O74446
Gene name |
sif2 (SPCC16C4.01, SPCC5E4.09) |
Protein name |
Sad1-interacting factor 2 |
Names |
Sporulation protein sif2 |
Species |
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
KEGG Pathway |
spo:SPCC16C4.01 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O74446
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O74446-F1 | Predicted | AlphaFoldDB |
No variants for O74446
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O74446 | |||||
No associated diseases with O74446
11 regional properties for O74446
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | RNA polymerase sigma-70 | 178 - 191 | IPR000943-1 |
| domain | RNA polymerase sigma-70 | 202 - 210 | IPR000943-2 |
| domain | RNA polymerase sigma-70 | 326 - 338 | IPR000943-3 |
| domain | RNA polymerase sigma-70 | 347 - 373 | IPR000943-4 |
| domain | RNA polymerase sigma factor 70, region 1.1 | 24 - 101 | IPR007127 |
| domain | RNA polymerase sigma-70 region 3 | 233 - 309 | IPR007624 |
| domain | RNA polymerase sigma-70 region 2 | 154 - 223 | IPR007627 |
| domain | RNA polymerase sigma-70 region 4 | 322 - 375 | IPR007630 |
| domain | RNA polymerase sigma-70 region 1.2 | 113 - 145 | IPR009042 |
| domain | RNA polymerase sigma factor RpoD, C-terminal | 150 - 386 | IPR012760 |
| domain | RNA polymerase sigma-70 like domain | 152 - 375 | IPR014284 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| mitochondrial matrix | The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation. |
| nuclear membrane | Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| meiotic cell cycle | Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions. |
| mitochondrial gene expression | The process in which a mitochondrial gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form. |
| sporulation resulting in formation of a cellular spore | The process in which a relatively unspecialized cell acquires the specialized features of a cellular spore, a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSNRIGPQRS | TKTAAKLRLL | PSTEEFDDFR | RQDTGREVYS | QIPQIEGSTA | KRDAEHLGKR |
| 70 | 80 | 90 | 100 | 110 | 120 |
| HREFLPRVTA | YCTCDTFRVD | LLFKFFQSRR | SSHKTRPKQF | DECIYSPYSY | NNEETTDLLP |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DTLESSRGTL | NRESSQESLQ | SIFEESGLDR | NQPLFREVFC | FTYGVVVLWG | YTIDEEHRFL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| RELGRFEIEK | LKIEDMEVEE | FNYYITTLYQ | PRIFNDFIAL | RDASNYMIRL | SISHAIAQSV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| KISLFEELVN | ETIDATKDTP | QMIAETGRVN | LKREEIMMAV | GQLFILRINI | NLQGSVLDSP |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ELMWTEPQLE | PIYTAARSYL | EINQRVALLN | QRVEVIGDLL | SMLKEQITHT | HDESLEWIVV |
| 370 | 380 | ||||
| ILMGLLVLIA | LFSIVVDWKL | FQ |