O74638

PR
Gene name
URA7 (FGRAMPH1_01T25925, FGRRES_07897_M, FGSG_07897)
Protein name
CTP synthase
Names
CTP synthetase, UTP--ammonia ligase
Species
Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1) (Wheat head blight fungus) (Fusarium graminearum)
KEGG Pathway
fgr:FGSG_07897
EC number
6.3.4.2: Other carbon--nitrogen ligases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

309-382 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O74638

Entry ID Method Resolution Chain Position Source
AF-O74638-F1 Predicted AlphaFoldDB

No variants for O74638

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O74638

No associated diseases with O74638

3 regional properties for O74638

Type Name Position InterPro Accession
domain CTP synthase, N-terminal 2 - 270 IPR017456
domain Glutamine amidotransferase 314 - 546 IPR017926
domain CTP synthase GATase domain 303 - 550 IPR033828

Functions

Description
EC Number 6.3.4.2 Other carbon--nitrogen ligases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
CTP synthase activity Catalysis of the reaction: ATP + UTP + glutamine + H20= ADP + phosphate + CTP + glutamate.

2 GO annotations of biological process

Name Definition
'de novo' CTP biosynthetic process The chemical reactions and pathways resulting in the formation of cytidine 5'-triphosphate (CTP) from simpler components.
glutamine metabolic process The chemical reactions and pathways involving glutamine, 2-amino-4-carbamoylbutanoic acid.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKVVLVSGGV ISGVGKGIIA SSAGLLLKTL GLRVTAIKTD PYINTDAGLL NPLEHGECFV
70 80 90 100 110 120
LDDGGETDLD LGNYERYLGI QLSRDSNITT GKIYKQVIEK ERRGDYLGKT VQVVPHITDA
130 140 150 160 170 180
IQDWIERVAK IPVDASGEAP DVCIIELGGT IGDLESGPFV EALSQLRHRL GRDNFLSISV
190 200 210 220 230 240
SYVPIINGEE KTKPTQHAIR QVRSAGLIPD VIACRCEREL DQATITKIAR SCQVEDEQVI
250 260 270 280 290 300
GVRNMDTIYQ VPLLLEQEGL LKLLQKGLAL DKCQVTPPMA QKGQALWDLW KKTVVPDRHL
310 320 330 340 350 360
EPVNIILVGK YVSLDDSYLS VHKALEHSAM RCNRKLNLVS VDSEHLEPEM QEKDPRKFHE
370 380 390 400 410 420
AWAHVVRAQG IIVPGGFGTR GIQGMVDVAK WARERKLPYL GICLGMQTAV IEYARNVMGL
430 440 450 460 470 480
KGATSEEFSA TAEHRVVIFM PEGSKEQMGG TMRLGSRTSH FKPGTEWSKL RGLYGGVDVV
490 500 510 520 530 540
EERHRHRYEV NPDYIEDLEK AGLSLTSMDD QGVRVETIEL KDHPFFVGLQ AHPEYKSKTL
550 560 570
APAPSLLGLV AASSGCLDEI IEAAHKKQSS SNGVSDVTNF