O74083
Gene name |
cpgS |
Protein name |
Cyclic 2,3-diphosphoglycerate synthetase |
Names |
cDPGS |
Species |
Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) |
KEGG Pathway |
pho:PH0150 |
EC number |
6.5.1.9: Forming phosphoric ester bonds |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O74083
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O74083-F1 | Predicted | AlphaFoldDB |
No variants for O74083
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O74083 | |||||
No associated diseases with O74083
No regional properties for O74083
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for O74083 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 6.5.1.9 | Forming phosphoric ester bonds |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| cyclic 2,3-diphosphoglycerate synthetase activity | Catalysis of the reaction: 2,3-diphosphoglycerate (DPG) + ATP = cyclic 2,3-diphosphoglycerate (cDPG) + ADP + phosphate. |
| ligase activity | Catalysis of the joining of two molecules, or two groups within a single molecule, using the energy from the hydrolysis of ATP, a similar triphosphate, or a pH gradient. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| gluconeogenesis | The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGYAMRLALI | DGEHYPDVNR | WALEKLKVDC | AVFVGGMEKI | GSIRDVERTL | SIKLYYDEDI |
| 70 | 80 | 90 | 100 | 110 | 120 |
| FKALERAIEE | NEIREVIDLS | DEPVLTPEIR | FRIASFLLKR | GITYIGADFE | FKPKEWIKID |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VPSINIIGTG | KRIGKTAIGG | FVGRTLKEEY | KVVIVTMGRG | GPESPEVIRG | DLMEITPEFL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VEVSEKGRHA | ASDHFEDALT | AGVATVGCRR | CGGGLAGFTF | LDVLQKGIEV | AKSLNPEIIV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| FEGSGASFAN | VLSEGFITVV | SALQGKEIKM | YLYPLRISLG | DLIVVTMADE | VKDPGKISSL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| IKEINPDADI | HLTRFSPRLI | GNVEGKAVVV | TTSTNSAKRV | TKELEDRGID | VVGFSGNLAN |
| 370 | 380 | 390 | 400 | 410 | 420 |
| RVKLREELKK | VSYDTLIVEL | KAGAVDVAIK | SALRSGKRIV | FLDYEPKNID | DKDLRESVKE |
| 430 | |||||
| LARRIVNDKG | HRKGR |