O73615

PR
Gene name
hand1 (ehand)
Protein name
Heart- and neural crest derivatives-expressed protein 1
Names
Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1, eHAND
Species
Xenopus laevis (African clawed frog)
KEGG Pathway
xla:373663
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

23-108 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O73615

Entry ID Method Resolution Chain Position Source
AF-O73615-F1 Predicted AlphaFoldDB

No variants for O73615

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O73615

No associated diseases with O73615

3 regional properties for O73615

Type Name Position InterPro Accession
domain 3-hydroxyacyl-CoA dehydrogenase, C-terminal 189 - 284 IPR006108
domain 3-hydroxyacyl-CoA dehydrogenase, NAD binding 7 - 185 IPR006176
conserved_site 3-hydroxyacyl-CoA dehydrogenase, conserved site 185 - 210 IPR006180

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
  • Nucleus, nucleolus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.

2 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
protein dimerization activity The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNLIGSYQHH HHHMMPDPFI FSPGSRCHQE RPYFQGWVLN PGEVSPEFPA QPPYSPEYGA
70 80 90 100 110 120
VVGPSQTSGR IENLGGKLGR RKGAPPKKER RRTESINSAF AELRECIPNV PADTKLSKIK
130 140 150 160 170 180
TLRLATSYIG YLMDVLAKDS EPGGTEAFKA EIKKVDGKRR REPQPTEGYW GAAPAGEKKL
190
KGRTGWPQQV WALELNP