O71153

PR
Gene name
NS1
Protein name
Initiator protein NS1
Names
NS1, Non-structural protein 1, Non-structural protein NS1
Species
Diatraea saccharalis densovirus (DsDNV)
KEGG Pathway
vg:1449608
EC number
3.6.4.12: Acting on ATP; involved in cellular and subcellular movement
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-54 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

0 structures for O71153

Entry ID Method Resolution Chain Position Source

No variants for O71153

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O71153

No associated diseases with O71153

2 regional properties for O71153

Type Name Position InterPro Accession
domain Parvovirus non-structural protein 1, helicase domain 387 - 504 IPR001257
domain Helicase, superfamily 3, DNA virus 346 - 545 IPR014015

Functions

Description
EC Number 3.6.4.12 Acting on ATP; involved in cellular and subcellular movement
Subcellular Localization
  • Host nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
host cell nucleus A membrane-bounded organelle as it is found in the host cell in which chromosomes are housed and replicated. The host is defined as the larger of the organisms involved in a symbiotic interaction.

6 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
DNA helicase activity Unwinding of a DNA helix, driven by ATP hydrolysis.
endonuclease activity Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks.
metal ion binding Binding to a metal ion.

2 GO annotations of biological process

Name Definition
DNA replication The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA.
viral DNA genome replication The replication of a viral DNA genome.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNNGDSNRET DSTTRSDQSN LRESPTRSPS SEQCSMVATT SRKREWAYGG RGTMASLAKE
70 80 90 100 110 120
SQENFQYMAE ELEKMGNQFF GYVTGQSVKP SSAYISDVII LRDIQLRDQC LDVLREYGRS
130 140 150 160 170 180
RRNGLFGFSE EGDHIHVIHD CSYTNRSCRD IWLGQVKPFG TVQKTGKPVK YIWEFKRTDW
190 200 210 220 230 240
YDVFIYFFIR KRGERAIYIR GESGKIPSND ECVRWAREFK EREMVSSSDC TDYYECEQQE
250 260 270 280 290 300
HKISRRSDAG STNGRLYEKK TYSAGKFAYI RQKTKALLRK YYVSPISAIC DVPEFRDDDL
310 320 330 340 350 360
LCDPKNRDYI QAACEDFGKD LNAMSLREIY NLLTEDYNFT DDKELNPYAQ FISSMKYDNL
370 380 390 400 410 420
EGSLNIVNEL LKYQCNDDED LIVEFLTNLV NVLDRRIPKL NAFLIISPPS GGKNFFFDMI
430 440 450 460 470 480
FGLLLSYGQL GQANRHNLFA FQEAPNKRVL LWNEPNYESS LTDTIKMMFG GDPYTVRVKN
490 500 510 520 530 540
RMDAHVKRTP VIILTNNTVP FMYELAFSDR IIQYKWNAAP FLKDYELKPH PMTFFLLLSK
YNITF