Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O74490
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O74490-F1 | Predicted | AlphaFoldDB |
No variants for O74490
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O74490 | |||||
No associated diseases with O74490
No regional properties for O74490
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for O74490 | |||
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| endosome | A vacuole to which materials ingested by endocytosis are delivered. |
| Golgi apparatus | A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| protein localization | Any process in which a protein is transported to, or maintained in, a specific location. |
| protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway | The process of directing proteins towards the vacuole that contributes to protein catabolism via the multivesicular body (MVB) pathway. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSRLQIQLKL | AASRIEILRQ | KEEALAKQAR | RNVALGLKSY | SPALAKARIE | PLIMQDIYIE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LLELLQVDVE | ILANRCVVLE | KRAFNDSMSF | KSSLYHVMAA | APQLQIKELR | FVHDFLVKLY |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GKEFARLSDP | DLATNDTAFY | QLLYPPIPKD | ELVEAYRKEL | IRTYFPNDYP | KEANKDIPSS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| AEADTMLNLE | SSENREQPTS | LKEENTQEDD | EKVNGNLANI | SKRAEPQNNG | STNASSLQSS |
| 250 | 260 | 270 | |||
| NYLPTNPTLT | HSNKAPSFEE | LAARLDRLKH | L |