O74923

PR
Gene name
SPCC757.13
Protein name
Uncharacterized transporter C757.13
Names
Species
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
KEGG Pathway
spo:SPCC757.13
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-85 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O74923

Entry ID Method Resolution Chain Position Source
AF-O74923-F1 Predicted AlphaFoldDB

No variants for O74923

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O74923

No associated diseases with O74923

1 regional properties for O74923

Type Name Position InterPro Accession
domain Major facilitator superfamily domain 77 - 486 IPR020846

Functions

Description
EC Number
Subcellular Localization
  • Endoplasmic reticulum
  • Membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
endoplasmic reticulum The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
intrinsic component of membrane The component of a membrane consisting of the gene products having some covalently attached portion, for example part of a peptide sequence or some other covalently attached group such as a GPI anchor, which spans or is embedded in one or both leaflets of the membrane.

2 GO annotations of molecular function

Name Definition
dipeptide transmembrane transporter activity Enables the transfer of a dipeptide from one side of a membrane to the other. A dipeptide is a combination of two amino acids linked together by a peptide (-CO-NH-) bond.
transmembrane transporter activity Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other.

2 GO annotations of biological process

Name Definition
dipeptide transmembrane transport The directed movement of a dipeptide across a membrane by means of some agent such as a transporter or pore. A dipeptide is a combination of two amino acids linked together by a peptide (-CO-NH-) bond.
ion transmembrane transport A process in which an ion is transported across a membrane.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSSITSRVSS RSSHELTEKK SGVTNDFKNS FEVGEVKRLP DAEGTADAVA QELLADDDFT
70 80 90 100 110 120
YTAKEARRVL WKIDLVMMPV MCITYMIQYL DKTALSYAAL YGMKTDTHID GHTYSSMTTL
130 140 150 160 170 180
FYAGYLVAQY PAAILMQKCR LSYFIFCNVF LWSAMVCLMA ACRNGPSLLG LRFLAGIFEA
190 200 210 220 230 240
SITPAFINIT AMWYRREEQP MRTLCWYAFN GIAQIIGSIL SYGLGHIHGK VASWRYVFIV
250 260 270 280 290 300
IGLMSLGWGV VFVFIPSNPS KARFLSSREK RIALERVRDN RTGLENKQFK WKHAYEAFLD
310 320 330 340 350 360
PQVIMITLFT GVCMITNGIG VFSTLIIKGL GYNELHSAVL NMPLGAIEVA AMFISGVLCK
370 380 390 400 410 420
VFKNGRLLIG VFMNCLTLAG CLMIWKIPDS NPYGRLVGVW FTMWVPASSA LLLSLISSNV
430 440 450 460 470 480
AGYTKKTVTS ATVFVFYSVG NIVSPQLFKS GQTPEYIEGI QAMIVSLCII IAIAFVLTGY
490 500 510 520
YIYENKRRDR LLAEDPSLGE SIKNEEFMDL TDRQQPKFRY RW