O74879
Gene name |
enp2 (SPCC330.09) |
Protein name |
Ribosome biogenesis protein enp2 homolog |
Names |
|
Species |
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
KEGG Pathway |
spo:SPCC330.09 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O74879
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O74879-F1 | Predicted | AlphaFoldDB |
No variants for O74879
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O74879 | |||||
No associated diseases with O74879
3 regional properties for O74879
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| repeat | WD40 repeat | 173 - 212 | IPR001680-1 |
| repeat | WD40 repeat | 226 - 265 | IPR001680-2 |
| domain | NUC153 | 491 - 518 | IPR012580 |
5 GO annotations of cellular component
| Name | Definition |
|---|---|
| 90S preribosome | A large ribonucleoprotein complex considered to be the earliest preribosomal complex. In S. cerevisiae, it has a size of 90S and consists of the 35S pre-rRNA, early-associating ribosomal proteins most of which are part of the small ribosomal subunit, the U3 snoRNA and associated proteins. |
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| nucleolus | A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| small-subunit processome | A large ribonucleoprotein complex that is an early preribosomal complex. In S. cerevisiae, it has a size of 80S and consists of the 35S pre-rRNA, early-associating ribosomal proteins most of which are part of the small ribosomal subunit, the U3 snoRNA and associated proteins. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and the Large Subunit (LSU) in that order from 5' to 3' along the primary transcript. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSLKVQNPNN | VRVYTVSGEG | VTQRLPNWIS | KRKLKKDYAL | SHRIELLQDF | EYPEASNRIK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| CTRDGKYAMA | TGVYKPHIKV | FDFAEMSLKF | ERHTDAENVQ | FEILSDDWTK | SVHLQTDRTV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DFHSQGGIHY | STRIPKYGRD | LKYHYPNCDL | YLAAAGDEVY | RLNLEQGRFL | NPLKIESAQI |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DSPTGGVNVI | DINPMHQLLA | FGTDAGSVEF | WDPRDRSRVG | ILEIPSTVPS | TPYSDNSRSV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| TALKYRNDGL | NVAIGLSDGA | TLLYDLRSSS | PYMSKDQGYS | MPIKSLHWMD | SALDGTARVL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| SADSKIIKIW | EKDTGKPFSS | IEPTVELNDV | CPIEGTGLIL | TANEGSPMHA | FYIPSLNPAP |
| 370 | 380 | 390 | 400 | 410 | 420 |
| RWCSFLDNIT | EEMEENPAPT | IYDDYKFVTK | KELLNLGLDH | LVGTGVIRAY | MHGFFIDNNL |
| 430 | 440 | 450 | 460 | 470 | 480 |
| YEKARLIANP | FSYEEHRQKI | VKERLEKQRA | SKIRSQNRPK | VNAGLASRLS | YQENKLRKKT |
| 490 | 500 | 510 | 520 | 530 | 540 |
| GVTDGPSILE | DERFKNVFTD | KEFEVDEDTL | EYKQLHPSRS | EARGLTAAEE | SEEEKEHTKG |
| 550 | 560 | 570 | 580 | 590 | 600 |
| IKFSSDEESL | SDMEEENETF | DALVDRRKTE | QQVSNEKTPQ | ETIRSTPSGM | EMTFKVEKKK |
| 610 | 620 | 630 | |||
| KSKPVNRDED | STSGKKKQVT | QGRRSASKNV | FRNM |