O73942

PR
Gene name
apeI (APE_1929.1)
Protein name
Homing endonuclease I-ApeI
Names
rRNA intron-encoded homing endonuclease 1
Species
Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)
KEGG Pathway
ape:APE_1929.1
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

169-222 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O73942

Entry ID Method Resolution Chain Position Source
AF-O73942-F1 Predicted AlphaFoldDB

No variants for O73942

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O73942

No associated diseases with O73942

1 regional properties for O73942

Type Name Position InterPro Accession
domain Homing endonuclease, LAGLIDADG 107 - 183 IPR004860

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
endonuclease activity Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks.

1 GO annotations of biological process

Name Definition
intron homing Lateral transfer of an intron to a homologous allele that lacks the intron, mediated by a site-specific endonuclease encoded within the mobile intron.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDGYALFYLV GALRDGSVYR YSRNYYVIWY SSNKDYLERV IVSKLRILGF HNVRVYQYKR
70 80 90 100 110 120
GAYRVRISSK QLFHILVNQF EHPLSTSSRK TPWPTPQRVK DGPLALQIEY VKGFVDAEGS
130 140 150 160 170 180
VIKSSKGVQV DVSQQIMEPL KFLAQVLEKV GVKVTGIYLG SDGVWRLRIA SLASLRRFAH
190 200 210 220
YIGFRHPCKS KKLNELLGRP LPGPSKLKGI GGGAPQGVEP AA