O74823
Gene name |
SPBC337.12 |
Protein name |
Zinc finger CCCH domain-containing protein C337.12 |
Names |
|
Species |
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
KEGG Pathway |
spo:SPBC337.12 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O74823
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O74823-F1 | Predicted | AlphaFoldDB |
No variants for O74823
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O74823 | |||||
No associated diseases with O74823
4 regional properties for O74823
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Zinc finger, CCCH-type | 202 - 229 | IPR000571-1 |
| domain | Zinc finger, CCCH-type | 229 - 256 | IPR000571-2 |
| domain | Zinc finger, CCCH-type | 257 - 283 | IPR000571-3 |
| domain | Zinc finger, CCCH-type | 284 - 312 | IPR000571-4 |
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| chromatin | The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome. |
| MTREC complex | Protein complex formed by an RNA binding protein Red1, an RNA helicase Mtl1, Red5, Rmn1, Iss10/Pir1, and Ars2/Pir2. This complex is required for the recruitment of the nuclear exosome to Mmi1 nuclear focus. It is likely related to the human CBCN complex. This complex is also known as RNA silencing (NURS) complex. |
| nuclear body | Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| metal ion binding | Binding to a metal ion. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts | The chemical reactions and pathways resulting in the selective degradation of meiosis-specific transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MNEQQLLENI | ASLAGAINQY | KNEKEPTQVL | DAAKANKNTR | SYPYSVSRNY | SFILNKSNRS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KSTAASPPYV | IPSTSSNADD | ANKEPEKQST | SDYVSRKNRH | MQLIKKNILE | HDLQARKANL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ESYRAKLEKE | YKTLAENKIQ | QRLSDGTKQL | VTIDGLQYIT | GVSDTKWLEF | VSAKGQCPKY |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LYWNNKSYLL | KKKRFLKEVG | NSPSAVYCRY | YNANGICGKG | AACRFVHEPT | RKTICPKFLN |
| 250 | 260 | 270 | 280 | 290 | 300 |
| GRCNKAEDCN | LSHELDPRRI | PACRYFLLGK | CNNPNCRYVH | IHYSENAPIC | FEFAKYGFCE |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LGTSCKNQHI | LQCTDYAMFG | SCNNPQCSLY | HGAVSADVPE | QTEAPISKTA | GSINPEDSGS |
| 370 | |||||
| EIGSNSLESN | LDFISV |