOPMed
rs769942085 CA8283944	1017	V>L		No	ClinGen ExAC TOPMed gnomAD
rs769942085 CA397645772	1017	V>M		No	ClinGen ExAC TOPMed gnomAD
CA8283943 rs376805113	1018	E>A		No	ClinGen ESP ExAC TOPMed gnomAD
CA397645762 rs1362018621	1018	E>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
rs776249753 CA8283942	1019	T>N		No	ClinGen ExAC gnomAD
CA397645760 rs1597601457	1019	T>P		No	ClinGen Ensembl
rs746827905 CA8283940	1021	A>T		No	ClinGen ExAC gnomAD
CA8283938 rs771962673	1024	R>C		No	ClinGen ExAC TOPMed gnomAD
rs745317633 CA8283937	1024	R>H		No	ClinGen ExAC TOPMed gnomAD
CA8283936 rs778570568	1025	L>V		No	ClinGen ExAC gnomAD
CA286933103 rs570125559	1026	L>V		No	ClinGen Ensembl
CA397645692 rs1418092369	1027	A>T		No	ClinGen gnomAD
rs571139579 COSM1197198 COSM1197197 CA8283932	1028	R>C	lung [Cosmic]	No	ClinGen cosmic curated 1000Genomes ExAC gnomAD
rs777344374 CA8283931	1028	R>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs571139579 COSM4129749 CA397645663 COSM4129750	1028	R>S	thyroid [Cosmic]	No	ClinGen cosmic curated 1000Genomes ExAC gnomAD
CA397645614 rs1187092215	1030	H>R		No	ClinGen gnomAD
rs1279705489 CA397645536	1032	I>M		No	ClinGen Ensembl
TCGA novel	1034	G>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA397645506 rs1288460123	1034	G>S		No	ClinGen TOPMed
CA397645474 rs1270137266	1035	D>G		No	ClinGen TOPMed
CA8283926 rs750431695	1035	D>N		No	ClinGen ExAC TOPMed gnomAD
CA8283924 rs761973954	1036	Y>C		No	ClinGen ExAC gnomAD
CA8283925 rs765327971	1036	Y>D		No	ClinGen ExAC gnomAD
rs368663085 CA8283922	1037	A>T		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs779386864 CA8283890	1039	A>S		No	ClinGen ExAC gnomAD
rs779386864 CA397645315	1039	A>T		No	ClinGen ExAC gnomAD
rs764112822 CA8283888	1041	S>I		No	ClinGen ExAC TOPMed gnomAD
CA8283887 rs764112822	1041	S>N		No	ClinGen ExAC TOPMed gnomAD
rs200565690 CA8283886	1043	Q>E		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1190446035 CA397645280	1044	Q>R		No	ClinGen TOPMed
rs367587105 CA8283885	1046	A>V		No	ClinGen ESP ExAC TOPMed gnomAD
rs759405260 CA397645263	1047	V>L		No	ClinGen ExAC gnomAD
rs759405260 CA8283883	1047	V>M		No	ClinGen ExAC gnomAD
CA397645248 rs1373395262	1049	M>I		No	ClinGen TOPMed
rs1354536153 CA397645252	1049	M>L		No	ClinGen TOPMed gnomAD
CA397645237 rs1421332984	1051	E>Q		No	ClinGen gnomAD
rs762802291 CA8283880	1052	R>W		No	ClinGen ExAC TOPMed gnomAD
rs1157108519 CA397645210	1055	G>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA8283879 rs772733408	1056	T>I		No	ClinGen ExAC TOPMed gnomAD
rs1369132067 CA397645183	1059	P>T		No	ClinGen gnomAD
rs761434867 CA8283877	1060	N>S		No	ClinGen ExAC gnomAD
rs761434867 CA397645174	1060	N>T		No	ClinGen ExAC gnomAD
rs1257491876 CA397645158	1062	I>M		No	ClinGen gnomAD
CA397645157 rs1194799379	1063	Q>E		No	ClinGen gnomAD
rs1049689788 CA286929143	1064	E>A		No	ClinGen TOPMed
rs768361755 CA8283875	1065	Y>F		No	ClinGen ExAC TOPMed
rs1332547672 CA397645117	1066	M>I		No	ClinGen gnomAD
rs750299603 CA8283844	1072	C>Y		No	ClinGen ExAC gnomAD
rs1264664929 CA397645067	1074	A>S		No	ClinGen Ensembl
rs1453199457 CA397645060	1075	S>N		No	ClinGen gnomAD
CA286928928 rs879131326	1076	S>G		No	ClinGen Ensembl
rs761751463 CA8283842	1077	Q>E		No	ClinGen ExAC gnomAD
CA397645048 rs761751463	1077	Q>K		No	ClinGen ExAC gnomAD
rs753306124 CA8283841	1078	L>M		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	1078	L>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs775094871 CA8283839	1079	S>F		No	ClinGen ExAC gnomAD
CA8283840 rs763617381	1079	S>P		No	ClinGen ExAC gnomAD
rs775094871 CA8283838	1079	S>Y		No	ClinGen ExAC gnomAD
rs1232370983 CA397645033	1080	T>A		No	ClinGen gnomAD
CA397645031 rs1370284805	1080	T>S		No	ClinGen gnomAD
rs372755886 COSM1381894 COSM1381895 CA8283836	1081	A>T	Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD
CA8283834 rs748692718	1084	L>V		No	ClinGen ExAC TOPMed gnomAD
rs995435238 CA397644995	1086	Y>*		No	ClinGen Ensembl
CA397645000 rs1193986740	1086	Y>H		No	ClinGen gnomAD
rs1380581805 CA397644990	1087	R>H		No	ClinGen TOPMed gnomAD
COSM1520363 CA8283830 rs747122833 COSM1520362	1088	A>S	lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated ExAC NCI-TCGA gnomAD
CA286928892 rs747122833	1088	A>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA397644984 rs1468213638	1088	A>V		No	ClinGen TOPMed gnomAD
rs758702771 CA8283828	1089	R>G		No	ClinGen ExAC gnomAD
rs778772369 CA8283826	1092	M>L		No	ClinGen ExAC TOPMed gnomAD
rs778772369 CA397644964	1092	M>V		No	ClinGen ExAC TOPMed gnomAD
rs757138423 CA8283825	1093	L>V		No	ClinGen ExAC gnomAD
rs753753555 CA8283824	1094	L>V		No	ClinGen ExAC gnomAD
rs764060900 CA8283823	1096	F>L		No	ClinGen ExAC gnomAD
CA397644935 rs1357703729	1097	G>R		No	ClinGen gnomAD
CA8283821 rs752312296	1098	E>D		No	ClinGen ExAC TOPMed gnomAD
rs767021925 CA8283820	1099	D>G		No	ClinGen ExAC gnomAD
rs1480959760 CA397644920	1099	D>Y		No	ClinGen gnomAD
CA8283819 rs759235994	1102	E>A		No	ClinGen ExAC gnomAD
rs948916591 CA286928817	1102	E>K		No	ClinGen gnomAD
rs773412751 CA8283818	1103	M>V		No	ClinGen ExAC gnomAD
CA397644884 rs1163727193	1104	A>V		No	ClinGen gnomAD
rs762314998	1107	D>=	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	NCI-TCGA
COSM302475 CA397644828 rs1442398511	1111	G>R	Variant assessed as Somatic; 0.0 impact. central_nervous_system [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated NCI-TCGA gnomAD
CA397644817 rs1452786743	1113	V>M		No	ClinGen TOPMed
CA397644801 rs1356259388	1115	H>L		No	ClinGen gnomAD
rs1409156052 CA397644793	1116	G>E	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
rs1168022275 CA397644790	1117	V>L		No	ClinGen gnomAD
rs1194517607 CA397644692	1121	D>H		No	ClinGen TOPMed gnomAD
rs1194517607 CA397644694	1121	D>N		No	ClinGen TOPMed gnomAD
rs777551831 CA8283783	1121	D>V		No	ClinGen ExAC gnomAD
rs1194517607 CA397644689	1121	D>Y		No	ClinGen TOPMed gnomAD
rs1241641121 CA397644632	1125	R>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs1253634243 CA397644640	1125	R>S		No	ClinGen gnomAD
CA397644593 rs1278809128	1128	E>Q		No	ClinGen gnomAD
TCGA novel	1130	A>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA397644562 rs1368091556	1130	A>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs961961374 CA397644560	1131	L>V		No	ClinGen TOPMed gnomAD
CA8283779 rs374574637	1132	A>S		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs61750787 CA8283778	1132	A>V		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs764583337 CA8283774	1136	K>N		No	ClinGen ExAC gnomAD
CA8283773 rs760995859	1137	Y>C		No	ClinGen ExAC gnomAD
rs760995859 CA286928612	1137	Y>S		No	ClinGen ExAC gnomAD
rs767977011 CA8283771	1138	H>Q		No	ClinGen ExAC TOPMed gnomAD
rs932284495 CA286928608	1138	H>R		No	ClinGen TOPMed gnomAD
rs1480490131 CA397644489	1139	G>E		No	ClinGen gnomAD
CA8283770 rs759649141	1139	G>R		No	ClinGen ExAC gnomAD
rs1213527968 CA397644458	1141	K>R		No	ClinGen gnomAD
TCGA novel	1142	A>missing	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA397644427 rs1214452958	1143	L>P		No	ClinGen TOPMed
rs1345255708 CA397644422	1144	K>Q		No	ClinGen gnomAD
CA8283768 rs771077108	1144	K>R		No	ClinGen ExAC TOPMed gnomAD
CA397644373 rs1198354859	1147	L>F		No	ClinGen TOPMed
CA286928577 rs867497496	1148	S>G		No	ClinGen TOPMed gnomAD
CA397644246 rs771677618	1150	H>Q		No	ClinGen ExAC TOPMed gnomAD
rs745438399 CA397644244	1151	L>F		No	ClinGen ExAC gnomAD
rs745438399 CA8283740	1151	L>V		No	ClinGen ExAC gnomAD
rs1476631310 CA397644239	1152	V>I		No	ClinGen TOPMed gnomAD
CA397644229 rs1282446079	1153	A>V		No	ClinGen TOPMed gnomAD
CA397644228 rs1395297207	1154	R>G		No	ClinGen TOPMed
rs1567576515 CA397644225	1154	R>Q		No	ClinGen Ensembl
rs1191262302 CA397644212 CA397644211	1156	Y>*		No	ClinGen TOPMed gnomAD
CA397644214 rs1597596511	1156	Y>C		No	ClinGen Ensembl
CA8283737 rs748480811	1156	Y>H		No	ClinGen ExAC gnomAD
CA8283736 rs781443977	1157	E>A		No	ClinGen ExAC gnomAD
CA397644209 rs1467952483	1157	E>Q		No	ClinGen gnomAD
CA397644190 rs1197325911	1159	K>I		No	ClinGen gnomAD
rs752043044 CA8283733	1160	A>D		No	ClinGen ExAC TOPMed gnomAD
rs1367372865 CA397644187	1160	A>T		No	ClinGen TOPMed
rs752043044 CA397644183	1160	A>V		No	ClinGen ExAC TOPMed gnomAD
rs1315727526 CA397644182	1161	E>Q		No	ClinGen TOPMed
CA8283731 rs758465453	1163	R>W		No	ClinGen ExAC gnomAD
rs765438903 CA397644158	1164	S>L		No	ClinGen ExAC gnomAD
CA8283729 rs765438903	1164	S>W		No	ClinGen ExAC gnomAD
rs1331028738 CA397644152	1165	A>V		No	ClinGen gnomAD
CA8283728 rs761944297	1166	L>P		No	ClinGen ExAC gnomAD
TCGA novel	1167	Q>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1266951736 CA397644136	1168	H>P		No	ClinGen TOPMed
rs763817167 CA8283726 CA397644133	1168	H>Q		No	ClinGen ExAC TOPMed gnomAD
CA397644131 rs1394786708	1169	E>Q		No	ClinGen TOPMed gnomAD
rs1434926907 CA397644119	1170	K>R		No	ClinGen TOPMed gnomAD
CA397644106 rs1567576329	1172	G>D		No	ClinGen Ensembl
rs760595481 CA8283725	1172	G>S		No	ClinGen ExAC TOPMed gnomAD
CA286928270 rs867860726	1176	Y>C		No	ClinGen TOPMed gnomAD
rs745317446 CA8283722	1178	T>S		No	ClinGen ExAC gnomAD
CA397644058 rs1211389990	1179	Q>R		No	ClinGen gnomAD
CA397644042 rs1345467402	1180	L>V		No	ClinGen gnomAD
rs1227693139 CA397644034	1181	G>D		No	ClinGen TOPMed gnomAD
CA397644025 rs1387797753	1182	E>D		No	ClinGen TOPMed gnomAD
CA397644031 rs1398515136	1182	E>K		No	ClinGen TOPMed gnomAD
CA397644030 rs1398515136	1182	E>Q		No	ClinGen TOPMed gnomAD
CA8283570 rs751425362	1183	D>E		No	ClinGen ExAC TOPMed gnomAD
CA397644022 rs201361018	1183	D>Y		No	ClinGen ESP ExAC TOPMed gnomAD
CA286927600 rs918014599	1184	H>Y		No	ClinGen TOPMed gnomAD
CA286927549 rs940529549 CA397643996	1186	K>N		No	ClinGen TOPMed gnomAD
CA397643998 rs1210848161	1186	K>R		No	ClinGen TOPMed
CA286927542 rs907749640	1188	K>E		No	ClinGen TOPMed
rs1242981726 CA397643984	1188	K>N		No	ClinGen gnomAD
CA397643981 rs1218024323	1189	E>K		No	ClinGen gnomAD
rs772788453 CA8283567	1190	S>G		No	ClinGen ExAC gnomAD
rs1337349944 CA397643956	1192	E>D		No	ClinGen gnomAD
CA397643961 rs769367557	1192	E>K		No	ClinGen ExAC TOPMed gnomAD
CA8283566 rs769367557	1192	E>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA397643928 rs775782224	1196	C>F		No	ClinGen ExAC gnomAD
rs775782224 CA397643929	1196	C>S		No	ClinGen ExAC gnomAD
rs775782224 CA8283564	1196	C>Y		No	ClinGen ExAC gnomAD
rs970707683 CA286927520	1199	Q>*		No	ClinGen Ensembl
CA397643908 rs1271626059	1199	Q>H		No	ClinGen gnomAD
rs1427968557 CA397643897	1201	A>S		No	ClinGen gnomAD
rs1363834902 CA397643894	1201	A>V		No	ClinGen gnomAD
rs774707686 CA8283561	1202	V>M		No	ClinGen ExAC gnomAD
CA397643888 rs1392253691	1203	A>T		No	ClinGen gnomAD
CA397643858 rs1420423162	1207	T>N		No	ClinGen gnomAD
CA397643854 rs1247520080	1208	M>T		No	ClinGen gnomAD
CA8283560 rs771482929	1208	M>V		No	ClinGen ExAC gnomAD
CA397643848 rs1194404298	1209	N>D		No	ClinGen gnomAD
CA397643846 rs1470194636	1209	N>I		No	ClinGen gnomAD
rs749262253 CA8283559	1209	N>K		No	ClinGen ExAC gnomAD
rs778032717 COSM1741998 CA8283558 COSM1741999	1211	I>M	urinary_tract [Cosmic]	No	ClinGen cosmic curated ExAC gnomAD
rs958755579 CA286927493	1213	R>C		No	ClinGen TOPMed gnomAD
CA397643818 rs979281262	1213	R>H		No	ClinGen TOPMed gnomAD
CA286927489 rs979281262	1213	R>L		No	ClinGen TOPMed gnomAD
rs1363764552 CA397643815	1214	N>D		No	ClinGen gnomAD
rs553096601 CA8283557	1214	N>S		No	ClinGen 1000Genomes ExAC gnomAD
CA286927463 rs966636440	1215	G>D		No	ClinGen TOPMed
rs781609599 CA8283555	1215	G>S		No	ClinGen ExAC TOPMed gnomAD
CA397643801 rs1442583806	1216	S>C		No	ClinGen gnomAD
rs1442583806 CA397643802	1216	S>Y		No	ClinGen gnomAD
CA8283553 rs751424895	1217	S>R		No	ClinGen ExAC gnomAD
CA8283552 rs766167419	1218	A>S		No	ClinGen ExAC TOPMed gnomAD
rs766167419 CA286927441	1218	A>T		No	ClinGen ExAC TOPMed gnomAD
CA286927429 rs372964732	1218	A>V		No	ClinGen ESP TOPMed gnomAD
CA286927394 rs903344334	1219	N>H		No	ClinGen Ensembl
CA286927390 rs1020492382	1220	I>V		No	ClinGen Ensembl
rs1253217083 CA397643766	1222	P>L		No	ClinGen TOPMed
CA8283549 rs370083702	1222	P>S		No	ClinGen ESP ExAC TOPMed gnomAD
CA8283548 rs761360860	1223	L>F		No	ClinGen ExAC gnomAD
CA397643761 rs1484318439	1223	L>R		No	ClinGen TOPMed
CA8283547 rs776234896	1224	K>R		No	ClinGen ExAC gnomAD
rs1419064527 CA397643740	1225	F>L		No	ClinGen gnomAD
CA286927197 rs886695032	1225	F>L		No	ClinGen TOPMed
CA8283502 rs767138415	1226	T>K		No	ClinGen ExAC gnomAD
rs767138415 CA8283503	1226	T>M		No	ClinGen ExAC gnomAD
rs1255129687 CA397643730	1227	A>T		No	ClinGen gnomAD
rs776806820 CA8283498	1228	P>S		No	ClinGen ExAC gnomAD
CA8283497 rs776806820	1228	P>T		No	ClinGen ExAC gnomAD
CA397643716 rs768761272	1229	S>I		No	ClinGen ExAC gnomAD
CA8283496 rs768761272	1229	S>T		No	ClinGen ExAC gnomAD
CA8283495 rs536918371	1230	M>V		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs548922441 CA397643705	1231	A>P		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs548922441 CA8283494	1231	A>T		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA397643697 rs1312298241	1232	S>N		No	ClinGen gnomAD
rs1338922200 CA397643700	1232	S>R		No	ClinGen gnomAD
rs1382785933 CA397643694	1232	S>R		No	ClinGen gnomAD
TCGA novel	1234	L>W	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA8283492 rs745595525	1235	E>D		No	ClinGen ExAC TOPMed gnomAD
rs770805106 CA8283491	1236	Q>H		No	ClinGen ExAC gnomAD
CA286927155 COSM178385 rs958704192	1239	V>I	Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated NCI-TCGA gnomAD
CA8283487 rs778345831	1240	I>L		No	ClinGen ExAC TOPMed gnomAD
rs778345831 CA8283488	1240	I>V		No	ClinGen ExAC TOPMed gnomAD
rs1174402035 CA397643630	1242	G>D		No	ClinGen TOPMed
CA8283484 rs754686354	1244	L>F		No	ClinGen ExAC TOPMed gnomAD
CA397643606 rs1597593197	1246	I>F		No	ClinGen Ensembl
rs1597593197 CA397643608	1246	I>L		No	ClinGen Ensembl
CA286927126 rs925387768	1246	I>T		No	ClinGen TOPMed gnomAD
CA397643598 rs1187440059	1247	P>L		No	ClinGen TOPMed gnomAD
rs765721468 CA8283482	1248	L>F		No	ClinGen ExAC gnomAD
rs765721468 CA397643595	1248	L>V		No	ClinGen ExAC gnomAD
CA397643586 rs1275045261	1249	S>I	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA397643566 rs1486492354	1250	Q>R		No	ClinGen TOPMed
CA8283441 rs749600265	1252	D>G		No	ClinGen ExAC gnomAD
TCGA novel	1252	D>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	1252	D>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA8283439 rs549649510	1253	L>P		No	ClinGen 1000Genomes ExAC gnomAD
rs1241194041 CA397643532	1255	N>T		No	ClinGen gnomAD
CA397643525 rs1230558068	1256	L>P		No	ClinGen gnomAD
rs753112710 CA8283438	1257	K>E		No	ClinGen ExAC TOPMed gnomAD
rs1287267400 CA397643510	1258	A>V		No	ClinGen gnomAD
rs755035595 CA8283436	1259	E>G		No	ClinGen ExAC gnomAD
CA8283437 rs768077476	1259	E>K		No	ClinGen ExAC gnomAD
rs915508654 CA286926134	1260	V>M		No	ClinGen TOPMed
rs766517607 CA8283433	1261	A>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA397643492 rs1470713258	1262	R>Q	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
CA286926131 rs1039086991	1262	R>W		No	ClinGen TOPMed
CA397643471 rs764923110 CA8283430	1265	Q>H		No	ClinGen ExAC TOPMed gnomAD
CA8283431 rs750187614	1265	Q>R		No	ClinGen ExAC gnomAD
rs1358307209 CA397643469	1266	L>V		No	ClinGen TOPMed
rs761710871 CA8283429	1268	E>G		No	ClinGen ExAC TOPMed gnomAD
CA397643447 rs1239497692	1269	A>S		No	ClinGen gnomAD
rs1239497692 CA397643449	1269	A>T		No	ClinGen gnomAD
rs776708713 CA8283428	1269	A>V		No	ClinGen ExAC gnomAD
rs768772679 CA8283427	1270	S>G		No	ClinGen ExAC gnomAD
rs760207056 CA8283426	1270	S>I		No	ClinGen ExAC TOPMed gnomAD
rs760207056 CA286926096	1270	S>N		No	ClinGen ExAC TOPMed gnomAD
rs1211149578 CA397643437	1271	R>K		No	ClinGen gnomAD
rs771715913 CA8283425	1273	R>G		No	ClinGen ExAC gnomAD
rs771715913 CA8283424	1273	R>W		No	ClinGen ExAC gnomAD
CA397643416 rs1283935673	1274	D>G		No	ClinGen TOPMed
CA8283422 rs745486555	1276	A>V		No	ClinGen ExAC gnomAD
CA8283418 rs531117604	1279	P>L		No	ClinGen 1000Genomes ExAC gnomAD
CA8283419 rs531117604	1279	P>R		No	ClinGen 1000Genomes ExAC gnomAD
CA397643381 rs1326532852	1279	P>S		No	ClinGen gnomAD
rs751594901 CA8283416	1280	M>T		No	ClinGen ExAC gnomAD
rs929544170 CA286926058	1281	A>G		No	ClinGen TOPMed gnomAD
CA286926054 rs929544170	1281	A>V		No	ClinGen TOPMed gnomAD
CA8283415 rs780134393	1282	T>I		No	ClinGen ExAC gnomAD
rs765565801 CA8283412	1283	E>K		No	ClinGen ExAC gnomAD
rs753701529 CA8283410	1284	P>S		No	ClinGen ExAC gnomAD
rs760726368 CA8283408	1285	A>T		No	ClinGen ExAC gnomAD
rs775616460 CA8283407	1285	A>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs771451632 CA8283406	1286	P>L		No	ClinGen ExAC gnomAD
CA8283405 rs528743275	1287	A>P		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA8283404 rs528743275	1287	A>T		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
COSM3819072 CA397643338 rs1287260628 COSM3819071	1287	A>V	Variant assessed as Somatic; 0.0 impact. breast [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated NCI-TCGA gnomAD
CA286926012 rs1005396936	1288	G>E		No	ClinGen TOPMed gnomAD
CA397643331 rs1432341490	1289	A>G		No	ClinGen gnomAD
rs959037279 CA286926006	1289	A>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
rs959037279 CA286926010	1289	A>T		No	ClinGen TOPMed gnomAD
CA397643323 rs1161019212	1290	P>L		No	ClinGen TOPMed
rs1326512987 CA397643328	1290	P>T		No	ClinGen gnomAD
CA8283400 rs559628095	1291	G>E	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
CA8283401 rs559628095	1291	G>V		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs529291178 CA8283398	1292	D>N		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA286925979 rs952500727	1293	L>M		No	ClinGen TOPMed
rs1403150077 CA397643310	1293	L>P		No	ClinGen TOPMed
rs1391092753 CA397643307	1294	G>S		No	ClinGen gnomAD
CA397643302 rs1170554071	1294	G>V		No	ClinGen TOPMed gnomAD
CA397643296 rs1447749888	1295	S>F	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
CA397643286 rs750576929	1297	P>A		No	ClinGen ExAC gnomAD
CA397643284 rs1025464727	1297	P>L		No	ClinGen TOPMed gnomAD
rs1025464727 CA286925976	1297	P>R		No	ClinGen TOPMed gnomAD
rs750576929 CA8283396	1297	P>S		No	ClinGen ExAC gnomAD
CA8283393 rs753646363	1299	A>D		No	ClinGen ExAC gnomAD
CA397643275 rs1221343818	1299	A>S		No	ClinGen gnomAD
CA397643268 rs1288477703	1300	A>D		No	ClinGen TOPMed gnomAD
rs1490708180 CA397643261	1301	K>M		No	ClinGen TOPMed
CA397643257 rs1225470795	1302	D>H		No	ClinGen gnomAD
CA8283388 rs767546776	1303	P>L		No	ClinGen ExAC TOPMed gnomAD
rs752675058 CA397643249	1303	P>S		No	ClinGen ExAC TOPMed gnomAD
CA8283389 rs752675058	1303	P>T		No	ClinGen ExAC TOPMed gnomAD
CA8283387 rs370836405	1305	P>S		No	ClinGen ESP ExAC gnomAD
CA397643234 rs1442733255	1306	S>G		No	ClinGen gnomAD
CA8283384 rs772903126	1307	V>L		No	ClinGen ExAC TOPMed gnomAD
CA8283383 rs772903126	1307	V>M		No	ClinGen ExAC TOPMed gnomAD
CA8283381 rs200380079	1308	Q>H		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1333465026 CA397643212	1309	G>E		No	ClinGen Ensembl

No associated diseases with O75153

3 regional properties for O75153

Type	Name	Position	InterPro Accession
domain	CLU domain	335 - 577	IPR025697
domain	Clustered mitochondria protein, N-terminal	66 - 139	IPR028275
domain	CLU central domain	767 - 948	IPR033646

Functions

		Description
EC Number
Subcellular Localization	Cytoplasm Cytoplasmic granule	A fraction colocalizes with tyrosinated tubulin and can be detected close to mitochondria
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

1 GO annotations of cellular component

Name	Definition
cytoplasm	The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name	Definition
mRNA binding	Binding to messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.

2 GO annotations of biological process

Name	Definition
intracellular distribution of mitochondria	Any process that establishes the spatial arrangement of mitochondria within the cell.
mitochondrion organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components.

No homologous proteins in AiPD

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
No homologous proteins

10	20	30	40	50	60
MLLNGDCPES	LKKEAAAAEP	PRENGLDEAG	PGDETTGQEV	IVIQDTGFSV	KILAPGIEPF
70	80	90	100	110	120
SLQVSPQEMV	QEIHQVLMDR	EDTCHRTCFS	LHLDGNVLDH	FSELRSVEGL	QEGSVLRVVE
130	140	150	160	170	180
EPYTVREARI	HVRHVRDLLK	SLDPSDAFNG	VDCNSLSFLS	VFTDGDLGDS	GKRKKGLEMD
190	200	210	220	230	240
PIDCTPPEYI	LPGSRERPLC	PLQPQNRDWK	PLQCLKVLTM	SGWNPPPGNR	KMHGDLMYLF
250	260	270	280	290	300
VITAEDRQVS	ITASTRGFYL	NQSTAYHFNP	KPASPRFLSH	SLVELLNQIS	PTFKKNFAVL
310	320	330	340	350	360
QKKRVQRHPF	ERIATPFQVY	SWTAPQAEHA	MDCVRAEDAY	TSRLGYEEHI	PGQTRDWNEE
370	380	390	400	410	420
LQTTRELPRK	NLPERLLRER	AIFKVHSDFT	AAATRGAMAV	IDGNVMAINP	SEETKMQMFI
430	440	450	460	470	480
WNNIFFSLGF	DVRDHYKDFG	GDVAAYVAPT	NDLNGVRTYN	AVDVEGLYTL	GTVVVDYRGY
490	500	510	520	530	540
RVTAQSIIPG	ILERDQEQSV	IYGSIDFGKT	VVSHPRYLEL	LERTSRPLKI	LRHQVLNDRD
550	560	570	580	590	600
EEVELCSSVE	CKGIIGNDGR	HYILDLLRTF	PPDLNFLPVP	GEELPEECAR	AGFPRAHRHK
610	620	630	640	650	660
LCCLRQELVD	AFVEHRYLLF	MKLAALQLMQ	QNASQLETPS	SLENGGPSSL	ESKSEDPPGQ
670	680	690	700	710	720
EAGSEEEGSS	ASGLAKVKEL	AETIAADDGT	DPRSREVIRN	ACKAVGSISS	TAFDIRFNPD
730	740	750	760	770	780
IFSPGVRFPE	SCQDEVRDQK	QLLKDAAAFL	LSCQIPGLVK	DCMEHAVLPV	DGATLAEVMR
790	800	810	820	830	840
QRGINMRYLG	KVLELVLRSP	ARHQLDHVFK	IGIGELITRS	AKHIFKTYLQ	GVELSGLSAA
850	860	870	880	890	900
ISHFLNCFLS	SYPNPVAHLP	ADELVSKKRN	KRRKNRPPGA	ADNTAWAVMT	PQELWKNICQ
910	920	930	940	950	960
EAKNYFDFDL	ECETVDQAVE	TYGLQKITLL	REISLKTGIQ	VLLKEYSFDS	RHKPAFTEED
970	980	990	1000	1010	1020
VLNIFPVVKH	VNPKASDAFH	FFQSGQAKVQ	QGFLKEGCEL	INEALNLFNN	VYGAMHVETC
1030	1040	1050	1060	1070	1080
ACLRLLARLH	YIMGDYAEAL	SNQQKAVLMS	ERVMGTEHPN	TIQEYMHLAL	YCFASSQLST
1090	1100	1110	1120	1130	1140
ALSLLYRARY	LMLLVFGEDH	PEMALLDNNI	GLVLHGVMEY	DLSLRFLENA	LAVSTKYHGP
1150	1160	1170	1180	1190	1200
KALKVALSHH	LVARVYESKA	EFRSALQHEK	EGYTIYKTQL	GEDHEKTKES	SEYLKCLTQQ
1210	1220	1230	1240	1250	1260
AVALQRTMNE	IYRNGSSANI	PPLKFTAPSM	ASVLEQLNVI	NGILFIPLSQ	KDLENLKAEV
1270	1280	1290	1300
ARRHQLQEAS	RNRDRAEEPM	ATEPAPAGAP	GDLGSQPPAA	KDPSPSVQG