Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O73849
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O73849-F1 | Predicted | AlphaFoldDB |
No variants for O73849
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O73849 | |||||
No associated diseases with O73849
2 regional properties for O73849
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Somatotropin hormone, conserved site | 77 - 110 | IPR018116-1 |
| conserved_site | Somatotropin hormone, conserved site | 186 - 203 | IPR018116-2 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| extracellular space | That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| growth hormone receptor binding | Binding to a growth hormone receptor. |
| hormone activity | The action characteristic of a hormone, any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action. The term was originally applied to agents with a stimulatory physiological action in vertebrate animals (as opposed to a chalone, which has a depressant action). Usage is now extended to regulatory compounds in lower animals and plants, and to synthetic substances having comparable effects; all bind receptors and trigger some biological process. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MASGLCSSLG | LLLIMCLQSP | PGFSAFPQIP | LASLLNNAVI | RAQYIRQVVA | DTYRDYEQTF |
| 70 | 80 | 90 | 100 | 110 | 120 |
| IREDKRYSNK | NSYAMFCYSE | TIPAPTDKDN | THQKSDIDLL | RFSLTLIQSW | MTPVQSLNKL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| FTNQVFGNAV | YEKLRDLEEG | LYALMRELDD | GNARNYGLLT | FTYDKFDPHP | DSDDDGRIKN |
| 190 | 200 | 210 | |||
| YGLLSCFKKD | MHKVETYLKV | MKCRRFVESN | CMV |