O74969

PR
Gene name
ght2 (SPBC4B4.08)
Protein name
High-affinity glucose transporter ght2
Names
Hexose transporter 2
Species
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
KEGG Pathway
spo:SPBC4B4.08
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

455-531 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O74969

Entry ID Method Resolution Chain Position Source
AF-O74969-F1 Predicted AlphaFoldDB

No variants for O74969

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O74969

No associated diseases with O74969

5 regional properties for O74969

Type Name Position InterPro Accession
domain Alpha-D-phosphohexomutase, C-terminal 405 - 470 IPR005843
domain Alpha-D-phosphohexomutase, alpha/beta/alpha domain I 32 - 160 IPR005844
domain Alpha-D-phosphohexomutase, alpha/beta/alpha domain II 188 - 284 IPR005845
domain Alpha-D-phosphohexomutase, alpha/beta/alpha domain III 288 - 401 IPR005846
conserved_site Alpha-D-phosphohexomutase, conserved site 123 - 132 IPR016066

Functions

Description
EC Number
Subcellular Localization
  • Membrane; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
integral component of plasma membrane The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
carbohydrate:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: carbohydrate(out) + H+(out) = carbohydrate(in) + H+(in).
galactose transmembrane transporter activity Enables the transfer of galactose from one side of a membrane to the other. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose.

2 GO annotations of biological process

Name Definition
carbohydrate transport The directed movement of carbohydrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbohydrates are a group of organic compounds based of the general formula Cx(H2O)y.
galactose import across plasma membrane The directed movement of galactose from outside of a cell, across the plasma membrane and into the cytosol.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGFKRGKNFT LVMLIFVSMA GWMFGADTGS IGGVTSMRDF RERYADRYDP ITDQYSLSSA
70 80 90 100 110 120
RQGLLTGMVN VGSLFGCIIS SPIADRFGKR LSIIGFCAVY IIGIIVQVTA VPSWVQIMVA
130 140 150 160 170 180
KIWTGIGIGA LSVLAPGYQS ETAPPSIRGT VVVTYQLFVT GGIFIAACIN MGTHKLHKTA
190 200 210 220 230 240
QWRVSIGINL LWGIITMIGI LFLPESPRYL IQVGKDEEAV RVLSESAELF PDSEEVQNEY
250 260 270 280 290 300
HRLKSSIDEE FAGGPCSWAS IFGKDIRYRT FLGMFVMSLQ QLTGNNYFFY YGFSVMQGAG
310 320 330 340 350 360
INSPYLSAMI LDAVNFGCTF GGMYVLERFG RRNPLIIGGI WQSICFFIYS AVGSRALYHK
370 380 390 400 410 420
NGTSNTRAGA VMIVMACLFI FGFAQTWAPA AYVIVGESYP VRYRSKCAAV ATASNWLWNF
430 440 450 460 470 480
LISFFTPFIQ ASIGFKYGYV FASCNLTGAI VIFLFAKETK GLTLEEINEL YMSVIKPWES
490 500 510 520 530
GNFKLNYSEQ KKVEKEKSRK GGARGESVEY VERASNTDSS PQYSSHEEDY A